Abstract: A system for the extracorporeal elimination of carbon monoxide, includes at least one pump and a gas exchange chamber, wherein the at least one pump can be connected to the blood circulatory system of a person by way of a first tube section connectable to a cannula and is connected to a gas exchange chamber via a second tube section, wherein the system is configured to transfer blood, via the first tube section, from the blood circulatory system of the person by way of at least one pump into the gas exchange chamber, and to return the blood from the gas exchange chamber to the blood circulatory system of the person via the same first tube section.

Abstract: The invention relates to a method for producing a device for material exchange between two mediums, in which at least one mat of semipermeable hollow fibres (3) is wound onto a winding core (2), which has at least one core opening (2a) in its outer surface for a first in- or out-flowing medium, and the winding core (2) is arranged in an axially extending housing (1) having at least one housing opening (1a) for the first in- or out-flowing medium and the axial end regions of the housing (1) are sealed by an adhesive (4) arranged around the hollow fibres (3), wherein at least one chamber region (5) surrounding the hollow fibres (3) is formed via the adhesion between the axial end regions (1b, 1c) of the housing (1) and between the winding core (2) and the housing (1), through which chamber region the first medium can flow via the core opening (2a) and the housing opening (1a), wherein the axial distance between the core opening (2a) and the housing opening (1a) is adjusted to a desired value of multiple possibl

Abstract: A system for the extracorporeal elimination of carbon monoxide, includes at least one pump and a gas exchange chamber, wherein the at least one pump can be connected to the blood circulatory system of a person by way of a first tube section connectable to a cannula and is connected to a gas exchange chamber via a second tube section, wherein the system is configured to transfer blood, via the first tube section, from the blood circulatory system of the person by way of at least one pump into the gas exchange chamber, and to return the blood from the gas exchange chamber to the blood circulatory system of the person via the same first tube section.

Abstract: The invention relates to a rotary piston pump, in particular for pumping blood, comprising a piston rotor (1) which has particularly two or three faces when seen in cross-section, which is mounted in a piston chamber (2) and eccentrically rotates, the piston rotor (1) having in its interior a plurality of magnetically interacting elements (4, 4a, 4b), in particular permanent magnets and/or coils, and being driven by the magnetic interaction of these elements (4, 4a, 4b) with at least one moving magnetic field.

Abstract: An oxygenator module for gas exchange between blood and a gas in an extracorporeal lung support system, with several layers of semipermeable, gas-perfusable hollow fibers, wherein the hollow fibers of one of the layers are oriented at an angle of rotation about a central longitudinal axis of the oxygenator module with respect to the hollow fibers of another one of the layers, and with a potting which extends along the central longitudinal axis and in which the hollow fibers are fixed, wherein the potting defines a cavity that extends along the central longitudinal axis and in which the hollow fibers are arranged and which is blood-perfusable in the direction of the central longitudinal axis, wherein the potting has an essentially circular inner sheath surface that limits the cavity radially outward; as well as a method for producing the oxygenator module.

Abstract: The present disclosure relates to a method for bonding a polyurethane polymer to a substrate using a multi-layered adhesion approach. Steps of the method include A) selecting a polyurethane polymer to be bonded to the substrate (100); B) depositing an SiO2 layer (200) onto the substrate (100); C) contacting the SiO2 layer (200) with a hydroxysilane compound, thereby forming a first adhesive layer (300) bonded to the SiO2 layer (200); D) contacting the first adhesive layer (300) with a urethane (meth)acrylate compound, thereby forming a second adhesive layer (400) bonded to the first adhesive layer (300); E) contacting the second adhesive layer (400) with a polyurethane (meth)acrylate compound, thereby forming a third adhesive layer (500) bonded to the second adhesive layer (400); F) contacting the third adhesive layer (500) with the polyurethane polymer selected in step A); G) solidifying the polyurethane polymer of step F).

Abstract: The invention relates to a method of controlling the speed of a ventricular assist device, in particular the rotational speed of a rotary blood pump, wherein at least temporarily the speed of the device is modulated around a mean speed and a response of the native heart to this modulation is measured to determine the ventricular function/contractile state of the heart, in particular to determine whether the aortic valve opens and closes at the instant mean speed, and the mean speed is set, in particular a new mean speed is set in dependence of the measured response. The invention furthermore relates to a device performing the method.

