Patents by Inventor UmaShanker Sampath

UmaShanker Sampath has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYMERIC NUCLEOSIDE PRODRUGS
    Publication number: 20100081627
    Abstract: Disclosed are polymeric compounds which are useful as prodrugs, comprising a chain of monomeric nucleosides, nucleoside analogs or abasic nucleosides, wherein at least one of the nucleosides or nucleoside analogs or a heterocyclic derivative thereof is pharmaceutically active and the nucleosides, nucleoside analogs or abasic nucleosides are linked by a phosphodiester group, a phosphorothioate group or an H—, alkyl or alkenyl phosphonate group.
    Type: Application
    Filed: October 2, 2009
    Publication date: April 1, 2010
    Applicant: RELIABLE BIOPHARMACEUTICAL, INC.
    Inventors: UmaShanker Sampath, Joseph A. Toce, Sourena Nadji
  • Process for the production of pentostatin aglycone and pentostatin
    Patent number: 7393954
    Abstract: A novel, scaleable and improved process for preparing pentostatin and its analogs is disclosed. The method comprises the diastereospecific synthesis of the nucleobase from commercially available L-Dialkyl tartarates.
    Type: Grant
    Filed: December 12, 2003
    Date of Patent: July 1, 2008
    Assignee: Reliable Biopharmaceutical Corporation
    Inventors: Sourena Nadji, James Smoot, UmaShanker Sampath
  • POLYMERIC NUCLEOSIDE PRODRUGS
    Publication number: 20070179112
    Abstract: Disclosed are polymeric compounds which are useful as prodrugs, comprising a chain of monomeric nucleosides, nucleoside analogs or abasic nucleosides, wherein at least one of the nucleosides or nucleoside analogs or a heterocyclic derivative thereof is pharmaceutically active and the nucleosides, nucleoside analogs or abasic nucleosides are linked by a phosphodiester group, a phosphorothioate group or an H—, alkyl or alkenyl phosphonate group.
    Type: Application
    Filed: January 29, 2007
    Publication date: August 2, 2007
    Applicant: Reliable Biopharmaceutical, Inc.
    Inventors: UmaShanker Sampath, Joseph Toce, Sourena Nadji
  • Process for the production of pentostatin aglycone and pentostatin
    Publication number: 20040181052
    Abstract: A novel, scaleable and improved process for preparing pentostatin and its analogs is disclosed. The method comprises the diastereospecific synthesis of the nucleobase from commercially available L-Dialkyl tartarates.
    Type: Application
    Filed: December 12, 2003
    Publication date: September 16, 2004
    Inventors: Nadji Sourena, James Smoot, UmaShanker Sampath
  • Polymeric nucleoside prodrugs
    Publication number: 20040132684
    Abstract: Disclosed are polymeric compounds which are useful as prodrugs, comprising a chain of monomeric nucleosides, nucleoside analogs or abasic nucleosides, wherein at least one of the nucleosides or nucleoside analogs or a heterocyclic derivative thereof is pharmaceutically active and the nucleosides, nucleoside analogs or abasic nucleosides are linked by a phosphodiester group, a phosphorothioate group or an H—, alkyl or alkenyl phosphonate group.
    Type: Application
    Filed: December 17, 2003
    Publication date: July 8, 2004
    Inventors: Umashanker Sampath, Joseph A. Toce, Sourena Nadji
  • Process for the production of 2-halo-6-aminopurine derivatives
    Patent number: 6596858
    Abstract: A novel process for preparing 2-halo-6-aminopurine derivatives and their analogs is disclosed. The method comprises halogenation of 2,6-diaminopurine derivatives at the C-2 position in a specific combination of aprotic polar and nonpolar organic solvents to give the corresponding halogenated derivatives.
    Type: Grant
    Filed: March 12, 2001
    Date of Patent: July 22, 2003
    Assignee: Reliable Biopharmaceutical, Inc.
    Inventors: UmaShanker Sampath, Lawrence Bartlett
  • Polymeric compounds useful as prodrugs
    Publication number: 20020013287
    Abstract: Disclosed are polymeric compounds which are useful as prodrugs, comprising a chain of monomeric nucleosides, nucleoside analogs or abasic nucleosides, wherein at least one of the nucleosides or nucleoside analogs or a heterocyclic derivative thereof is pharmaceutically active and the nucleosides, nucleoside analogs or abasic nucleosides are linked by a phosphodiester group, a phosphorothioate group or an H—, alkyl or alkenyl phosphonate group.
    Type: Application
    Filed: May 9, 2001
    Publication date: January 31, 2002
    Applicant: Reliable Biopharmaceuticals, Inc. St Louis Missouri
    Inventors: UmaShanker Sampath, Joseph A. Toce, Sourena Nadji
  • Process for the production of 2-halo-6-aminopurine derivatives
    Patent number: 6252061
    Abstract: A novel process for preparing 2-halo-6-aminopurine derivatives and their analogs is disclosed. The method comprises halogenation of 2,6-diaminopurine derivatives at the C-2 position in a specific combination of aprotic polar and nonpolar organic solvents to give the corresponding halogenated derivatives.
    Type: Grant
    Filed: March 23, 1999
    Date of Patent: June 26, 2001
    Assignee: Reliable Biopharmaceutical, Inc.
    Inventors: UmaShanker Sampath, Lawrence Bartlett