Abstract: The invention relates to lyso-phosphatidylcholine (LysoPC), or a suitable precursor or derivative thereof, or a composition containing LysoPC and/or one or more suitable precursors or derivatives thereof, for use in the treatment and aftercare of inflammatory diseases in humans that involve lowering of the LysoPC level, including the treatment, prevention or support of treatment and aftercare of viral and bacterial pneumonias and sepsis, including pneumonia and sepsis as a consequence of influenza, Covid-19, ARDS, cancer, for supporting immunotherapy in cancer in view of effectiveness and for reducing side-effects, such as pneumonitis, colitis or hepatitis, and for reducing undesirable vaccination responses. The invention further relates to alpha-glycerophosphocholine (alpha-GPC), or a variant thereof, or a composition containing alpha-GPC and/or one or more variants thereof, for use in the treatment and aftercare of cancers and tumor cachexia.

Abstract: The invention relates to a rotor (10) of a dual centrifuge wherein the rotor has a rotor head (12) and an additional rotational mechanism for at least one rotational unit (22) which is provided in the rotor head (12) and comprises a bearing unit (70) and a rotational head (24) that is connected to the bearing unit (70) which is rotatably mounted and can be driven relative to the rotor head (12) by an additional rotational mechanism, an opening (16) for the rotational unit (22) being provided in which the rotational unit is accommodated and by means of which the bearing (70) is arranged such that it is fixed relative to the rotor head (12).

Abstract: The invention relates to a rotational unit (10) for a rotor of a dual centrifuge, said rotational unit having a bearing (14) and a rotational head (24) which is connected to the bearing (14), is mounted therein such that it can rotate about an axis of rotation and can be driven relative to the rotor by an additional rotational mechanism of the centrifuge, the rotational head (24) being detachably connected to the receiving unit (40, 80) for conjoint rotation, which receiving unit comprises a sample container receptacle (60, 70, 100, 110) for at least one sample container.

Abstract: A dual centrifuge (10) embodies the following: a driveshaft (16), a rotor (20), which is mounted on the driveshaft (16) and which can be removed axially in a removal direction (E), for a dual centrifuge, having at least one rotational unit (30); an opening (18) in the rotor (20), wherein an end region (16a) of the driveshaft (16) at least engages into said opening; and an additional drive mechanism (32) for the rotational unit or the rotational units (30). The dual centrifuge additionally has a design for operating various additional types of rotors; however, only one rotor (20, 40, 50) can be arranged on the driveshaft (16) at all times. The various rotor types (40, 50) are also adapted to the additional drive mechanism (32) for the rotational units (30) such that the function is not adversely affected. A design for operating at least one angular head rotor (40) and a swing-out rotor (50). For this purpose, the driveshaft (16) and the various rotor types (40, 50) are adapted to each other.

Abstract: The invention relates to a method for producing lipid-based nanoparticles using a dual asymmetrical centrifuge, products produced by means of said method, kits for producing said nanoparticles using a dual asymmetrical centrifuge, and accessories for carrying out the inventive method.

Abstract: A rotor (10) of a dual centrifuge which can be rotated about a drive axis (A) in a centrifuge, which rotor comprises at least two rotary units (26) that are arranged symmetrically to one another and have a bearing (32) and a rotary head (30) which is connected to the bearing (32) and which is mounted in the bearing (32) so as to be rotatable about a rotational axis (R1, R2), which rotary head (30) can be driven about the rotational axis (R1, R2) relative to the rotor by another rotary mechanism (46) of the centrifuge and has a rotary head receiving unit (80) for at least one sample container or at least one sample container receptacle (100, 110), with the rotational axis (R1, R2) of the rotary head (30) being inclined relative to the drive axis (A) of the rotor, the rotary head receiving unit (80) being designed to receive an elongated sample container receptacle (100, 110) or an elongated sample container, and the longitudinal axis of the sample container receptacle (100, 110) introduced into the rotary head

Abstract: The invention relates to a rotor (10) of a dual centrifuge which can be rotated about a drive axis (A) in a centrifuge, which rotor comprises at least two rotary units (26) that are arranged symmetrically to one another and have a bearing (32) and a rotary head (30) which is connected to the bearing (32) and which is mounted in the bearing (32) so as to be rotatable about a rotational axis (R1, R2), which rotary head (30) can be driven about the rotational axis (R1, R2) relative to the rotor by another rotary mechanism (46) of the centrifuge and has a rotary head receiving unit (80) for at least one sample container or at least one sample container receptacle (100, 110), with the rotational axis (R1, R2) of the rotary head (30) being inclined relative to the drive axis (A) of the rotor, the rotary head receiving unit (80) being designed to receive an elongated sample container receptacle (100, 110) or an elongated sample container, and the longitudinal axis of the sample container receptacle (100, 110) introd

Abstract: The invention relates to a dual centrifuge (10) which has the following: a driveshaft (16), a rotor (20), which is mounted on the driveshaft (16) and which can be removed axially in a removal direction (E), for a dual centrifuge, having at least one rotational unit (30); an opening (18) in the rotor (20), wherein an end region (16a) of the driveshaft (16) at least engages into said opening; and an additional drive mechanism (32) for the rotational unit or the rotational units (30). The dual centrifuge additionally has a design for operating various additional types of rotors; however, only one rotor (20, 40, 50) can be arranged on the driveshaft (16) at all times. The various rotor types (40, 50) are also adapted to the additional drive mechanism (32) for the rotational units (30) such that the function is not adversely affected. The invention is characterized by a design for operating at least one angular head rotor (40) and a swing-out rotor (50).

