Patents by Inventor Ulf Norinder

Ulf Norinder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3,5,3'-triiodothyronine receptor ligands
    Patent number: 5585404
    Abstract: Use of a compound selected from the group consisting of 3,5-diiodo-4-(2-N,N-diethylaminoethoxy)phenyl-(2-butylbenzofur-3-yl)methan ol hydrochloride (001), 2-methyl-3-(3,5-diiodo-4-(2-N,N-diethylaminoethoxy)-benzoyl)benzofuran hydrochloride (003), 2-n-butyl-3-(3,5-diiodo-4-carboxymethoxybenzoyl)benzofuran (005), 2-methyl-3-(3,5-diiodo-4-hydroxy-benzoyl)benzofuran (011), 2-methyl-3-(3,5-diiodo-4-carboxymethoxybenzyl)benzofuran (015), 4'-hydroxy-3'-iodo-3,5-diiodo-4-(2-N,N-diethylaminoethoxy)benzophenon hydrochloride (024), 2-butyl-3-(3-iodo-4-hydroxybenzoyl)benzofuran (029), 4'4'-dihydroxy-3'3,5-triiododiphenylmethan (032), which compound is a 3,5,3'-triiodothyronine (T-3) receptor ligand, for the preparation of a medicament for the therapeutic or prophylactic treatment of a disorder which depends on the expression of T-3 regulated genes, and pharmaceutical preparations comprising said compounds, are disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 17, 1996
    Inventors: Ulf Norinder, Jurgen Bajorath, Jay F. Stearns
  • Receptor ligands
    Patent number: 5567728
    Abstract: Use of a compound selected from the group consisting of 3,5-diiodo-4-(2-N, N-diethylaminoethoxy)phenyl-(2-butylbenzofur-3-yl)methanol hydrochloride (001), 2-methyl-3-(3,5-diiodo-4-(2-N,N-diethylaminoethoxy)-benzoyl)benzofuran hydrochloride (003), 2-n-butyl-3-(3,5-diiodo-4-carboxymethoxybenzoyl)benzofuran (005), 2-methyl-3-(3,5-diiodo-4-hydroxy-benzoyl)benzofuran (011), 2-methyl-3-(3,5-diiodo-4-carboxymethoxybenzyl)benzofuran (015), 4'-hydroxy-3'-iodo-3,5-diiodo-4-(2-N,N-diethylaminoethoxy)benzophenon hydrochloride (024), 2-butyl-3-(3-iodo-4-hydroxy-benzoyl)benzofuran (029), 4'4'-dihydroxy-3'3,5-triiododiphenylmethan (032), which compound is a 3,5,3'-triiodothyronine (T-3) receptor ligand, for the preparation of a medicament for the therapeutic or prophylactic treatment of a disorder which depends on the expression of T-3 regulated genes, and pharmaceutical preparations comprising said compounds, are disclosed.
    Type: Grant
    Filed: February 25, 1994
    Date of Patent: October 22, 1996
    Assignee: Karobio Aktiebolag
    Inventors: Ulf Norinder, Jurgen Bajorath, Jay F. Stearns
  • 1-(3'-fluoro-2',3'-dideoxy-.beta.-D-ribofuranosyl)-5-substituted pyrimidine nucleosides
    Patent number: 5506215
    Abstract: A 2',3'-deoxy-3'-fluoro-pyrimidine nucleoside having the formula: ##STR1## wherein R.sup.1 is OH or NH.sub.2 ;R.sup.2 is CF.sub.3, CH.sub.2 CH.sub.2 CH.sub.3, ##STR2## CH.sub.2 OCH.sub.3, CH.sub.2 SCH.sub.3, CH.dbd.CH.sub.2 CH.dbd.CH--CH.sub.3, C.tbd.CH, C.tbd.C--CH.sub.3 or CH.sub.2 --C.tbd.CH;or a pharmaceutically acceptable salt thereof.These nucleoside analogs exhibit antiviral activity against HIV.
    Type: Grant
    Filed: December 12, 1994
    Date of Patent: April 9, 1996
    Assignee: Medivir AB
    Inventors: Karl N. G. Johansson, BjoG. Lindborg, Ulf Norinder, Goran B. Stening