Patents by Inventor Uma Sampathkumaran

Uma Sampathkumaran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11857632
    Abstract: A versatile drug delivery system comprised of plant-based nanocellulose can be used for providing high loading and extended release for virtually any drug. This system is made from nanocrystalline cellulose chemically cross-linked to form a hydrogel. This versatile hydrogel-based drug delivery system can be functionalized to support extended release of oral dosing, relieving patient burden and increasing quality of life.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: January 2, 2024
    Assignee: INNOSENSE LLC
    Inventors: Anamika Ray, Cheyann Wetteland, Harini Madakashira, Joseph Kessler, Uma Sampathkumaran
  • Patent number: 11776705
    Abstract: A method of providing alpha particle emitters and materials suitable for use in generating the alpha particles for medical treatment is disclosed. Metal oxide targets, preferentially Bi2O3 pellets and Bi2O3 coatings on metallic or metal oxide substrates are formed. The targets placed in a heated vacuum chamber subjecting to irradiation using a 6Li beam at an elevated temperature below the melting point of the target generate a radioactive gas, such as 211Rn, the radioactive gas is carried by an inert gas which is delivered a carrier for, such as a carbon column or oil for delivery to a treatment facility. The radioactive gas such as 211Rn generates 211At, which has a useable half-life of at least about 14 hours, in turn releases alpha particles which are effective for use in medical procedures.
    Type: Grant
    Filed: January 16, 2021
    Date of Patent: October 3, 2023
    Assignee: INNOSENSE LLC
    Inventors: Uma Sampathkumaran, Raymond Winter, Harini Madakashira
  • Patent number: 11760888
    Abstract: Materials are disclosed for the safe sequestration and removal of hazardous contaminants from a surface. The materials can be sprayed, rolled, painted, brushed or dip coated onto any surface and allowed to dry and/or cure at room temperature or drying/curing can be accelerated by the application of heat to form a coating that entraps the contaminant therein. The coating and the entrapped contaminant can then peeled from the surface and safely disposed of to minimize hazardous waste. The coating includes a colorimetric additive that is specific to the contaminant, the coating and the contaminant producing a visual indication of contamination.
    Type: Grant
    Filed: May 28, 2021
    Date of Patent: September 19, 2023
    Assignee: INNOSENSE LLC
    Inventors: Uma Sampathkumaran, Kevin H. Yu, Raymond Winter
  • Patent number: 11621457
    Abstract: Methods for producing ceramic films Yttria Stabilized Zirconia (3YSZ) and aluminum titanate (Al2TiO5), and the physical properties of these films are described. The films produced have thicknesses and integrity suitable for handling and corrosion resistance to electrolytes, porosity, ion permeability and electrical resistivity suitable for use as separators between positive and negative layers for forming electrical batteries, particularly lithium batteries.
    Type: Grant
    Filed: January 10, 2022
    Date of Patent: April 4, 2023
    Assignee: INNOSENSE LLC
    Inventors: Raymond Winter, Maksudul M. Alam, Uma Sampathkumaran, John Abolencia
  • Patent number: 11245157
    Abstract: Methods for producing ceramic films Yttria Stabilized Zirconia (3YSZ) and aluminum titanate (Al2TiO5), and the physical properties of these films are described. The films produced have thicknesses and integrity suitable for handling and corrosion resistance to electrolytes, porosity, ion permeability and electrical resistivity suitable for use as separators between positive and negative layers for forming electrical batteries, particularly lithium batteries.
