Patents by Inventor Ulrich Luecking

Ulrich Luecking has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carbamoylsulphoximides as protein kinase inhibitors
    Publication number: 20080167330
    Abstract: The invention relates to carbamoylsulphoximides as protein kinase inhibitors of the general formula 1.
    Type: Application
    Filed: August 28, 2007
    Publication date: July 10, 2008
    Inventors: Ulrich Luecking, Gerhard Siemeister, Rolf Jautelat
  • SUBSTITUTED SULPHOXIMINES AS TIE2 INHIBITORS AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME
    Publication number: 20080064696
    Abstract: The invention relates to substituted sulphoximines according to the general formula (I): in which A, E, G, X, R1, R2, R3, R4, R5, R6, R7, R8, m, p, q, are given in the claims, and salts thereof, to pharmaceutical compositions comprising said substituted sulphoximines, to methods of preparing said substituted sulphoximines as well as the use thereof for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with Tie2 signalling.
    Type: Application
    Filed: July 11, 2007
    Publication date: March 13, 2008
    Inventors: Ingo Hartung, Georg Kettschau, Hans Briem, Karl-Heinz Thierauch, Ulrich Luecking, Ulf Boemer, Martin Krueger
  • SULPHIMIDES AS PROTEIN KINASE INHIBITORS
    Publication number: 20080058358
    Abstract: The invention relates to sulphimides as protein kinase inhibitors of the general formula I
    Type: Application
    Filed: June 7, 2007
    Publication date: March 6, 2008
    Inventors: Ulrich Luecking, Duy Nguyen, Arne von Bonin, Oliver von Ahsen, Gerhard Siemeister, Rolf Jautelat, Wolf-Dietrich Doecke
  • Sulfoximine-substituted pyrimidines as CDK-and/or VEGF inhibitors, their production and use as pharmaceutical agents
    Patent number: 7338958
    Abstract: This invention relates to pyrimidine derivatives of general formula I in which Q, R1, R2, R3, R4, R5, X, and m have the meanings that are contained in the description, as inhibitors of cyclin-dependent kinases and VEGF-receptor tyrosine kinases, their production as well as their use as medications for treatment of various diseases.
    Type: Grant
    Filed: October 18, 2004
    Date of Patent: March 4, 2008
    Assignee: Schering AG
    Inventors: Ulrich Luecking, Gerhard Siemeister, Martin Krueger, Rolf Jautelat
  • SULFONAMIDO-MACROCYCLES AS TIE2 INHIBITORS AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME
    Publication number: 20080039482
    Abstract: The invention relates to sulfonamido-macrocycles according to the general formula (I): in which R1, R2, R4, R5, R6, A, B, C, L, X, Y, Z, n, and m are as defined in the claims, and salts, N-oxides, or solvates thereof, to pharmaceutical compositions comprising said sulfonamido-macrocycles, to methods of preparing said sulfonamido-macrocycles as well as the use thereof for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with Tie2 signalling.
    Type: Application
    Filed: June 20, 2007
    Publication date: February 14, 2008
    Inventors: Ingo Hartung, Hans Briem, Georg Kettschau, Karl-Heinz Thierauch, Ulrich Luecking, Ulf Boemer, Martina Schaefer, Philip Lienau
  • Macrocyclic pyrimidines, their production and use as pharmaceutical agents
    Patent number: 7312225
    Abstract: Macrocyclic pyrimidine derivatives of general formula I in which R1 to R5, X, Y, A, B, m and n have the meanings that are contained in the description, as inhibitors of the cyclin-dependent kinase, their processes for production as well as their use as medications for treating various diseases are described.
    Type: Grant
    Filed: August 20, 2003
    Date of Patent: December 25, 2007
    Assignee: Bayer Schering Pharma AG
    Inventors: Ulrich Luecking, Gerhard Siemeister, Martina Schaefer, Hans Briem
  • CDK-inhibitory pyrimidines, their production and use as pharmaceutical agents
    Patent number: 7291624
    Abstract: This invention relates to pyrimidine derivatives of general formula I in which R1, R2, X, A and B have the meanings that are contained in the description, as inhibitors of the cyclin-dependent kinases, their production as well as their use as medications for treating various diseases.
    Type: Grant
    Filed: May 11, 2004
    Date of Patent: November 6, 2007
    Assignee: Bayer Schering Pharma AG
    Inventors: Thomas Brumby, Rolf Jautelat, Olaf Prien, Martina Schäfer, Gerhard Siemeister, Ulrich Lücking, Christoph Huwe
  • CDK-inhibitory 2-heteroaryl-pyrimidines, their production and use as pharmaceutical agents
    Patent number: 7288547
    Abstract: This invention relates to 2-heteroaryl-pyrimidine derivatives of general formula I or If as inhibitors of the cyclin-dependent kinases, their production as well as their use as medications for treating various diseases.