Abstract: The invention relates to a rotor (10) of a dual centrifuge, said rotor having a rotor head (12) and an additional rotational mechanism for at least one rotational unit (22) which is provided in the rotor head (12) and comprises a bearing (70) and a rotational head (24) that is connected to the bearing (70), is rotatably mounted therein and can be driven relative to the rotor head (12) by means of the additional rotational mechanism, an opening (16) for the rotational unit (22) being provided in which the rotational unit is accommodated and by means of which the bearing (70) is arranged such that it is fixed relative to the rotor head (12).

Abstract: The invention relates to a rotational unit (10) for a rotor of a dual centrifuge, said rotational unit having a bearing (14) and a rotational head (24) which is connected to the bearing (14), is mounted therein such that it can rotate about an axis of rotation and can be driven relative to the rotor by an additional rotational mechanism of the centrifuge, the rotational head (24) being detachably connected to the receiving unit (40, 80) for conjoint rotation, which receiving unit comprises a sample container receptacle (60, 70, 100, 110) for at least one sample container.

Abstract: The invention relates to an apparatus for the homogenization and separation of media (10), comprising a centrifuge (40, 70) having a centrifuge rotor (14, 44, 74) which can be rotated about a motor axis (A) of a centrifuge motor (12, 42, 72) and which includes a rotor body, connected to which is at least one rotation unit (16, 48, 80) in such a way that it is additionally adapted to be rotatable about an axis of rotation of a rotation unit, which axis is different from the motor axis (A), and that it can be driven via a rotation unit drive, with means being provided which can be used to set at least two different rotation speeds of the rotation unit (16, 48, 80), and furthermore the rotation unit (16, 48, 80) has toothing (8) on its periphery by which the rotation unit (16, 48, 80) can be driven. The invention is characterized in that the rotation unit drive comprises toothing which is associated with the centrifuge motor.

Abstract: The invention relates to a medicament comprising a phospholipid component and a polysaccharide component having polysaccharides containing sulfate groups for inhibiting metastatic spread of tumors. The two components may be in same or separate preparation.

Abstract: The invention relates to a process for controlling plant pathogens comprising the application of alkylphospholipids as active substances. Further, the invention relates to the use of alkylphospholipids for controlling plant pathogens, and to an agent for controlling plant pathogens containing an effective amount of at least one alkylphospholipid.

Abstract: The invention relates to the use of acylglycerophospholipids, in particular of hydrogenated acylglycerophospholipids and of phospholipids with a high omega-3 fatty acid content, for the production of a medicament for treating symptoms concomitant with cancer, in particular for treating tumour cachexia, cancer-related problems and pain, and for the prophylaxis of tumour growth and metastasis.

Abstract: The invention relates to a method for producing lipid-based nanoparticles using a dual asymmetrical centrifuge, products produced by means of said method, kits for producing said nanoparticles using a dual asymmetrical centrifuge, and accessories for carrying out the inventive method.

Abstract: The present invention provides a process for preparing a tablet containing hydrogenated phospholipids and the tablet obtainable by such process.

Abstract: The invention relates to a method for producing liposomes which comprise as active ingredient at least one physiologically active or/and diagnostic compound, by production of a mixture of membrane-forming amphiphiles, dispersion of the mixture in water and high pressure homogenization of the dispersion until the liposomes are formed, wherein (a) the mixture is adjusted to result in a liposome preparation containing at least 20% by weight lipids, (b) the active ingredient is added to this liposome preparation and (c) the active ingredient-containing mixture is incubated with mechanical agitation until at least 10% of the liposomes have a content of the active ingredient, the temperature being controlled so that negligible phospholipid hydrolysis occurs, but diffusion is increased.

Abstract: A cationic amphiphile for facilitating transport of a biologically active molecule into a cell has the structure A-F-D, in which A is a lipid anchor, D is a head group, and F is a spacer group having the structure described herein. A method for facilitating transport of a biologically active molecule into a cell comprises preparing a lipid mixture comprising a cationic amphiphile having structure A-F-D, preparing a lipoplex by contacting the lipid mixture with a biologically active molecule; and contacting the lipoplex with a cell, thereby facilitating transport of the biologically active molecule into the cell.