Abstract: The present invention relates to a cable comprising at least one layer comprising a polypropylene composition comprising (A) from 80.0 to 99.0 wt.-%, preferably from 82.5 to 97.2 wt. %, most preferably from 85.0 to 95.0 wt.-% of a copolymer of propylene and comonomer units selected from ethylene and alpha-olefins having from 4 to 12 carbon atoms having a total amount of comonomer units of from 10.0 to 16.0 wt %, preferably from 11.0 to 15.0 wt %, most preferably from 12.0 to 14.0 wt %, based on the total amount of monomer units of the copolymer of propylene (A): a melt flow rate MFR2 of from 0.5 to 5.0 g/10 min. preferably from 0.8 to 4.5 g/10 min. still more preferably from 1.0 to 4.3 g/10 min and most preferably from 1.2 to 4.0 g/10 min; a xylene cold soluble (XCS) fraction in a total amount of from 25.0 to 50.0 wt %, preferably from 27.5 to 45.0 wt %, more preferably from 30.0 to 42.5 wt % and most preferably from 32.5 to 40.

Abstract: The present invention relates to a cable comprising a polypropylene composition comprising (A) from 80.0 to 99.0 wt.-%, preferably from 82.5 to 97.2 wt. %, most preferably from 85.0 to 95.0 wt.-% of a copolymer of propylene and comonomer units selected from ethylene and alpha-olefins having from 4 to 12 carbon atoms having a total amount of comonomer units of from 10.0 to 16.0 wt %, preferably from 11.0 to 15.0 wt %, most preferably from 12.0 to 14.0 wt %, based on the total amount of monomer units of the copolymer of propylene (A); a melt flow rate MFR2 of from 0.5 to 2.5 g/10 min, preferably from 0.8 to 2.3 g/10 min, still more preferably from 1.0 to 2.0 g/10 min and most preferably from 1.2 to 1.7 g/10 min; a xylene cold soluble (XCS) fraction in a total amount of from 25.0 to 50.0 wt %, preferably from 27.5 to 45.0 wt %, more preferably from 30.0 to 42.5 wt % and most preferably from 32.5 to 40.0 wt %, based on the total weight amount of the copolymer of propylene (A); and (B) from 1.0 to 20.0 wt.

Abstract: The present invention relates to a polypropylene composition comprising (A) from 80.0 to 99.0 wt.-% of a copolymer of propylene and comonomer units selected from ethylene and alpha-olefins having from 4 to 12 carbon atoms having a total amount of comonomer units of from 10.0 to 16.0 wt %, based on the total amount of monomer units of the copolymer of propylene (A); a melt flow rate MFR2 of from 0.5 to 2.5 g/10 min; a xylene cold soluble (XCS) fraction in a total amount of from 25.0 to 50.0 wt %, based on the total weight amount of the copolymer of propylene (A); and (B) from 1.0 to 20.0 wt.-% of an ethylene polymer having a density of from 915 to 960 kg/m3; and a melt flow rate MFR5 (190° C., 5 kg) of from 0.05 to 5.0 g/10 min, an article comprising said polypropylene composition, preferably a cable comprising an insulation layer comprising said polypropylene composition, and the use of said polypropylene composition as cable insulation for medium and high voltage cables.

Abstract: A compound of the general formula I or II. The compound of formula I or II is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Furthermore, a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.

Abstract: The present disclosure relates to a thermal management system for a vehicle including a refrigerant system, a coolant system and a control unit. The coolant system includes a first control loop thermally coupled to an energy storage system, a second control loop thermally coupled to a drive train system, a third control loop thermally coupled to a radiator system, a first multiple valve unit and a second multiple valve unit, and a first heat exchanger configured to transfer heat to the refrigerant system. The first control loop, the second control loop and the third control loop are configured to transfer heat to the first heat exchanger. The first heat exchanger is arranged between the first multiple valve unit and the second multiple valve unit.