    Type: Grant
    Filed: February 28, 2019
    Date of Patent: February 8, 2022
    Assignee: INNOSENSE LLC
    Inventors: Raymond Winter, Maksudul M. Alam, Uma Sampathkumaran, John Abolencia
  • Patent number: 11021615
    Abstract: Materials are disclosed for the safe sequestration and removal of hazardous contaminants from a surface. The materials can be sprayed, rolled, painted, brushed or dip coated onto any surface and allowed to dry and/or cure at room temperature or drying/curing can be accelerated by the application of heat to form a coating that entraps the contaminant therein. The coating and the entrapped contaminant can then peeled from the surface and safely disposed of to minimize hazardous waste. The coating includes a colorimetric additive that is specific to the contaminant, the coating and the contaminant producing a visual indication of contamination.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: June 1, 2021
    Assignee: INNOSENSE LLC
    Inventors: Uma Sampathkumaran, Kevin H. Yu, Raymond Winter
  • Publication number: 20200280037
    Abstract: Methods for producing ceramic films Yttria Stabilized Zirconia (3YSZ) and aluminum titanate (Al2TiO5), and the physical properties of these films are described. The films produced have thicknesses and integrity suitable for handling and corrosion resistance to electrolytes, porosity, ion permeability and electrical resistivity suitable for use as separators between positive and negative layers for forming electrical batteries, particularly lithium batteries.
    Type: Application
    Filed: February 28, 2019
    Publication date: September 3, 2020
    Inventors: Raymond Winter, Maksudul M. Alam, Uma Sampathkumaran, John Abolencia
  • Patent number: 10435584
    Abstract: The present invention relates to hydrophilic anti-fog coatings. In particular, the coatings use two types of nanoscale particles, colloidal silica and porous organosilicate micelles, in a polyurethane matrix. The invention is an anti-fog coating for optically clear substrates (polycarbonate, polyurethane, nylon, polyester and other clear plastics) without the need for a primer and glass substrates with an additional primer layer, comprising monosized colloidal silica nanoparticles and porous organosilicate micelles in a polyurethane matrix. The silica is preferably 1-5% by weight and the micelles are loaded at 0.1 to 10% volume percentage by volume. The polyurethane prepolymer is dissolved at 10-40% by weight in a mixture of tertiary amyl alcohol and diacetone alcohol to customize for dip, flow or spray coating processes.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: October 8, 2019
    Assignee: INNOSENSE LLC
    Inventors: Uma Sampathkumaran, Kevin H. Yu, Corey M. Selman
  • Publication number: 20180364188
    Abstract: A sensor array comprising multiple discrete sensors for providing detection and prognosis of various diseases. The array is made up of multiple discrete sensors, each of which has a first and a second noble metal electrode on a silicon substrate, said electrodes separated by a gap. An electrically conductive pathway across the gap between the first and second noble electrodes is provided by a nano-network of functionalized polymer nanowires or carbon nanotubes (SWNTs) the arrangement providing a sensor. The multiple discrete sensors comprise a reference cell and multiple detection sensors functionalized using a panel of capture molecules to detect the same or different diseases or biological functions.
    Type: Application
    Filed: May 24, 2018
    Publication date: December 20, 2018
    Inventors: Anamika Ray, Yifan Tang, Maksudul M. Alam, Jeffrey Paul, Corey Selman, Uma Sampathkumaran
  • Publication number: 20180202964
    Abstract: The present invention relates to methods of forming modular chemiresistive sensors. The sensors preferably have two gold or platinum electrodes mounted on a silicon substrate with the electrodes connected to a power source and are separated by a gap of 0.5 to 4.0 ?m. Functionalized polymer nanowire or carbon nanotube span the gap between the electrodes and connect the electrodes electrically. The electrodes are further connected to a circuit board having a processor and data storage, where the processor measures current and voltage values between the electrodes and compares the current and voltage values with current and voltages values stored in the data storage and assigned to particular concentrations of a pre-determined substances.
    Type: Application
    Filed: December 21, 2017
    Publication date: July 19, 2018
    Inventors: Maksudul M. Alam, Uma Sampathkumaran
  • Publication number: 20180100085
    Abstract: The present invention relates to hydrophilic anti-fog coatings. In particular, the coatings use two types of nanoscale particles, colloidal silica and porous organosilicate micelles, in a polyurethane matrix. The invention is an anti-fog coating for optically clear substrates (polycarbonate, polyurethane, nylon, polyester and other clear plastics) without the need for a primer and glass substrates with an additional primer layer, comprising monosized colloidal silica nanoparticles and porous organosilicate micelles in a polyurethane matrix. The silica is preferably 1-5% by weight and the micelles are loaded at 0.1 to 10% volume percentage by volume. The polyurethane prepolymer is dissolved at 10-40% by weight in a mixture of tertiary amyl alcohol and diacetone alcohol to customize for dip, flow or spray coating processes.
