Patents by Inventor Ulrich Rosentreter

Ulrich Rosentreter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted phenylaminothiazoles and use thereof
    Patent number: 8691850
    Abstract: The present application relates to novel phenylaminothiazole derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of hypertension and other cardiovascular disorders.
    Type: Grant
    Filed: August 30, 2005
    Date of Patent: April 8, 2014
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Jens-Kerim Ergüden, Gunter Karig, Ulrich Rosentreter, Barbara Albrecht, Kerstin Henninger, Joachim Hütter, Nicole Diedrichs, Peter Nell, Sabine Arndt, Walter Hübsch, Andreas Knorr, Karl-Heinz Schlemmer, Dirk Brohm
  • Substituted 2, 6-Diamino-3, 5-Dicyano-4-Aryl-Pyridines And Their Use As Adenosine-Receptor-Selective Ligands
    Publication number: 20130040992
    Abstract: The present invention relates to substituted 2,6-diamino-3,5-dicyano-4-arylpyridines of the formula (I) wherein the definitions of substituent groups R1-R7 are as provided in the specification and claims, to a pharmaceutical composition containing such a compound, to a process for preparation of such materials, and to their use as medicaments for the treatment of cardiovascular disorders and diabetes.
    Type: Application
    Filed: August 13, 2012
    Publication date: February 14, 2013
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Ulrich Rosentreter, Thomas Krämer, Andrea Vaupel, Walter Hübsch, Nicole Diedrichs, Thomas Krahn, Klaus Dembowsky, Johannes-Peter Stasch
  • Substituted 2, 6-diamino-3, 5-dicyano-4-arylpyridines and their use as adenosine-receptor-selective ligands
    Patent number: 8242281
    Abstract: The present invention relates to substituted 2,6-diamino-3,5-dicyano-4-arylpyridines of the formula (I) wherein the definitions of substituent groups R1-R7 are as provided in the specification and claims, to a pharmaceutical composition containing such a compound, to a process for preparation of such materials, and to their use as medicaments for the treatment of cardiovascular disorders and diabetes.
    Type: Grant
    Filed: December 1, 2006
    Date of Patent: August 14, 2012
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Ulrich Rosentreter, Thomas Kramer, Andrea Vaupel, Walter Hubsch, Nicole Diedrichs, Thomas Krahn, Klaus Dembowsky, Johannes-Peter Stasch
  • I-pheny 1-3,4-dihydropyrimidin-2(1H)-one derivatives and their use
    Patent number: 8173665
    Abstract: The invention relates to 4-cyanophenyl, 2-sulfanyl, 1-phenyl pyrimidine derivatives, processes for their preparation, and pharmaceutical compositions of the same. Compounds and compositions of the invention are useful in the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction, and heart failure development.
    Type: Grant
    Filed: July 27, 2009
    Date of Patent: May 8, 2012
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Heike Gielen-Haertwig, Volkhart Min-Jian Li, Ulrich Rosentreter, Karl-Heinz Schlemmer, Swen Allerheiligen, Leila Telan, Lars Bärfacker, Jörg Keldenieh, Mary F. Fitzgerald, Kevin Nash, Barbara Albrecht, Dirk Meurer
  • Heterocyclyamide-substituted imidazoles
    Patent number: 7919489
    Abstract: The invention relates to heterocyclylamide-substituted imidazoles and methods for their preparation, their use for the treatment and/or prophylaxis of diseases as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, in particular for the use as antiviral agents, especially against cytomegaloviruses.
    Type: Grant
    Filed: August 20, 2007
    Date of Patent: April 5, 2011
    Assignee: Aicuris GmbH & Co. KG
    Inventors: Holger Zimmermann, David Brueckner, Kerstin Henninger, Ulrich Rosentreter, Martin Hendrix, Joerg Keldenich, Dieter Lang, Martin Radtke, Daniela Paulsen, Armin Kern
  • Substituted 2-oxy-3,5-dicyano-4aryl-6-aminopyridines and use thereof
    Patent number: 7855219
    Abstract: This invention relates to compounds of formula (I) in which the variable groups are as defined in the text and claims. A pharmaceutical composition and methods of using these materials in treatment of various conditions are also disclosed and claimed.
    Type: Grant
    Filed: February 20, 2002
    Date of Patent: December 21, 2010
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Ulrich Rosentreter, Thomas Krämer, Andrea Vaupel, Walter Hübsch, Nicole Diedrichs, Thomas Krahn, Klaus Dembowsky, Johannes-Peter Stasch
  • Adenosine receptor selective modulators
    Patent number: 7825255
    Abstract: The invention relates to the compounds of formula (I), to a method for producing the same and to the use thereof as medicaments.