Abstract: The invention relates to an impeller (1) of a centrifugal pump apparatus, in particular of a blood pump apparatus, comprising a discoidal body (1) rotatable around an axis (2) of rotation, the body (1) comprising an upper surface (3), a lower surface (4), a central channel (5) extending in the direction of the axis (2) of rotation between the upper and lower surface (3, 4) for guiding fluid, in particular blood through the body (1) in axial direction when the body (1) is rotated in a pump chamber of a pump and several blades (6) supported by the upper surface (3) for pumping fluid, in particular blood, when the body (1) is rotated in a pump chamber of a pump, several spiral grooves (7) in the lower surface (4), each groove (7) having a bottom (7a) and two sidewalls (7b, 7c) and being open in an axial direction, merging into a circumferential surface (8) of the body (1) and extending from this circumferential surface (8) to the central channel (5) at least for providing a pumping action of fluid, in particular

Abstract: The invention relates to a blood cannula for discharging blood into a vessel, in particular aortic cannula for discharging blood into an aortic arch during heart-bypass surgery, comprising a tubular body (1), the tubular body having a straight part at the proximal end (2) and a bent part at the distal end (3) leading into an outlet opening (5), wherein the distal end (3), in particular the bent part has an increasing cross section in the direction of blood flow (B).

Abstract: The invention relates to a rotary piston pump, in particular for pumping blood, comprising a piston rotor (1) which has particularly two or three faces when seen in cross-section, which is mounted in a piston chamber (2) and eccentrically rotates, the piston rotor (1) having in its interior a plurality of magnetically interacting elements (4, 4a, 4b), in particular permanent magnets and/or coils, and being driven by the magnetic interaction of these elements (4, 4a, 4b) with at least one moving magnetic field.

Abstract: An axial-flow blood pump has a rotatable impeller assembly rotatable about an axis and itself having a radially projecting blade and permanent magnets, A stationary stator assembly has stator windings interacting with the permanent magnets and a bearing system supporting the rotatable impeller assembly for rotation about the axis relative to the stator assembly. A stent implantable into a blood vessel is connected to ends of supports for coaxially mounting the stator assembly carrying the impeller assembly in the stent.

Abstract: An oxygenator module for gas exchange between blood and a gas in an extracorporeal lung support system, with several layers of semipermeable, gas-perfusable hollow fibers, wherein the hollow fibers of one of the layers are oriented at an angle of rotation about a central longitudinal axis of the oxygenator module with respect to the hollow fibers of another one of the layers, and with a potting which extends along the central longitudinal axis and in which the hollow fibers are fixed, wherein the potting defines a cavity that extends along the central longitudinal axis and in which the hollow fibers are arranged and which is blood-perfusable in the direction of the central longitudinal axis, wherein the potting has an essentially circular inner sheath surface that limits the cavity radially outward: as well as a method for producing the oxygenator module.

Abstract: The invention relates to an impeller (1) of a centrifugal pump apparatus, in particular of a blood pump apparatus, comprising a discoidal body (1) rotatable around an axis (2) of rotation, the body (1) comprising an upper surface (3), a lower surface (4), a central channel (5) extending in the direction of the axis (2) of rotation between the upper and lower surface (3, 4) for guiding fluid, in particular blood through the body (1) in axial direction when the body (1) is rotated in a pump chamber of a pump and several blades (6) supported by the upper surface (3) for pumping fluid, in particular blood, when the body (1) is rotated in a pump chamber of a pump, several spiral grooves (7) in the lower surface (4), each groove (7) having a bottom (7a) and two sidewalls (7b, 7c) and being open in an axial direction, merging into a circumferential surface (8) of the body (1) and extending from this circumferential surface (8) to the central channel (5) at least for providing a pumping action of fluid, in particular

Abstract: The invention relates to a blood cannula for discharging blood into a vessel, in particular aortic cannula for discharging blood into an aortic arch during heart-bypass surgery, comprising a tubular body (1), the tubular body having a straight part at the proximal end (2) and a bent part at the distal end (3) leading into an outlet opening (5), wherein the distal end (3), in particular the bent part has an increasing cross section in the direction of blood flow (B).

