Patents by Inventor Ulises D. ORLANDO

Ulises D. ORLANDO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ACYL-COA SYNTHETASE 4 (ACSL4) INHIBITORY COMPOUND
    Publication number: 20220133731
    Abstract: A new compound of formula A for the treatment of aggressive and/or resistant tumors expressing acyl-CoA synthetase 4 (ACSL4) and/or depending on steroids action. More particularly, the compound of the present invention inhibits tumor growth in ACSL4-expressing breast and prostate cancers, inhibits steroid synthesis and sensitizes cells towards chemotherapeutic and hormone therapy agents. Pharmaceutical compositions comprising the ACSL4-inhibitory compound of the invention, pharmaceutical combinations thereof with other anticancer agents and use in therapy.
    Type: Application
    Filed: February 20, 2020
    Publication date: May 5, 2022
    Inventors: Ernesto J. PODESTÁ, Paula M. MALOBERTI, Ulises D. ORLANDO, Ana F. CASTILLO, Angela R. SOLANO, Pablo LORENZANO MENNA, Daniel E. GOMEZ, Sergio H. SZAJNMAN, Jessica G. PRADA, Juan B. RODRIGUEZ