Abstract: A microdialysis probe with a probe body, a probe needle for introduction into a tissue, an inlet line and an outlet line for a perfusion solution and a dialysis membrane, wherein at least one hollow channel forms the outlet line and extends at least partly spirally about the probe needle on an external surface of the probe needle. The inlet for the perfusion solution may also be in the form of spiral about the external surface of the probe needle.

Abstract: A device for facilitating the use or application of skin penetrators, the device including a puncturing part for piercing the skin, an indwelling part which can be introduced into the skin through an opening generated by the puncturing part and remains there, wherein the puncturing part and indwelling part are operably associated with the device, and a guide operably associated with the device, wherein, in use, the indwelling part is moved, via the guide, into a position of use after the puncturing part has pierced the skin. In some embodiments, the puncturing and indwelling parts are separate from each other prior to use. A method of using skin penetrators is encompassed and includes sequentially introducing the puncturing part and the indwelling part into the skin.

Abstract: An infusion system comprises an infusion unit for infusing fluid into a user's body and a remote control for wirelessly receiving or sending signals to the infusion unit. The infusion system is capable of operating in two separate modes, namely a remote control mode and a direct control mode. In the remote control mode, an infusion command is generated by an input devise of the remote control. The verification to a user that the command has been received, executed or transmitted is outputted by an output device in the remote controller. In the direct control mode the infusion command is generated by an input device of the infusion unit. The verification to a user that the command has been received, executed or transmitted is outputted by an output device in the infusion unit.

Abstract: An ambulatory medical device and a method of communication between medical devices are disclosed. In one embodiment, the medical device includes a module for communication with at least a second medical device wherein the module for communication is adapted to be activated by a value of a physiological parameter of an animal. In one embodiment, the method of the present invention involves a first medical device and at least a second medical device wherein the communication between said medical devices is activated by a value of a physiological parameter of an animal.

Abstract: A diabetes care system for detection of an analyte and method for selective data transmission are disclosed. The diabetes care system has a mobile component and a base station, wherein a data transmission occurring between the mobile component and the base station within a time interval in which a wireless communication link exists, wherein is selectively performed in such a manner that within the time interval, a first partial set of the data is transmitted from the mobile component to the base station. The first partial set is selected using a processor-controlled selection algorithm in such a manner that the data transmitted in the time interval is representative of the entirety of the data stored in the mobile component.

Abstract: A patient device including a case and a user interface for interaction between a patient and the patient device, wherein at least a part of the user interface is separable from the case and may be used or recognized by the patient.

Abstract: A method for adjusting a sensor, continuous sensor or automatic measuring system in an interstitium including the steps of adjusting the steepness of a measuring curve and a standard offset (standard axis intercept) prior to the use of the sensor, continuous sensor or measuring system, and adapting the offset by a point calibration by using a reference measure or value during the use. The present invention encompasses sensors, continuous sensors or automatic measuring systems calibrated or adjusted in accordance with the method, and in some embodiments, the offset adjusted prior to use is rectified according to the difference between a value determined by the sensor, continuous sensor or measuring system taking into account the standard steepness and the reference value.

Abstract: A micro perfusion device including a casing, a perfusate supply, an inner cannula forming an inner lumen between a front cannula opening which is distal when the device is subcutaneously positioned and a rear cannula opening, the inner lumen being connected or connectable to the perfusate supply via the rear cannula opening, a perfusion cannula projecting from a lower side of the casing and surrounding the inner cannula, an outer lumen between the inner cannula and the perfusion cannula, a collecting container for the perfusate, and a perfusate outlet connecting the outer lumen to the collecting container, wherein the collecting container has a variable volume and a partial vacuum with respect to a pressure prevailing in the perfusate supply may be generated in the collecting container.

