Patents by Inventor Ulf R. Knothe

Ulf R. Knothe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7879107
    Abstract: A composition and method for inducing bone growth and healing is provided. The composition is useful for promoting new bone synthesis, and to enhance the mechanical stability and longevity of orthopaedic implants. The composition includes a bone endogenous material which is used as raw material for the body's natural osteogenic mechanism to synthesize new bone. The composition is applied in a flow phase and then undergoes a phase change to a congealed phase. The resulting material has a dual mode porosity system, having a first order porosity to accommodate and promote convective diffusion of nutrient species into and through the material, and a second order porosity to accommodate osteoblastic migration therein without the need for osteoclastic resorption.
    Type: Grant
    Filed: February 20, 2003
    Date of Patent: February 1, 2011
    Assignee: The Cleveland Clinic Foundation
    Inventors: Melissa L. Knothe Tate, Ulf R. Knothe