Patents by Inventor Ulrich Steidl

Ulrich Steidl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BAX ACTIVATORS AND USES THEREOF IN CANCER THERAPY
    Publication number: 20220313665
    Abstract: Activators of BAX and their uses in cancer therapy are disclosed.
    Type: Application
    Filed: June 7, 2022
    Publication date: October 6, 2022
    Applicant: Albert Einstein College of Medicine
    Inventors: Evripidis Gavathiotis, Denis E. Reyna, Felix Kopp, Ulrich Steidl
  • INTERLEUKIN-8 FOR MAINTENANCE OF HUMAN ACUTE MYELOID LEUKEMIA AND MYELODYSPLASTIC SYNDROME AND USES THEREOF
    Publication number: 20210355501
    Abstract: Methods are disclosed for enhancing growth of a human acute myeloid leukemia (AML) sample, a human myelodysplastic syndrome (MDS) sample, a human IL-8 dependent tumor sample, human preleukemia cells, and a human preleukemia clone or subclone ex vivo or in a xenograft animal model comprising adding human interleukin-8 (hIL-8) or a hIL-8 agonist to the sample or administering hIL-8 or a hIL-8 agonist to the animal model or expressing a gene encoding hIL-8 or a hIL-8 agonist in the animal model. The invention also provides a transgenic animal that expresses a gene encoding human interleukin-8 (hIL-8) or a hIL-8 agonist, which can be used to test the effectiveness of treatments for AML, MDS and IL-8 dependent tumors.
    Type: Application
    Filed: September 23, 2019
    Publication date: November 18, 2021
    Inventors: Amit Verma, Ulrich Steidl, Britta Will, Tihomira Todorova
  • Peptides for blocking IL1RAP protein-protein interaction and uses thereof for treatment of disease
    Patent number: 11137397
    Abstract: Methods and agents are provided for inhibiting interleukin 1 receptor accessory protein (IL1RAP) protein-protein interaction to treat a broad spectrum of diseases and conditions.
    Type: Grant
    Filed: November 23, 2015
    Date of Patent: October 5, 2021
    Assignee: Albert Einstein College of Medicine
    Inventors: Ulrich Steidl, Laura Barreyro De Pujato, Mario Pujato
  • PAK1 inhibitors and uses thereof
    Patent number: 11065251
    Abstract: Methods are disclosed for treating acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) using compounds that inhibit p21 protein (Cdc42/Rac)-activated kinase (PAK1).
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: July 20, 2021
    Assignee: ALBERT EINSTEIN COLLEGE OF MEDICINE
    Inventors: Ulrich Steidl, Ashley M. Eckel, Robert F. Stanley, Boris Rogovoy, Ilya Okun
  • Identification and use of new tumor-promoting gene in hematological malignancies
    Patent number: 10941209
    Abstract: Methods are provided for diagnosing and treating a blood cancer or a myelodysplastic syndrome in a subject. Associated compositions and kits therefor are also provided.
    Type: Grant
    Filed: July 20, 2018
    Date of Patent: March 9, 2021
    Assignees: Albert Einstein College of Medicine, British Columbia Cancer Agency Branch
    Inventors: Ulrich Steidl, Christian Steidl, Ujunwa Cynthia Okoye-Okafor
  • PAK1 INHIBITORS AND USES THEREOF
    Publication number: 20200323855
    Abstract: Methods are disclosed for treating acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) using compounds that inhibit p21 protein (Cdc42/Rac)-activated kinase (PAK1).
    Type: Application
    Filed: April 3, 2017
    Publication date: October 15, 2020
    Applicant: ALBERT EINSTEIN COLLEGE OF MEDICINE, INC.
    Inventors: Ulrich Steidl, Ashley M. Eckel, Robert F. Stanley, Boris Rogovoy, Ilya Okun
  • PU.1 inhibitors
    Patent number: 10774049
    Abstract: Disclosed herein are inhibitors of PU.1. The inhibitors are useful for treating disorders associated with abnormal PU.1 levels and function.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: September 15, 2020
    Assignees: Albert Einstein College of Medicine, Georgia State University Research Foundation, Inc.
    Inventors: W. David Wilson, David W. Boykin, Gregory Poon, Ulrich Steidl, Iléana Anthony-Debré
  • PU.1 INHIBITORS
    Publication number: 20190112276
    Abstract: Disclosed herein are inhibitors of PU.1. The inhibitors are useful for treating disorders associated with abnormal PU.1 levels and function.
    Type: Application
    Filed: December 20, 2018
    Publication date: April 18, 2019
    Applicants: ALBERT EINSTEIN COLLEGE OF MEDICINE, INC., GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: W. David Wilson, David W. Boykin, Gregory Poon, Ulrich Steidl, Iléana Anthony-Debré
  • IDENTIFICATION AND USE OF NEW TUMOR-PROMOTING GENE IN HEMATOLOGICAL MALIGNANCIES
    Publication number: 20180371105
    Abstract: Methods are provided for diagnosing and treating a blood cancer or a myelodysplastic syndrome in a subject. Associated compositions and kits therefor are also provided.
    Type: Application
    Filed: July 20, 2018
    Publication date: December 27, 2018
    Inventors: Ulrich Steidl, Christian Steidl, Ujunwa Cynthia Okoye-Okafor
  • PEPTIDES FOR BLOCKING IL1RAP PROTEIN-PROTEIN INTERACTION AND USES THEREOF FOR TREATMENT OF DISEASE
    Publication number: 20180275123
    Abstract: Methods and agents are provided for inhibiting interleukin 1 receptor accessory protein (IL1RAP) protein-protein interaction to treat a broad spectrum of diseases and conditions.
    Type: Application
    Filed: November 23, 2015
    Publication date: September 27, 2018
    Applicant: Albert Einstein College of Medicine, Inc
    Inventors: Ulrich Steidl, Laura Barreyro De Pujato, Mario Pujato
  • IDENTIFICATION AND USE OF NEW TUMOR-PROMOTING GENE IN HEMATOLOGICAL MALIGNANCIES
    Publication number: 20150329643
    Abstract: Methods are provided for diagnosing and treating a blood cancer or a myelodysplastic syndrome in a subject. Associated compositions and kits therefor are also provided.
    Type: Application
    Filed: November 15, 2013
    Publication date: November 19, 2015
    Applicant: ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY
    Inventors: Ulrich Steidl, Christian Steidl, Cynthia Ujunwa Okoye-Okafor