Patents by Inventor Ulrich Kohnert

Ulrich Kohnert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilized compositions having human tissue type plasminogen activator enzymatic activity
    Patent number: 5366730
    Abstract: Pharmaceutical preparation of a protein with t-PA activity with an enzymatic activity of at least 0.25 MU/ml. and a pH value of 4.5 to 9 which contains a substance of the group citric acid, ascorbic acid, 2-oxoglutaric acid, fumaric acid, Tris and EDTA in a concentration of at least 0.2 mole/l., as well as a medicament based on a protein with t-PA activity and processes for its preparation.
    Type: Grant
    Filed: April 6, 1993
    Date of Patent: November 22, 1994
    Assignee: Boehringer Mannheim GmbH
    Inventors: Ulrich Kohnert, Rainer Rudolph
  • Stabilized compositions containing non-glysylated human tissue type plasminogen activator derivative K2P pro
    Patent number: 5352452
    Abstract: Stabilized compositions containing a non-glycosylated human tissue type plasminogen activator derivative are disclosed. The derivative is referred to as K2P pro. The composition has enzymatic activity of at least 1.1 mU/ml, a pH of from 4.5 to 6.5, and contains citrate as well as at least one of a variety of different compounds.
    Type: Grant
    Filed: August 2, 1991
    Date of Patent: October 4, 1994
    Assignee: Boehringer Mannheim GmbH
    Inventors: Ulrich Kohnert, Rainer Rudolph
  • Compositions containing non-glycosylated human tissue type plasminogen activator
    Patent number: 5352453
    Abstract: Pharmaceutical compositions containing non-glycosylated human tissue type plasminogen activator (t-PA) having enzymatic activity of at least 0.1 MU/ml are disclosed. The compositions have a pH of from 4.5 to 6, contain citrate, and at least one other compound.
    Type: Grant
    Filed: August 6, 1991
    Date of Patent: October 4, 1994
    Assignee: Boehringer Mannheim GmbH
    Inventors: Ulrich Kohnert, Rainer Rudolph
  • Thrombolytically active non-glycosylated protein
    Patent number: 5223256
    Abstract: A new thrombolytically active protein is not glycosylated and consists of the following amino acid sequence: ##STR1## or said amino acid sequence with an additional N-terminal methionine. DNA sequences encoding the thrombolytically active, non-glycosylated protein and pharmaceutical compositions containing said protein are also disclosed. The protein possesses particularly favorable properties when used to dissolve blood clots.
    Type: Grant
    Filed: September 28, 1990
    Date of Patent: June 29, 1993
    Assignee: Boehringer Mannheim GmbH
    Inventors: Anne Stern, Ulrich Kohnert, Rainer Rudolph, Stephan Fischer, Ulrich Martin