Patents by Inventor Ulrich Groth

Ulrich Groth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptidic sulfonamides
    Patent number: 7759302
    Abstract: The invention relates to novel peptides which are biologically active as ligands of blood platelet integrin GPIIbIIIa and the ?v integrins, preferably the av?s and ?v?3 integrin, having the formula (I): R1-Arg-X-Asp-Leu-Asp-Ser-Leu-Arg-R2 (I), in which R1 denotes H, acetyl or acyl and R2 denotes -Oh, OR3NH2, NHR3, N(R3)2 R3 denotes atkyl, aralkyl, aryl, Het and X denotes an amino acid of the formula (II), in which A denotes (CH2)n R4 denotes H, alkyl, aralkyl or aryl, and n denotes 1, 2, 3, 4, 5 or 6, and the amino acid of the formula (II) is bonded to the adjacent Arg via a peptide bond of the ?-amino group and to the ?-amino group of the adjacent Asp via a peptide bond of the ?-carboxyl group.
    Type: Grant
    Filed: January 14, 2004
    Date of Patent: July 20, 2010
    Assignee: Merck Patent GmbH
    Inventors: Alfred Jonczyk, Ulrich Groth, Gunther Zischinsky
  • Peptidic sulfonamides
    Publication number: 20060148716
    Abstract: The invention relates to novel peptides which are biologically active as ligands of blood platelet integrin GPIIbIIIa and the ?v integrins, preferably the ?v?s and ?v?3 integrin, having the formula (I): R1-Arg-X-Asp-Leu-Asp-Ser-Leu-Arg-R2 (I), in which R1 denotes H, acetyl or acyl and R2 denotes -Oh, OR3 NH2,NHR3, N(R3)2 R3 denotes atkyl, aralkyl, aryl, Het and X denotes an amino acid of the formula (II), in which A denotes (CH2)n R4 denotes H, alkyl, aralkyl or aryl, and n denotes 1, 2, 3, 4, 5 or 6, and the amino acid of the formula (II) is bonded to the adjacent Arg via a peptide bond of the ?-amino group and to the ?-amino group of the adjacent Asp via a peptide bond of the ?-carboxyl group.
    Type: Application
    Filed: January 14, 2004
    Publication date: July 6, 2006
    Inventors: Alfred Jonczyk, Ulrich Groth, Gunther Zischinsky
  • Process for the preparation of dipeptides with C-terminal non-proteinogenous amino acids
    Patent number: 5157145
    Abstract: Process for producing dipeptides from non-proteinogenic amino acids with terminal carbon atoms.
    Type: Grant
    Filed: July 17, 1990
    Date of Patent: October 20, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Ulrich Schoellkopf, Ulrich Groth, Meinolf Lange
  • Process for preparing peptides with N-terminal non-proteinogenous amino acids
    Patent number: 5138071
    Abstract: A process for preparing dipeptides with N-terminal non-proteinogenous amino acids of the formula ##STR1## in which R.sup.1 to R.sup.6 have the meaning stated in the description, from compounds of the formula ##STR2## is described.
    Type: Grant
    Filed: March 18, 1991
    Date of Patent: August 11, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Ulrich Schoellkopf, Ulrich Groth, Meinolf Lange