    Type: Grant
    Filed: October 27, 2003
    Date of Patent: October 30, 2007
    Assignee: Schering AG
    Inventors: Ulrich Lücking, Martin Kruger, Rolf Jautelat, Olaf Prien, Gerhard Siemeister, Alexander Ernst
  • Compound and a composition including such a compound
    Patent number: 7235561
    Abstract: This invention relates to pyrimidine derivatives of general formula I in which R1, R2, X, A and B have the meanings that are contained in the description, as inhibitors of the cyclin-dependent kinases, their production as well as their use as medications for treating various diseases.
    Type: Grant
    Filed: May 29, 2002
    Date of Patent: June 26, 2007
    Assignee: Schering AG
    Inventors: Thomas Brumby, Rolf Jautelat, Olaf Prien, Martina Schäfer, Gerhard Siemeister, Ulrich Lücking, Christoph Huwe
  • Sulfoximine-macrocycle compounds and salts thereof, pharmaceutical compositions comprising said compounds, methods of preparing same and uses of same
    Publication number: 20060252782
    Abstract: The invention relates to macrocyctic sulfoximines of the general Formula I: wherein A, X, Y, R1, R2 and R3 have the meaning as given in the specification and the claims, and to salts thereof; to pharmaceutical compositions comprising the macrocyclic sulfoximines, and to a method of preparing the macrocyclic sulfoximines, as well as the use thereof for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with angiopoietin and therefore influence Tie2 signalling.
    Type: Application
    Filed: April 7, 2006
    Publication date: November 9, 2006
    Inventors: Ulrich Luecking, Georg Kettschau, Hans Briem, Wolfgang Schwede, Martina Schaefer, Karl-Heinz Thierauch, Manfred Husemann
  • N-aryl-sulfoximine-substituted pyrimidines as CDK-and/or VEGF inhibitors, their production and use as pharmaceutical agents
    Publication number: 20060229325
    Abstract: This invention relates to pyrimidine derivatives of general formula (I) in which Q, R1, R2, R3, R4, R5, X, and m have the meanings that are contained in the description, as inhibitors of cyclin-dependent kinases and VEGF-receptor tyrosine kinases, their production as well as their use as medications for treatment of various diseases.
    Type: Application
    Filed: March 22, 2006
    Publication date: October 12, 2006
    Inventors: Ulrich Luecking, Gerhard Siemeister, Rolf Jautelat
  • Sulfonamido-macrocycles as Tie2 inhibitors and the salts thereof, a pharmaceutical composition comprising these compounds, the method of preparing and the use thereof
    Publication number: 20060194823
    Abstract: The invention relates to sulfonamido-macrocycles according to the general Formula I and the salts thereof, to pharmaceutical compositions comprising the sulfonamido-macrocycles and to a method of preparing the sulfonamido-macrocycles as well as the use thereof for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with angiopoietin and therefore influence Tie2 signalling. wherein R1, R2, R4, A, X, Y, Z and m have the meaning as given in the specification and the claims.
    Type: Application
    Filed: December 21, 2005
    Publication date: August 31, 2006
    Inventors: Georg Kettschau, Hans Briem, Ingo Hartung, Ulrich Luecking, Martina Schaefer, Karl-Heinz Thierauch, Wolfgang Schwede, Manfred Husemann
  • Sulfonamido-macrocycles and the salts thereof, a pharmaceutical composition comprising these compounds, the method of preparing and the use thereof
    Publication number: 20060167030
    Abstract: The invention relates to sulfonamido-macrocycles according to the general Formula I and the salts thereof, to pharmaceutical compositions comprising the sulfonamido-macrocycles and to a method of preparing the sulfonamido-macrocycles as well as the use thereof for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with angiopoietin and therefore influence Tie2 signalling. wherein R1, R2 and R3 have the meaning as given in the specification and the claims.
    Type: Application
    Filed: December 21, 2005
    Publication date: July 27, 2006
    Inventors: Georg Kettschau, Hans Briem, Andreas Huth, Ulrich Luecking, Martina Schaefer, Karl-Heinz Thierauch, Wolfgang Schwede, Manfred Husemann
  • Sulfoximine-substituted pyrimidines as CDK-and/or VEGF inhibitors, their production and use as pharmaceutical agents
    Publication number: 20050176743
    Abstract: This invention relates to pyrimidine derivatives of general formula I in which Q, R1, R2, R3, R4, R5, X, and m have the meanings that are contained in the description, as inhibitors of cyclin-dependent kinases and VEGF-receptor tyrosine kinases, their production as well as their use as medications for treatment of various diseases.
    Type: Application
    Filed: October 18, 2004
    Publication date: August 11, 2005
    Inventors: Ulrich Luecking, Gerhard Siemeister, Martin Krueger, Rolf Jautelat
  • Macrocyclic pyrimidines, their production and use as pharmaceutical agents
    Publication number: 20040209895
    Abstract: Macrocyclic pyrimidine derivatives of general formula I 1
    Type: Application
    Filed: August 20, 2003
    Publication date: October 21, 2004
    Applicant: Schering AG
    Inventors: Ulrich Luecking, Gerhard Siemeister, Martina Schaefer, Hans Briem