Patents by Inventor Ulf Reimer

Ulf Reimer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TFPI inhibitors and methods of use
    Patent number: 8466108
    Abstract: The invention provides peptides that bind Tissue Factor Pathway Inhibitor (TFPI), including TFPI-inhibitory peptides, and compositions thereof. The peptides may be used to inhibit a TFPI, enhance thrombin formation in a clotting factor-deficient subject, increase blood clot formation in a subject, and/or treat a blood coagulation disorder in a subject.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: June 18, 2013
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Michael Dockal, Hartmut Ehrlich, Friedrich Scheiflinger, Ulf Reimer, Ulrich Reineke, Thomas Polakowski, Eberhard Schneider
  • 8-oxy-quinoline derivatives as bradykinin B2 receptor modulators
    Patent number: 8410134
    Abstract: The present invention is related to compound of the formula (I): or a pharmacologically acceptable salt, solvate, or hydrate thereof, wherein A is a 6-membered heteroaryl having from 1 to 3 heteroatoms, each independently selected from N or O and the other substituents are defined as in the claims.
    Type: Grant
    Filed: March 22, 2008
    Date of Patent: April 2, 2013
    Assignee: Shire Orphan Therapies GmbH
    Inventors: Christoph Gibson, Thomas Tradler, Karsten Schnatbaum, Jochen Pfeifer, Elsa Locardi, Dirk Scharn, Matthias Paschke, Ulf Reimer, Uwe Richter, Gerd Hummel, Ulrich Reineke
  • Method for determining the substrate specificity of an enzyme
    Patent number: 8029979
    Abstract: The invention relates to a method for determining the substrate specificity of an enzymatic activity comprising the following steps: providing an assembly comprising a plurality of amino acid sequences on a planar surface of a support material, whereby the amino acids are directionally immobilized; contacting and/or incubating of an enzymatic activity with the assembly; and detection of a reaction between one of the amino acid sequences that are immobilized on the assembly and the enzymatic activity. According to the invention, during the reaction of the enzymatic activity with the assembly, a change in the molecular weight of at least one of the amino acid sequences takes place.
    Type: Grant
    Filed: June 26, 2006
    Date of Patent: October 4, 2011
    Assignee: JPT Peptide Technologies GmbH
    Inventors: Jens Schneider-Mergener, Mike Schutkowski, Ulf Reimer, Liying Dong, Soren Panse, Dirk Scharn, Frank Osterkamp, Gerd Hummel, Laurence Jobron
  • NOVEL NPR-B AGONISTS
    Publication number: 20110077381
    Abstract: Disclosed are novel compounds having NPR-B agonistic activity. Preferred compounds are linear peptides containing 8-13 conventional or non-conventional L- or D-amino acid residues connected to one another via peptide bonds.
    Type: Application
    Filed: September 23, 2010
    Publication date: March 31, 2011
    Applicant: ALCON RESEARCH, LTD.
    Inventors: Frank Osterkamp, Heiko Hawlisch, Gerd Hummel, Tobias Knaute, Ulf Reimer, Ulrich Reineke, Uwe Richter, Bernadett Simon, Edgar Specker, Markus Woischnik, Mark R. Hellberg
  • 8-OXY-QUINOLINE DERIVATIVES AS BRADYKININ B2 RECEPTOR MODULATORS
    Publication number: 20100234344
    Abstract: The present invention is related to compound of the formula (I): or a pharmacologically acceptable salt, solvate, or hydrate thereof, wherein A is a 6-membered heteroaryl having from 1 to 3 heteroatoms, each independently selected from N or O and the other substituents are defined as in the claims.
    Type: Application
    Filed: March 22, 2008
    Publication date: September 16, 2010
    Applicant: JERINI AG
    Inventors: Christoph Gibson, Thomas Tradler, Karsten Schinatbaum, Jochen Pfeifer, Elsa Locardi, Dirk Scharn, Mathias Paschke, Ulf Reimer, Uwe Richter, Gerd Hummel, Ulrich Reineke
  • TFPI INHIBITORS AND METHODS OF USE
    Publication number: 20100173847
    Abstract: The invention provides peptides that bind Tissue Factor Pathway Inhibitor (TFPI), including TFPI-inhibitory peptides, and compositions thereof. The peptides may be used to inhibit a TFPI, enhance thrombin formation in a clotting factor-deficient subject, increase blood clot formation in a subject, and/or treat a blood coagulation disorder in a subject.
    Type: Application
    Filed: December 21, 2009
    Publication date: July 8, 2010
    Applicants: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE S.A., 3B Pharmaceuticals GmbH, Cosmix Molecular Biologicals GmbH
    Inventors: Michael Dockal, Hartmut Ehrlich, Friedrich Scheiflinger, Ulf Reimer, Ulrich Reineke, Thomas Polakowski, Eberhard Schneider
  • Method for determining the substrate specificity of an enzymatic activity and a device therefor
    Publication number: 20060234308
    Abstract: The invention relates to a method for determining the substrate specificity of an enzymatic activity comprising the following steps: providing an assembly comprising a plurality of amino acid sequences on a planar surface of a support material, whereby the amino acids are directionally immobilised; contacting and/or incubating of an enzymatic activity with the assembly; and detection of a reaction between one of the amino acid sequences that are immobilised on the assembly and the enzymatic activity. According to the invention, during the reaction of the enzymatic activity with the assembly, a change in the molecular weight of at least one of the amino acid sequences takes place.
    Type: Application
    Filed: June 26, 2006
    Publication date: October 19, 2006
    Applicant: JERINI AG
    Inventors: Jens Schneider-Mergener, Mike Schutkowski, Ulf Reimer, Liying Dong, Soren Panse, Dirk Scharn, Frank Osterkamp, Gerd Hummel, Laurence Jobron
  • Method for determining the substrate specificity of an enzymatic activity and a device therefor
    Publication number: 20040171097
    Abstract: The invention relates to a method for determining the substrate specificity of an enzymatic activity comprising the following steps: providing an assembly comprising a plurality of amino acid sequences on a planar surface of a support material, whereby the amino acids are directionally immobilised; contacting and/or incubating of an enzymatic activity with the assembly; and detection of a reaction between one of the amino acid sequences that are immobilised on the assembly and the enzymatic activity. According to the invention, during the reaction of the enzymatic activity with the assembly, a change in the molecular weight of at least one of the amino acid sequences takes place.
    Type: Application
    Filed: February 10, 2004
    Publication date: September 2, 2004
    Inventors: Jens Schneider-Mergener, Mike Schutkowski, Ulf Reimer, Liying Dong, Soren Panse, Dirk Scharn, Frank Osterkamp, Gerd Hummel, Laurence Jobron