Abstract: The present invention relates to a cable comprising at least one layer comprising a polypropylene composition comprising (A) from 80.0 to 99.0 wt.-%, preferably from 82.5 to 97.2 wt. %, most preferably from 85.0 to 95.0 wt.-% of a copolymer of propylene and comonomer units selected from ethylene and alpha-olefins having from 4 to 12 carbon atoms having a total amount of comonomer units of from 10.0 to 16.0 wt %, preferably from 11.0 to 15.0 wt %, most preferably from 12.0 to 14.0 wt %, based on the total amount of monomer units of the copolymer of propylene (A); a melt flow rate MFR2 of from 0.5 to 2.5 g/10 min, preferably from 0.8 to 2.3 g/10 min, still more preferably from 1.0 to 2.0 g/10 min and most preferably from 1.2 to 1.7 g/10 min; a xylene cold soluble (XCS) fraction in a total amount of from 25.0 to 50.0 wt %, preferably from 27.5 to 45.0 wt %, more preferably from 30.0 to 42.5 wt % and most preferably from 32.5 to 40.

Abstract: A submarine cable core comprising a conductor which is surrounded by at least an inner semiconductive layer, an insulation layer and an outer semiconductive layer in that order; wherein said insulation layer comprises: a low density polyethylene homopolymer or low density polyethylene copolymer with at least one polyunsaturated comonomer and optionally one or more further comonomers; and, a copolymer comprising at least one polar comonomer selected from the group consisting of an alkyl acrylate, an alkyl methacrylate or vinyl acetate, wherein the amount of polar monomer units in the insulation layer is from 1 to 150 micromol per gram based on the total amount of polymer components in the insulation layer.

Abstract: The present disclosure relates to a device for sonicating a biological sample. In one embodiment, a sample tube holder is pivotally suspended in a mount of a sonication device, thus allowing for a rotational degree of freedom and/or lateral movement that provides an optimized contact area between the sonotrode and the sample tube. Also disclosed is a method for sonicating a biological sample using the device described herein.

Abstract: A D-galactopyranose compound of formula (1) wherein the pyranose ring is beta-D-galactopyranose, and these compounds are high affinity galectin-3 inhibitors for use in treatment of disorders relating to the binding of a galectin-3 to a ligand in a mammal.

Abstract: The present invention relates to a polypropylene composition comprising (A) a copolymer of propylene and comonomer units selected from ethylene and alpha-olefins having from 4 to 12 carbon atoms with a total amount of comonomer units of from 10.0 to 16.0 wt %, based on the total amount of monomer units in the polypropylene composition, and (B) an alpha-nucleating agent; wherein the polypropylene composition has a xylene cold soluble (XCS) fraction in a total amount of from 25.0 to 50.0 wt %, based on the total weight amount of the polypropylene composition, with an amount of comonomer units of at least 23.0 wt %, based on the total amount of monomer units in the xylene cold soluble (XCS) fraction, a melt flow rate MFR2 of from 0.5 to 5.

Abstract: The present invention relates to a polypropylene composition comprising a copolymer of propylene and comonomer units selected from ethylene and alpha-olefins having from 4 to 12 carbon atoms with a total amount of comonomer units of from 10.0 to 16.0 wt %, based on the total amount of monomer units in the polypropylene composition, wherein the polypropylene composition has a xylene cold soluble (XCS) fraction in a total amount of from 25.0 to 50.0 wt %, based on the total weight amount of the polypropylene composition, with an amount of comonomer units of at least 22 wt %, based on the total amount of monomer units in the xylene cold soluble (XCS) fraction, a melt flow rate MFR2 of from 0.5 to 2.

Abstract: An embodiment of the present invention relates to a compound of the general formula. The compound of formula is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Furthermore an embodiment of the present invention concerns a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.