    Type: Grant
    Filed: February 28, 2002
    Date of Patent: November 2, 2010
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Ulrich Rosentreter, Thomas Krämer, Andrea Vaupel, Walter Hübsch, Nicole Diedrichs, Thomas Krahn, Klaus Dembowsky, Johannes-Peter Stásch
  • Antiviral 4-aminocarbonylamino-substituted imidazole compounds
    Patent number: 7767704
    Abstract: The invention relates to the substituted imidazoles of formula (I) and to methods for producing the same, to their use in the treatment and/or prophylaxis of diseases and to their use for producing drugs for use in the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, especially against cytomegaloviruses.
    Type: Grant
    Filed: March 11, 2005
    Date of Patent: August 3, 2010
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Holger Zimmermann, David Brueckner, Dirk Heimbach, Martin Hendrix, Kerstin Henninger, Guy Hewlett, Ulrich Rosentreter, Joerg Keldenich, Dieter Lang, Martin Radtke
  • Use of Substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines in the treatment of nausea and vomiting
    Patent number: 7709504
    Abstract: The present invention relates to the use of substituted 2-thio-3,5-dicyano-4-phenyl-6-amino-pyridines of the formula (I) wherein the terms A and R2 are herein defined, for treatment of nausea and vomiting.
    Type: Grant
    Filed: June 23, 2005
    Date of Patent: May 4, 2010
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Thomas Krahn, Wolfgang Thielemann, Ulrich Rosentreter, Nicole Diedrichs, Thomas Krämer
  • Dihydropyridine derivatives for use as human neutrophil elastase inhibitors
    Patent number: 7691854
    Abstract: The invention relates to novel dihydropyridine derivatives, of Formula (I) processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development.
    Type: Grant
    Filed: August 18, 2003
    Date of Patent: April 6, 2010
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Heike Gielen-Haertwig, Volkhart Min-Jian Li, Ulrich Rosentreter, Karl-Heinz Schlemmer, Swen Allerheiligen, Leila Telan, Lars Bärfacker, Jörg Keldenich, Mary F. Fitzgerald, Kevin Nash, Barbara Albrecht, Dirk Meurer
  • Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes
    Patent number: 7687510
    Abstract: The invention relates to novel heterocyclic derivatives, processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases.
    Type: Grant
    Filed: August 28, 2003
    Date of Patent: March 30, 2010
    Assignee: Bayer Healthcare AG
    Inventors: Heike Gielen-Haertwig, Volkhart Min-Jian Li, Ulrich Rosentreter, Karl-Heinz Schlemmer, Swen Allerheiligen, Leila Telan, Lars Bärfacker, Jörg Keldenich, Mary F. Fitzgerald, Kevin Nash, Barbara Albrecht, Dirk Meurer
  • I-PHENY 1-3,4-DIHYDROPYRIMIDIN-2(1H)-ONE DERIVATIVES AND THEIR USE
    Publication number: 20100022537
    Abstract: This invention relates to novel heterocyclic derivatives, processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development.
    Type: Application
    Filed: July 27, 2009
    Publication date: January 28, 2010
    Applicant: Bayer Healthcare AG
    Inventors: Heike Gielen-Haertwig, Volkhart Min-Jian Li, Ulrich Rosentreter, Karl-Heinz Schlemmer, Swen Allerheiligen, Leila Telan, Lars Bärfacker, Jörg Keldenieh, Mary F. Fitzgerald, Kevin Nash, Barbara Albrecht, Dirk Meurer
  • Crystal Structure of Enzyme and Uses Thereof
    Publication number: 20100003709
    Abstract: This invention relates to crystallised human neutrophil elastase and the use of its three-dimensional structure to design modulators for human neutrophil elastase.
    Type: Application
    Filed: December 13, 2005
    Publication date: January 7, 2010
    Applicant: Bayer HealthCare AG
    Inventors: Peter Reinemer, Heike Gielen-Haertwig, Ulrich Rosentreter, Volkhart Li, Axel Harrenga, Dietmar Schomburg, Karsten Niefind, Guido Hansen
  • Use of substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines for the treatment of reperfusion injury and reperfusion damage
    Publication number: 20090221649
    Abstract: The invention relates to substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines of formula (I) and their use in medicaments for the prophylaxis and/or treatment of reperfusion injury and damage.
    Type: Application
    Filed: March 11, 2006
    Publication date: September 3, 2009
    Applicant: Bayer HealthCare AG
    Inventors: Thomas Krahn, Thomas Krämer, Ulrich Rosentreter, James M. Downey, Natalia Solenkova
  • 1-phenyl1-3,4-dihydropyrimidin-2(1H)-one derivatives and their use
    Patent number: 7566723
    Abstract: The invention relates to novel 1-Phenyl-3,4-dihydropyrimidin-2(1H)-one derivatives having the formula processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development.