Abstract: The invention relates to a method of controlling the speed of a ventricular assist device, in particular the rotational speed of a rotary blood pump, wherein at least temporarily the speed of the device is modulated around a mean speed and a response of the native heart to this modulation is measured to determine the ventricular function/contractile state of the heart, in particular to determine whether the aortic valve opens and closes at the instant mean speed, and the mean speed is set, in particular a new mean speed is set in dependence of the measured response. The invention furthermore relates to a device performing the method.

Abstract: The invention relates to an axial flow blood pump device comprising an integrated electromagnetic drive with a stationary stator assembly and a rotatable impeller assembly, wherein the stationary stator assembly at least comprises stator windings (3) and a bearing system (4) supporting the rotatable impeller assembly, the impeller assembly comprising at least one blade (9) and permanent magnets (10) interacting with the stator windings (3), wherein the stationary stator assembly comprises supporting elements (8) for mounting, in particular coaxially mounting the device in the interior of an anchoring system (7) being implantable into a vessel.

Abstract: A cardiac function variation evaluation apparatus includes: a continuous flow type auxiliary artificial heart 20 connected to a ventricle (10A); a pressure sensor 30 for detecting ventricle (10A) internal pressure; and means (a personal computer 40) for evaluating contractile variation of the ventricle, to which the auxiliary artificial heart 20 is connected, based on internal area APMp of a closed-loop of a relationship between the ventricle internal pressure detected by the pressure sensor 30 and a consumption power of the auxiliary artificial heart 20. Thus, the contractile variation of the ventricle, to which an auxiliary artificial heart is connected, can be continuously evaluated not by use of an ultrasonic echo apparatus or a conductance catheter but by use of a non-invasive method.

Abstract: The invention relates to a blood withdrawal cannula (4) for connecting a pump (2) assisting or replacing activity of the heart to the inner volume of a heart ventricle (1), in particular the left ventricle. At the end thereof that is located in the ventricle the cannula has a pressure sensor (7a, 7b) for measuring the ventricle pressure and/or ventricle pressure differences and at the same end of the cannula has a volume sensor (3a, 3b, 5, 6) for measuring the volume and/or volume changes of the ventricle (1) in at least a partial region of the ventricle. The invention further relates to a measuring device for monitoring the ventricle contractions and/or the function of a pump replacing or assisting activity of the heart. The measuring device can be/is connected to the pressure sensor (7a, 7b) and to the volume sensor of a blood withdrawal cannula according to any one of the preceding claims and is designed to detect pressure changes and volume changes of a ventricle (1) as the heart is beating.

Abstract: An exchanger device for transferring mass and/or energy between a first medium and a second medium includes a chamber having a first inlet and first outlet of the first medium and through which the first medium can flow. The chamber is equipped with at least one, preferably a plurality, of one mass- and/or energy-permeable exchanger hollow fibers connected at one end to a second inlet and at the other end to a second outlet of the second medium. The second medium can flow through the fiber(s) and the first medium can flow around the fiber(s). The chamber is equipped with at least one pump element for displacing the first medium in and out of the chamber in a pulsing manner. The pump element has an elastically deformable element, is connected to a third inlet of a third medium used as a driving medium, and is expandable by the third medium.

Abstract: The invention relates to an electrical linear drive, in particular for a pump system of an artificial heart, with a movable part and a stationary part, wherein the stationary part is formed by a permanent magnet arrangement and the movable part is formed by a coil arrangement, or vice versa, and wherein the coil arrangement and the permanent magnet arrangement can be moved to and fro relative to each other in an axial direction by means of current passed through the coil arrangement. The invention further relates to an electrical linear drive of this kind in which the permanent magnet arrangement is designed as a stack of frame-shaped, in particular ring-shaped magnets, which are magnetized alternately radially and axially in the axial direction, such that the magnetic field is strengthened on one side of the frame.