Patents by Inventor Ulrike Kufner-Muhl

Ulrike Kufner-Muhl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acylamino-substituted hetrazepines
    Patent number: 5753647
    Abstract: A hetrazepine of the formula given below and a pharmaceutical composition comprising a therapeutically effective amount of the hetrazepine and a pharmaceutically acceptable inert carrier are disclosed and are useful in treating disease in a warm-blooded animal induced by endogenously formed PAF; ##STR1## wherein the substituents are defined herein.
    Type: Grant
    Filed: December 5, 1994
    Date of Patent: May 19, 1998
    Assignee: Boehringer Ingelheim KG
    Inventors: Karl-Heinz Weber, Werner Stransky, Ulrike Kufner-Muhl, Hubert Heuer, Franz Birke
  • Asymmetrically substituted xanthines
    Patent number: 5719279
    Abstract: Xanthine derivatives of formula ##STR1## wherein R.sub.1 is hydrogen, alkyl or alkynyl,R.sub.2 is different and is alkyl, alkynyl, phenyl-alkylene, phenyl alkenylene, cycloalkyl, inter alia,R.sub.3 is cycloalkyl, phenyl, norbornane, inter alia andR.sub.4 is hydrogen, methyl, benzyl, inter alia.
    Type: Grant
    Filed: June 11, 1996
    Date of Patent: February 17, 1998
    Assignee: Boehringer Ingelheim KG
    Inventors: Ulrike Kufner-Muhl, Helmut Ensinger, Joachim Mierau, Franz Josef Kuhn, Erich Lehr, Enzio Muller
  • Hetrazepinoid amides
    Patent number: 5698552
    Abstract: The present invention relates to thienodiazepines of formula Ib: ##STR1## wherein U, V, R.sub.5, R.sub.6 and R.sub.7 are as defined herein. This invention also relates to processes for preparing these thienodiazepines and their use in pharmaceutical compositions with PAF-antagonistic activity.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: December 16, 1997
    Assignee: Boehringer Ingelheim KG
    Inventors: Karl-Heinz Weber, Werner Stransky, Ulrike Kufner-Muhl, Hubert Heuer, Franz Birke, Wolf-Dietrich Bechtel
  • Xanthine derivatives with adenosine-antagonistic activity
    Patent number: 5696124
    Abstract: The invention relates to new xanthine derivatives of general formula I, processes for preparing them and their use as pharmaceutical compositions.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: December 9, 1997
    Assignee: Boehringer Ingelheim Kg
    Inventors: Ulrike Kufner-Muhl, Karl-Heinz Weber, Gerhard Waither, Werner Stransky, Helmut Ensinger, Gunter Schingnitz, Franz Josef Kuhn, Erich Lehr
  • Bornyl xanthine derivatives with adenosine-antagonistic activity
    Patent number: 5688802
    Abstract: The invention relates to new xanthine derivatives of general formula I, processes for preparing them and their use as pharmaceutical compositions.
    Type: Grant
    Filed: June 14, 1996
    Date of Patent: November 18, 1997
    Assignee: Boehringer Ingelheim KG
    Inventors: Ulrike Kufner-Muhl, Karl-Heinz Weber, Gerhard Walther, Werner Stransky, Helmut Ensinger, Gunter Schingnitz, Franz Josef Kuhn, Erich Lehr
  • Process for preparing xanthine derivatives, in particular 1,3-dipropyl-8-(3-oxocyclopentyl)-xanthine
    Patent number: 5675005
    Abstract: This invention relates to a process for preparing xanthine derivatives of formula I: ##STR1## characterized in that a uracil derivative of formula A or B ##STR2## is dissolved in a suitable organic-aqueous solvent and cyclized in the presence of LiOH.
    Type: Grant
    Filed: March 7, 1995
    Date of Patent: October 7, 1997
    Assignee: Boehringer Ingelheim KG
    Inventors: Ulrike Kufner-Muhl, Sven Luttke
  • 8-substituted 1,3-dialiphaticxanthine derivatives
    Patent number: 5641784
    Abstract: New xanthine compounds of formula I: ##STR1## wherein the substituents are defined herein, which xanthines are useful as adenosine antagonists.
    Type: Grant
    Filed: December 22, 1994
    Date of Patent: June 24, 1997
    Assignee: Boehringer Ingelheim KG
    Inventors: Ulrike Kufner-Muhl, Werner Stransky, Gerhard Walther, deceased, Karl-Heinz Weber, Helmut Ensinger, Franz Josef Kuhn, Gunter Schingnitz, Erich Lehr
  • Xanthine derivatives with adenosine-antagonistic activity
    Patent number: 5532368
    Abstract: Xanthines of the formula I ##STR1## wherein R.sub.1 is a C.sub.1 -C.sub.4 alkyl group:R.sub.2 is a C.sub.1 -C.sub.4 alkyl group;R.sub.3 tetrahydropyran-4-yl or 1,3-dithiolan or;R.sub.3 represents one of the groups of formula ##STR2## and pharmaceutically acceptable acid addition salts thereof. These are adenosine antagonists, capable of acting as cholinomimetics, useful for the treatment of CNS disorders such as senile dementia and Alzheimer's disease.
    Type: Grant
    Filed: July 27, 1993
    Date of Patent: July 2, 1996
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Ulrike Kufner-Muhl, Karl-Heinz Weber, Gerhard Walther, Werner Stransky, Helmut Ensinger, Gunter Schingnitz, Franz J. Kuhn, Erich Lehr
  • Process for preparing 1,3-dipropyl-8-(3-oxocyclopentyl)-xanthine
    Patent number: 5175291
    Abstract: A process for preparing 1,3-dipropyl-8-(3-oxocyclopentyl)-xanthine.
    Type: Grant
    Filed: April 25, 1991
    Date of Patent: December 29, 1992
    Assignee: Boehringer Ingelheim KG
    Inventor: Ulrike Kufner-Muhl