Patents by Inventor Ulf Nehrbass

Ulf Nehrbass has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Single cell based reporter assay to monitor gene expression patterns with high spatio-temporal resolution
    Patent number: 9663833
    Abstract: The invention relates to a double-stranded polynucleotide comprising on its positive strand considered from its 5? end to its 3? end, (i) a promoter of a gene of interest or several promoters of various genes of interest selected among genes which are endogenous to a determined cell, and, (ii) one or several barcode(s) wherein each barcode contains at least one barcode unit formed of at least one, especially of multiple, recognition binding sites each binding site being composed of a nucleotide sequence, and wherein each of said barcode(s) is under the control of at least one of said promoter(s) for transcription. It further concerns use of said polynucleotide to monitor gene expression patterns in living cells, especially in single cells, with a rapid and high spatio-temporal resolution.
    Type: Grant
    Filed: September 12, 2008
    Date of Patent: May 30, 2017
    Assignee: INSTITUT PASTEUR
    Inventors: Musa Mhlanga, Jost Enninga, Philippe Sansonetti, Ulf Nehrbass
  • Genome Wide Visual Identification of Human Co-Factors of HIV-1 Infection
    Publication number: 20110183313
    Abstract: The present invention relates to the identification of human host factors involved in the early stage of HIV infection. Furthermore, it relates to the use of the identified genes for the elucidation of the mechanism of HIV-infection, as drug targets, and for identifying a compound useful in the treatment of HIV.
    Type: Application
    Filed: June 25, 2009
    Publication date: July 28, 2011
    Inventors: Neil Emans, Auguste Genovesio, Marc P. Windisch, Yong Jun Kwon, Sungyong Jung, Hi Chul Kim, Nam Youl Kim, Seo Yeon Choi, Ulf Nehrbass
  • SINGLE CELL BASED REPORTER ASSAY TO MONITOR GENE EXPRESSION PATTERNS WITH HIGH SPATIO-TEMPORAL RESOLUTION
    Publication number: 20110021369
    Abstract: The invention relates to a double-stranded polynucleotide comprising on its positive strand considered from its 5? end to its 3? end, (i) a promoter of a gene of interest or several promoters of various genes of interest selected among genes which are endogenous to a determined cell, and, (ii) one or several barcode(s) wherein each barcode contains at least one barcode unit formed of at least one, especially of multiple, recognition binding sites each binding site being composed of a nucleotide sequence, and wherein each of said barcode(s) is under the control of at least one of said promoter(s) for transcription. It further concerns use of said polynucleotide to monitor gene expression patterns in living cells, especially in single cells, with a rapid and high spatio-temporal resolution.
    Type: Application
    Filed: September 12, 2008
    Publication date: January 27, 2011
    Applicant: INSTITUT PASTEUR
    Inventors: Musa Mhlanga, Jost Enninga, Philippe Sansonetti, Ulf Nehrbass
  • Method of Detecting and/or Quantifying Expression of a Target Protein Candidate in a Cell, and a Method of Identifying a Target Protein of a Small Molecule Modulator
    Publication number: 20090275042
    Abstract: The present invention relates to a method of detecting and/or quantifying expression of a target protein candidate in a cell, and to a method of identifying a target protein of a small molecule modulator.
    Type: Application
    Filed: September 20, 2007
    Publication date: November 5, 2009
    Inventors: Neil Emans, Ulf Nehrbass