Abstract: A D-galactopyranose compound of formula (1) wherein the pyranose ring is beta-D-galactopyranose, and these compounds are high affinity galectin-1 and/or 3 inhibitors for use in treatment of inflammation; fibrosis; scarring; keloid formation; aberrant scar formation; surgical adhesions; scleroderma; systemic sclerosis; septic shock; cancer; metastasising cancers; autoimmune diseases; metabolic disorders; heart disease; heart failure; aortic stenosis; atherosclerosis; pathological angiogenesis; eye diseases; metabolic diseases; insulin resistance; obesity; Diastolic HF; asthma; otosclerosis; mesothelioma; liver disorders Liver cancer; cholangiocarcinoma; biliary tract cancer; and neurodegenerative disorders.

Abstract: The present invention relates to a semiconductive composition comprising (A) at least 52.0 wt %, preferably from 55.0 to 90.0 wt %, more preferably from 60.0 to 85.0 wt %, most preferably from 65.0 to 80.0 wt % of a heterophasic propylene copolymer having a matrix phase and an elastomeric phase dispersed in said matrix phase, based on the total weight amount of the semiconductive composition; and (B) from 5.0 to 40.0 wt %, preferably from 10.0 to 38.0 wt %, more preferably from 15.0 to 35.0 wt %, most preferably from 20.0 to 33.0 wt % of carbon black based on the total weight amount of the semiconductive composition, an article comprising said semiconductive composition, preferably a cable comprising an semiconductive layer comprising said semiconductive composition and the use of said semiconductive composition as inner and/or outer semiconductive layer for medium and high voltage cables.

Abstract: Use of a cable, e.g. to carry power, in a salt water environment, e.g. in the sea or under the sea; said cable comprising a conductor which is surrounded by at least an inner semiconductive layer, an insulation layer and an outer semi conductive layer in that order; wherein said insulation layer comprises (i) at least 60 wt % of a low density polyethylene homo or low density polyethylene copolymer with at least one polyunsaturated comonomer and optionally one or more further comonomers; and, (ii) 10 to 35 wt % of a low density polyethylene copolymer of ethylene and at least one polar comonomer selected from the group consisting of an alkyl acrylate, an alkyl methacrylate or vinyl acetate.

Abstract: A crosslinkable and crosslinked polymer composition containing a low density polyethylene (LDPE) homopolymer or low density polyethylene (LDPE) copolymer has excellent direct current (DC) electrical properties. The crosslinked polymer composition has an electrical conductivity of 150 fS/m or less, when measured at 70° C. and a 30 kV/mm mean electric field from a non-degassed, 1 mm thick plaque sample of the crosslinked polymer composition when measured according to a direct current (DC) conductivity method. A cable can be surrounded by at least one layer of the polymer composition.

Abstract: The present disclosure relates to a device for sonicating a biological sample. In one embodiment, a sample tube holder is pivotally suspended in a mount of a sonication device, thus allowing for a rotational degree of freedom and/or lateral movement that provides an optimized contact area between the sonotrode and the sample tube. Also disclosed is a method for sonicating a biological sample using the device described herein.

Abstract: The present disclosure relates to a device for sonicating a biological sample. In one embodiment, a sample tube holder is pivotally suspended in a mount of a sonication device, thus allowing for a rotational degree of freedom and/or lateral movement that provides an optimized contact area between the sonotrode and the sample tube. Also disclosed is a method for sonicating a biological sample using the device described herein.

Abstract: A process for preparing a compound of formula (X) The process includes reacting a compound of formula (IX) with an acetylating agent in the presence of a base in a suitable solvent and at a suitable temperature for a sufficient reaction time for preparing the compound of formula X. The process is suitable for large scale synthesis.

Abstract: The present disclosure relates to a thermal management system for a vehicle including a refrigerant system, a coolant system and a control unit. The coolant system includes a first control loop thermally coupled to an energy storage system, a second control loop thermally coupled to a drive train system, a third control loop thermally coupled to a radiator system, a first multiple valve unit and a second multiple valve unit, and a first heat exchanger configured to transfer heat to the refrigerant system. The first control loop, the second control loop and the third control loop are configured to transfer heat to the first heat exchanger. The first heat exchanger is arranged between the first multiple valve unit and the second multiple valve unit.