    Type: Application
    Filed: December 11, 2017
    Publication date: April 12, 2018
    Inventors: Uma Sampathkumaran, Kevin H. Yu, Corey M. Selman
  • Patent number: 9896772
    Abstract: The present invention relates to a modular chemiresistive sensor. In particular, a modular chemiresistive sensor for hypergolic fuel and oxidizer leak detection, carbon dioxide monitoring and detection of disease biomarkers. The sensor preferably has two gold or platinum electrodes mounted on a silicon substrate where the electrodes are connected to a power source and are separated by a gap of 0.5 to 4.0 ?M. A polymer nanowire or carbon nanotube spans the gap between the electrodes and connects the electrodes electrically. The electrodes are further connected to a circuit board having a processor and data storage, where the processor can measure current and voltage values between the electrodes and compare the current and voltage values with current and voltage values stored in the data storage and assigned to particular concentrations of a pre-determined substance such as those listed above or a variety of other substances.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: February 20, 2018
    Assignee: INNOSENSE LLC
    Inventors: Maksudul M. Alam, Uma Sampathkumaran
  • Patent number: 9840639
    Abstract: The present invention relates to hydrophilic anti-fog coatings. In particular, the coatings use two types of nanoscale particles, colloidal silica and porous organosilicate micelles, in a polyurethane matrix. The invention is an anti-fog coating for optically clear substrates (polycarbonate, polyurethane, nylon, polyester and other clear plastics) without the need for a primer and glass or oxide substrates with an additional primer layer, comprising monosized colloidal silica nanoparticles and porous organosilicate micelles in a polyurethane matrix. The silica is preferably 1-5% by weight and the micelles are loaded at 0.1 to 10% volume percentage by volume.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: December 12, 2017
    Assignee: INNOSENSE LLC
    Inventors: Uma Sampathkumaran, Kevin H. Yu, Corey M. Selman
  • Publication number: 20170342277
    Abstract: Materials are disclosed for the safe sequestration and removal of hazardous contaminants from a surface. The materials can be sprayed, rolled, painted, brushed or dip coated onto any surface and allowed to dry and/or cure at room temperature or drying/curing can be accelerated by the application of heat to form a coating that entraps the contaminant therein. The coating and the entrapped contaminant can then peeled from the surface and safely disposed of to minimize hazardous waste. The coating includes a colorimetric additive that is specific to the contaminant, the coating and the contaminant producing a visual indication of contamination.
    Type: Application
    Filed: May 31, 2017
    Publication date: November 30, 2017
    Inventors: Uma Sampathkumaran, Kevin H. Yu, Raymond Winter
  • Patent number: 9310258
    Abstract: The present disclosure relates to a dosimeter for measuring exposure to heat over time in combination with peak temperature indicators and reversible temperature indicators. The preferred temperature indicator tag is credit card sized and comprises four time-temperature dosimeters. Each dosimeter has a wick in contact with a separate reservoir containing a mix of a colored dye, a wax and an amorphous polymer to indicate a distinct temperature range when the mix melts. The wicks are preferably made of porous paper with a pore size around 8 microns to allow for proper capillary action along its length. An adhesive, except where each wick contacts its respective reservoir and at a vent, preferably seals each wick. The tag preferably has a plurality of peak temperature indicators where each indicator has a blend of a dye, a wax and a polymer for a temperature indication range. The tag also preferably has a plurality of reversible temperature sensors.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: April 12, 2016
    Inventors: Corey M. Selman, Uma Sampathkumaran
  • Publication number: 20150344725
    Abstract: The present invention relates to hydrophilic anti-fog coatings. In particular, the coatings use two types of nanoscale particles, colloidal silica and porous organosilicate micelles, in a polyurethane matrix. The invention is an anti-fog coating for optically clear substrates (polycarbonate, polyurethane, nylon, polyester and other clear plastics) without the need for a primer and glass or oxide substrates with an additional primer layer, comprising monosized colloidal silica nanoparticles and porous organosilicate micelles in a polyurethane matrix. The silica is preferably 1-5% by weight and the micelles are loaded at 0.1 to 10% volume percentage by volume.
