Abstract: K-Ras is the most frequently mutated oncogene in human cancer. Disclosed herein are compositions and methods for modulating K-Ras and treating cancer.

Abstract: The present invention relates to the use of a composition of formula (I): Fe9-a-b-cNiaCobMcS8-dSed, wherein M stands for one or more elements having in the ionic state an effective ionic radius in the range of 70-92 pm, a is a number within the range of 2.5?a?3.5, more preferably 2.7?a?3.3, b is a number within the range of 1.5?b?5.0, more preferably 1.5?b?4.0, most preferably 2.5?b?3.5, c is a number within the range of 0.0?c?2.0, more preferably 0.0?c?1.0, d is a number within the range of 0.0?d?4.0, more preferably 0.0?d?1.0, wherein the sum of a, b and c is in the range of 5?a+b+c?8 and wherein ?90 wt. % of the composition is in the pentlandite phase for electrocatalytic splitting of water, preferably for hydrogen evolution reaction.

Abstract: K-Ras is the most frequently mutated oncogene in human cancer. Disclosed herein are compositions and methods for modulating K-Ras and treating cancer.

Abstract: K-Ras is the most frequently mutated oncogene in human cancer. Disclosed herein are compositions and methods for modulating K-Ras and treating cancer.

Abstract: K-Ras is the most frequently mutated oncogene in human cancer. Disclosed herein are compositions and methods for modulating K-Ras and treating cancer.

Abstract: K-Ras is the most frequently mutated oncogene in human cancer. Disclosed herein are compositions and methods for modulating K-Ras and treating cancer.

Abstract: K-Ras is the most frequently mutated oncogene in human cancer. Disclosed herein are compositions and methods for modulating K-Ras and treating cancer.

Abstract: K-Ras is the most frequently mutated oncogene in human cancer. Disclosed herein are compositions and methods for modulating K-Ras and treating cancer.

Abstract: The present invention relates to the use of a composition of formula (I): Fe9-a-b-cNiaCobMcS8-dSed, wherein M stands for one or more elements having in the ionic state an effective ionic radius in the range of 70-92 pm, a is a number within the range of 2.5?a?3.5, more preferably 2.7?a?3.3, b is a number within the range of 1.5?b?5.0, more preferably 1.5?b?4.0, most preferably 2.5?b?3.5, c is a number within the range of 0.0?c?2.0, more preferably 0.0?c?1.0, d is a number within the range of 0.0?d?4.0, more preferably 0.0?d?1.0, wherein the sum of a, b and c is in the range of 5?a+b+c?8 and wherein ?90 wt. % of the composition is in the pentlandite phase for electrocatalytic splitting of water, preferably for hydrogen evolution reaction.

Abstract: K-Ras is the most frequently mutated oncogene in human cancer. Disclosed herein are compositions and methods for modulating K-Ras and treating cancer.

Abstract: K-Ras is the most frequently mutated oncogene in human cancer. Disclosed herein are compositions and methods for modulating K-Ras and treating cancer.

Abstract: Measured marine survey data can be processed analogously to modeled marine survey data analogously and a misfit can be calculated between the processed measured marine survey data and the processed modeled marine survey data. A model parameter in the modeled marine survey data can be updated based on the misfit. The model parameter can be a parameter of a subsurface location.

Abstract: K-Ras is the most frequently mutated oncogene in human cancer. Disclosed herein are compositions and methods for modulating K-Ras and treating cancer.

Abstract: In some embodiments, a motion detection and correction system and/or device for tracking and compensating for patient motion during a medical imaging scan can be adapted to be integrated into a medical imaging scanner, such as an MRI scanner, or be adapted to retrofit a pre-existing medical imaging scanner. In certain embodiments, the motion detection system and/or device can comprise one or more mounting brackets and a motion correction device housing, which can further comprise one or more detector modules and a power unit. In further embodiments, the collected motion data can be further analyzed by an image processing unit of the motion tracking and/or correction system.

Abstract: K-Ras is the most frequently mutated oncogene in human cancer. Disclosed herein are compositions and methods for modulating K-Ras and treating cancer.

Abstract: A system and method is provided for identifying degrading electrodes in a marine electromagnetic survey system. A system may comprise a sensor array operable for use in a marine electromagnetic survey system, wherein the sensor array comprises a plurality of electrodes. The system may comprise a shunt resistor connected to the electrodes and a processor operable to vary a resistance of the shunt resistor in the presence of a voltage across the electrodes. A method for identifying degrading electrodes may comprise measuring an electric field in a body of water with a pair of electrodes, wherein a shunt resistor is connected between the pair of electrodes. The method may comprise varying a resistance of the shunt resistor. The method may comprise measuring a voltage across the shunt resistor while varying the resistance of the shunt resistor to obtain measured voltages for different shunt resistor values.

Abstract: Provided herein are compositions, reactions mixtures, mutant Ras proteins, kits, substrates, and systems for selecting a Ras antagonist, as well as methods of using the same.

Abstract: Aspects described herein provide for a sensor assembly having an electrically isolated cable segment that may be used for geophysical prospecting. The sensor assembly generally includes a first cable segment comprising at least one electromagnetic (EM) sensor, and a second cable segment connected to the first cable segment and electrically isolated from the first cable segment. The second cable segment may be free of electrically conductive components. Alternatively, the second cable segment may have electrically conductive components that are not electrically connected to the first cable segment. The electrically isolated cable segment may reduce or eliminate undesired signal cross-feed from the EM source to the first cable segment, which may aid in maintaining data quality.

Abstract: K-Ras is the most frequently mutated oncogene in human cancer. Disclosed herein are compositions and methods for modulating K-Ras and treating cancer.

Abstract: The present invention provides a system and method for producing superconducting joints between superconductive segments of a Bi-2212 high-temperature superconducting (HTS) conductor, thereby eliminating the heat generating resistive joints that are commonly known in the art for connecting two or more smaller Bi-2212 conductive segments to create an Bi-2212 conductor of adequate length.