    Type: Grant
    Filed: August 28, 2003
    Date of Patent: July 28, 2009
    Assignee: Bayer Healthcare AG
    Inventors: Heike Gielen-Haertwig, Volkhart Min-Jian Li, Ulrich Rosentreter, Karl-Heinz Schlemmer, Swen Allerheiligen, Leila Telan, Lars Bärfacker, Jörg Keldenich, Mary F. Fitzgerald, Kevin Nash, Barbara Albrecht, Dirk Meurer
  • Substituted 2-thio-3,5-dicyano-4-aryl-6-aminopyridines and their use
    Patent number: 7504421
    Abstract: The invention relates to compounds of general formula (I), a method for the production thereof and the use thereof as pharmacologically effective substances for a broad medical indication spectrum. Furthermore, selective adenosine receptor ligands, preferably selective adenosine A1-, adenosine A2a- and/or adenosine A2b-receptor ligands are provided for the prophylaxis and/or the treatment of diseases, especially cardiovascular diseases, diseases of the urogenital region, diseases of the respiratory tract, inflammatory and neuroinflammatory diseases, diabetes, especially pancreatic diabetes, neurodegenerative diseases, pain states, cancer as well as liver fibrosis and liver cirrhosis.
    Type: Grant
    Filed: February 21, 2006
    Date of Patent: March 17, 2009
    Inventors: Ulrich Rosentreter, Rolf Henning, Marcus Bauser, Thomas Krämer, Andrea Vaupel, Walter Hübsch, Klaus Dembowsky, Olga Salcher-Schraufstatter, Johannes-Peter Stasch, Thomas Krahn, Elisabeth Perzborn
  • Substituted Phenylaminothiazoles and Use Thereof
    Publication number: 20080269300
    Abstract: The present application relates to novel phenylaminothiazole derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of hypertension and other cardiovascular disorders.
    Type: Application
    Filed: August 30, 2005
    Publication date: October 30, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Jens-Kerim Erguden, Gunter Karig, Ulrich Rosentreter, Barbara Albrecht, Kerstin Henninger, Joachim Hutter, Nicole Diedrichs, Peter Nell, Sabine Arndt, Walter Hubsch, Andreas Knorr, Karl-Heinz Schlemmer, Dirk Brohm
  • Novel Pyrimidine Derivatives and their Use
    Publication number: 20080261990
    Abstract: The present invention relates to novel pyrimidine derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular diseases, in particular dyslipidemias, arteriosclerosis, coronary heart disease, thrombosis and metabolic syndrome.
    Type: Application
    Filed: September 10, 2005
    Publication date: October 23, 2008
    Applicant: Bayer healthCare AG
    Inventors: Elke Dittrich-Wengenroth, Lars Barfacker, Axel Kretschmer, Claudia Hirth-Dietrich, Peter Ellinghaus, Martin Raabe, Hilmar Bischoff, Christian Pilger, Ulrich Rosentreter, Stephan Bartel, Klemens Lustig, Armin Kern, Dieter Lang, Marcus Bauser
  • Phenylthioacetic Acid Derivatives and Use Thereof
    Publication number: 20080255202
    Abstract: The present application relates to novel phenylthioacetic acid derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular disorders, in particular dyslipidaemias and arteriosclerosis.
    Type: Application
    Filed: March 26, 2005
    Publication date: October 16, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Hilmar Bischoff, Elke Dittrich-Wengenroth, Nils Griebenow, Axel Kretschmer, Joachim Kruger, Elisabeth Woltering, Lars Barfacker, Claudia Hirth-Dietrich, Peter Ellinghaus, Martin Raabe, Stephen Bartel, Christian Pilger, Ulrich Rosentreter, Klemens Lustig, Armin Kern, Dieter Lang
  • Use of Substituted 2-Thio-3,5-Dicyano-4-Phenyl-6-Aminopyridines In the Treatment of Nausea and Vomiting
    Publication number: 20080249133
    Abstract: The present invention relates to the use of substituted 2-thio-3,5-dicyano-4-phenyl-6-amino-pyridines of the formula (I) for production of a medicament for the prophylaxis and/or treatment of nausea and vomiting.
    Type: Application
    Filed: June 23, 2005
    Publication date: October 9, 2008
    Applicant: Bayer Healthcare AG
    Inventors: Thomas Krahn, Wolfgang Thielemann, Ulrich Rosentreter, Nicole Diedrichs, Thomas Kramer