Patents by Inventor Umeharu Ohto

Umeharu Ohto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • S100A8-INHIBITING PEPTIDE AND DISEASE THERAPEUTIC AGENT CONTAINING SAME
    Publication number: 20230220005
    Abstract: S100A8-inhibiting peptides include (A) a peptide of 5 to 10 residues in length containing a fifth alanine (Ala) from an N-terminus in an amino acid sequence of SEQ ID NO: 1, or (B) a peptide consisting of an amino acid sequence of SEQ ID NO: 2.
    Type: Application
    Filed: May 26, 2021
    Publication date: July 13, 2023
    Applicants: TOKYO WOMEN'S MEDICAL UNIVERSITY, THE DOSHISHA
    Inventors: Yoshiro MARU, Atsuko DEGUCHI, Kiyotaka NISHIKAWA, Miho TAKAHASHI, Umeharu OHTO
  • ANTI-HUMAN TLR7 ANTIBODY
    Publication number: 20230212306
    Abstract: The present invention provides a pharmaceutical composition comprising an antibody which binds specifically to human TLR7 or monkey TLR7 and does not bind to mouse TLR7 or rat TLR7, and has an activity of inhibiting a function of human TLR7 or monkey TLR7, and the like.
    Type: Application
    Filed: December 27, 2022
    Publication date: July 6, 2023
    Applicants: Daiichi Sankyo Company, Limited, The University of Tokyo
    Inventors: Kensuke Miyake, Yusuke Murakami, Yuji Motoi, Atsuo Kanno, Toshiyuki Shimizu, Umeharu Ohto, Takaichi Shimozato, Atsushi Manno, Takashi Kagari, Jun Ishiguro, Kensuke Nakamura, Takashi Isobe
  • Anti-human TLR7 antibody
    Patent number: 11578138
    Abstract: The present invention provides a pharmaceutical composition comprising an antibody which binds specifically to human TLR7 or monkey TLR7 and does not bind to mouse TLR7 or rat TLR7, and has an activity of inhibiting a function of human TLR7 or monkey TLR7, and the like.
    Type: Grant
    Filed: July 2, 2021
    Date of Patent: February 14, 2023
    Assignees: Daiichi Sankyo Company, Limited, The University of Tokyo
    Inventors: Kensuke Miyake, Yusuke Murakami, Yuji Motoi, Atsuo Kanno, Toshiyuki Shimizu, Umeharu Ohto, Takaichi Shimozato, Atsushi Manno, Takashi Kagari, Jun Ishiguro, Kensuke Nakamura, Takashi Isobe
  • ANTI-HUMAN TLR7 ANTIBODY
    Publication number: 20210332149
    Abstract: The present invention provides a pharmaceutical composition comprising an antibody which binds specifically to human TLR7 or monkey TLR7 and does not bind to mouse TLR7 or rat TLR7, and has an activity of inhibiting a function of human TLR7 or monkey TLR7, and the like.
    Type: Application
    Filed: July 2, 2021
    Publication date: October 28, 2021
    Applicants: Daiichi Sankyo Company, Limited, The University of Tokyo
    Inventors: Kensuke Miyake, Yusuke Murakami, Yuji Motoi, Atsuo Kanno, Toshiyuki Shimizu, Umeharu Ohto, Takaichi Shimozato, Atsushi Manno, Takashi Kagari, Jun Ishiguro, Kensuke Nakamura, Takashi Isobe
  • Anti-human TLR7 antibody
    Patent number: 11091560
    Abstract: The present invention provides a pharmaceutical composition comprising an antibody which binds specifically to human TLR7 or monkey TLR7 and does not bind to mouse TLR7 or rat TLR7, and has an activity of inhibiting a function of human TLR7 or monkey TLR7, and the like.
    Type: Grant
    Filed: October 13, 2020
    Date of Patent: August 17, 2021
    Assignees: Daiichi Sankyo Company, Limited, The University of Tokyo
    Inventors: Kensuke Miyake, Yusuke Murakami, Yuji Motoi, Atsuo Kanno, Toshiyuki Shimizu, Umeharu Ohto, Takaichi Shimozato, Atsushi Manno, Takashi Kagari, Jun Ishiguro, Kensuke Nakamura, Takashi Isobe
  • ANALYSIS OF SOLUBLE TLR7 IN HUMAN-DERIVED SAMPLE
    Publication number: 20210199667
    Abstract: An object of the present invention is to provide a technique for detecting human TLR7. Human TLR7 in a sample can be detected through an ELISA method or the like using an anti-human TLR7 antibody. The present invention enables use of human TLR7 as a marker indicating the pathological condition of an autoimmune disease.
    Type: Application
    Filed: May 30, 2019
    Publication date: July 1, 2021
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Kensuke MIYAKE, Yusuke MURAKAMI, Yuji MOTOI, Toshiyuki SHIMIZU, Umeharu OHTO
  • ANTI-HUMAN TLR7 ANTIBODY
    Publication number: 20210040225
    Abstract: The present invention provides a pharmaceutical composition comprising an antibody which binds specifically to human TLR7 or monkey TLR7 and does not bind to mouse TLR7 or rat TLR7, and has an activity of inhibiting a function of human TLR7 or monkey TLR7, and the like.
    Type: Application
    Filed: October 13, 2020
    Publication date: February 11, 2021
    Applicants: Daiichi Sankyo Company, Limited, The University of Tokyo
    Inventors: Kensuke Miyake, Yusuke Murakami, Yuji Motoi, Atsuo Kanno, Toshiyuki Shimizu, Umeharu Ohto, Takaichi Shimozato, Atsushi Manno, Takashi Kagari, Jun Ishiguro, Kensuke Nakamura, Takashi Isobe