Abstract: A micro perfusion device including a casing, a perfusate supply, an inner cannula forming an inner lumen between a front cannula opening which is distal when the device is subcutaneously positioned and a rear cannula opening, the inner lumen being connected or connectable to the perfusate supply via the rear cannula opening, a perfusion cannula projecting from a lower side of the casing and surrounding the inner cannula, an outer lumen between the inner cannula and the perfusion cannula, a collecting container for the perfusate, and a perfusate outlet connecting the outer lumen to the collecting container, wherein the collecting container has a variable volume and a partial vacuum with respect to a pressure prevailing in the perfusate supply may be generated in the collecting container.

Abstract: A device for administering a substance including a measuring mechanism for measuring, without contact, a position, the measuring involving at least two elements of the device, at least one of the elements moveable with respect to the other, the measuring mechanism including at least two optical sensors for sensing a relative movement between the elements, the relative movement providing a profile trajectory. The present invention encompasses a method for measuring, without contact, a relative position between elements or structures which can be moved relative to each other, wherein sensors sense and/or record a profile trajectory associated with the elements or structures when one element is moved relative to another element, the trajectory processed to determine the position.

Abstract: A device for the in-vivo measuring of a constituent of a body fluid, the device including a light emitter which emits light in a wavelength range to which the constituent is sensitive and which is implantable in living tissue, and a light detector which, when the device is in a measuring position, receives the light emitted by the emitter and outputs a signal depending on the amount of light received, from which signal the constituent may be measured, wherein the light detector is situated outside the tissue when the device is in the measuring position.

Abstract: The invention provides a device and methods for analysing body fluids wherein the device is implanted in the body and provides for both the delivery of substances into the body and for the testing of body fluids.

Abstract: The invention provides a device and methods for analysing body fluids wherein the device is implanted in the body and provides for both the delivery of substances into the body and for the testing of body fluids.

Abstract: A microdialysis probe with a probe body, a probe needle for introduction into a tissue, an inlet line and an outlet line for a perfusion solution and a dialyis membrane, wherein at least one hollow channel forms the outlet line and extends at least partly spirally about the probe needle on an external surface of the probe needle. The inlet for the perfusion solution may also be in the form of spiral about the external surface of the probe needle.

Abstract: The invention provides a device and methods for analysing body fluids wherein the device is implanted in the body and provides for both the delivery of substances into the body and for the testing of body fluids.

Abstract: A device for delivering a liquid agent in doses, the device including a receptacle for storing the liquid agent and a propulsion mechanism for advancing a piston toward an outlet of the receptacle in order to expel a dose of the agent, wherein the propulsion mechanism permanently acts on the piston with a propulsive force, and wherein the device further includes a mechanism for releasably blocking a piston advance. The invention encompasses embodiments in the form of an infusion pump adapted to include the device for delivering and a controller for controlling at least the mechanism for releasably blocking.

Abstract: A method and apparatus for determining solute levels by affinity viscosimetry involving a sensitive fluid, in which the sensitive fluid flows continuously through a first hydraulic resistor in the flow direction of the dialysis chamber, and the sensitive fluid modified by dialysis simultaneously flows through another resistor, wherein the pressure differences between the resistors is determined on-line with the aid of pressure sensors and converted into a relative value which is approximately proportional to the concentration of solute.

Abstract: A micro perfusion device and method for obtaining at least one constituent of a body fluid. The at least one constituent is obtained using a subcutaneously-positioned perfusion catheter into which perfusate is introduced by a supply channel and an injection needle. The perfusate absorbs the at least one constituent as it flows out of the perfusion catheter and through a discharge channel.

Abstract: The present invention provides a module for a computer interface including a transducer wherein the transducer receives a measurement value and makes this measurement value available for monitoring an individual's health by means of the computer interface, for example, for monitoring an individual's blood glucose level, wherein the measurement value is obtained by means of a sensor.

Abstract: A method and apparatus for determining solute levels by affinity viscosimetry involving a sensitive fluid, in which the sensitive fluid flows continuously through a first hydraulic resistor in the flow direction of the dialysis chamber, and the sensitive fluid modified by dialysis simultaneously flows through another resistor, wherein the pressure differences between the resistors is determined on-line with the aid of pressure sensors and converted into a relative value which is approximately proportional to the concentration of solute.