Patents by Inventor Ulrik B. Nielson

Ulrik B. Nielson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of high-throughput screening for internalizing antibodies
    Patent number: 7045283
    Abstract: This invention provides methods of identifying ligands that are internalized into a cell. The methods typically involve i) contacting the cell with a reporter non-covalently coupled to a ligand; ii) dissociating the reporter from the ligand and removing dissociated reporter from the surface of the cell; and iii) detecting the reporter within said cell (if any is present) where the presence of the reporter within said cell indicates that the ligand binds to an internalizing receptor and is internalized.
    Type: Grant
    Filed: October 16, 2001
    Date of Patent: May 16, 2006
    Assignee: The Regents of the University of California
    Inventors: James D. Marks, Ulrik B. Nielson, Dimitri B. Kirpotin