    Type: Application
    Filed: March 20, 2015
    Publication date: December 3, 2015
    Inventors: Corey M. Selman, Kevin H. Yu, Uma Sampathkumaran
  • Publication number: 20150260668
    Abstract: The present invention relates to a modular chemiresistive sensor. In particular, a modular chemiresistive sensor for hypergolic fuel and oxidizer leak detection, carbon dioxide monitoring and detection of disease biomarkers. The sensor preferably has two gold or platinum electrodes mounted on a silicon substrate where the electrodes are connected to a power source and are separated by a gap of 0.5 to 4.0 ?M. A polymer nanowire or carbon nanotube spans the gap between the electrodes and connects the electrodes electrically. The electrodes are further connected to a circuit board having a processor and data storage, where the processor can measure current and voltage values between the electrodes and compare the current and voltage values with current and voltage values stored in the data storage and assigned to particular concentrations of a pre-determined substance such as those listed above or a variety of other substances.
    Type: Application
    Filed: March 13, 2015
    Publication date: September 17, 2015
    Inventors: Maksudul M. Alam, Uma Sampathkumaran
  • Publication number: 20150168225
    Abstract: The present disclosure relates to a dosimeter for measuring exposure to heat over time in combination with peak temperature indicators and reversible temperature indicators. The preferred temperature indicator tag is credit card sized and comprises four time-temperature dosimeters. Each dosimeter has a wick in contact with a separate reservoir containing a mix of a colored dye, a wax and an amorphous polymer to indicate a distinct temperature range when the mix melts. The wicks are preferably made of porous paper with a pore size around 8 microns to allow for proper capillary action along its length. An adhesive, except where each wick contacts its respective reservoir and at a vent, preferably seals each wick. The tag preferably has a plurality of peak temperature indicators where each indicator has a blend of a dye, a wax and a polymer for a temperature indication range. The tag also preferably has a plurality of reversible temperature sensors.
    Type: Application
    Filed: February 5, 2015
    Publication date: June 18, 2015
    Applicant: INNOSENSE, LLC
    Inventors: Corey M. Selman, Uma Sampathkumaran
  • Patent number: 8979361
    Abstract: The present disclosure relates to a dosimeter for measuring exposure to heat over time in combination with peak temperature indicators and reversible temperature indicators. The preferred temperature indicator tag is credit card sized and comprises four time-temperature dosimeters. Each dosimeter has a wick in contact with a separate reservoir containing a mix of a colored dye, a wax and an amorphous polymer to indicate a distinct temperature range when the mix melts. The wicks are preferably made of porous paper with a pore size around 8 microns to allow for proper capillary action along its length. An adhesive, except where each wick contacts its respective reservoir and at a vent, preferably seals each wick. The tag preferably has a plurality of peak temperature indicators where each indicator has a blend of a dye, a wax and a polymer for a temperature indication range. The tag also preferably has a plurality of reversible temperature sensors.
    Type: Grant
    Filed: April 30, 2012
    Date of Patent: March 17, 2015
    Assignee: InnoSense LLC
    Inventors: Corey M. Selman, Uma Sampathkumaran
  • Publication number: 20130287059
    Abstract: The present disclosure relates to a dosimeter for measuring exposure to heat over time in combination with peak temperature indicators and reversible temperature indicators. The preferred temperature indicator tag is credit card sized and comprises four time-temperature dosimeters. Each dosimeter has a wick in contact with a separate reservoir containing a mix of a colored dye, a wax and an amorphous polymer to indicate a distinct temperature range when the mix melts. The wicks are preferably made of porous paper with a pore size around 8 microns to allow for proper capillary action along its length. An adhesive, except where each wick contacts its respective reservoir and at a vent, preferably seals each wick. The tag preferably has a plurality of peak temperature indicators where each indicator has a blend of a dye, a wax and a polymer for a temperature indication range. The tag also preferably has a plurality of reversible temperature sensors.
    Type: Application
    Filed: April 30, 2012
    Publication date: October 31, 2013
    Inventors: Corey M. Selman, Uma Sampathkumaran