Patents by Inventor Umesh Ahuja

Umesh Ahuja has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of using presenting N-glycan or derivatives thereof
    Patent number: 9764021
    Abstract: The present invention relates to Salmonella enterica comprising at least pgl operon of Campylobacter jejuni or a functional derivative thereof and presenting at least one N-glycan of Campylobacter jejuni or N-glycan derivative thereof on its cell surface and, in particular, to medical uses and pharmaceutical compositions thereof as well as methods for treating and/or preventing Campylobacter and optionally Salmonella infections and methods for producing these Salmonella strains.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: September 19, 2017
    Assignee: EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZURICH
    Inventors: Karin Ilg, Markus Aebi, Umesh Ahuja, Saba Amber, Flavio Schwartz
  • Recombinant N-glycosylated proteins from procaryotic cells
    Patent number: 9551019
    Abstract: The present invention relates to recombinant N-glycosylated proteins, comprising one or more introduced N-glycosylated optimized amino acid sequence(s), nucleic acids encoding these proteins as well as corresponding vectors and host cells. In addition, the present invention is directed to the use of said proteins, nucleic acids, vectors and host cells for preparing medicaments. Furthermore, the present invention provides methods for producing said proteins.
    Type: Grant
    Filed: February 6, 2014
    Date of Patent: January 24, 2017
    Assignee: ETH ZÜRICH
    Inventors: Markus Aebi, Michael Kowarik, Umesh Ahuja
  • RECOMBINANT N-GLYCOSYLATED PROTEINS FROM PROCARYOTIC CELLS
    Publication number: 20160326563
    Abstract: The present invention relates to recombinant N-glycosylated proteins, comprising one or more introduced N-glycosylated optimized amino acid sequence(s), nucleic acids encoding these proteins as well as corresponding vectors and host cells. In addition, the present invention is directed to the use of said proteins, nucleic acids, vectors and host cells for preparing medicaments. Furthermore, the present invention provides methods for producing said proteins.
    Type: Application
    Filed: May 19, 2016
    Publication date: November 10, 2016
    Applicant: ETH ZÜRICH
    Inventors: Markus Aebi, Michael Kowarik, Umesh Ahuja
  • Methods of using Salmonella enterica presenting C. Jejuni N-glycan or derivatives thereof
    Publication number: 20160213770
    Abstract: The present invention relates to Salmonella enterica comprising at least pgl operon of Campylobacter jejuni or a functional derivative thereof and presenting at least one N-glycan of Campylobacter jejuni or N-glycan derivative thereof on its cell surface and, in particular, to medical uses and pharmaceutical compositions thereof as well as methods for treating and/or preventing Campylobacter and optionally Salmonella infections and methods for producing these Salmonella strains.
    Type: Application
    Filed: April 8, 2016
    Publication date: July 28, 2016
    Inventors: Karin Ilg, Markus Aebi, Umesh Ahuja, Saba Amber, Flavio Schwartz
  • presenting N-glycan or derivatives thereof
    Patent number: 9309493
    Abstract: The present invention relates to Salmonella enterica comprising at least one pgl operon of Campylobacter jejuni or a functional derivative thereof and presenting at least one N-glycan of Campylobacter jejuni or N-glycan derivative thereof on its cell surface. In addition, it is directed to medical uses and pharmaceutical compositions thereof as well as methods for treating and/or preventing Campylobacter and optionally Salmonella infections and methods for producing these Salmonella strains.
    Type: Grant
    Filed: March 25, 2010
    Date of Patent: April 12, 2016
    Assignee: Eidgenoessische Technische Hochschule Zurich
    Inventors: Karin Ilg, Markus Aebi, Umesh Ahuja, Saba Amber, Flavio Schwarz
  • RECOMBINANT N-GLYCOSYLATED PROTEINS FROM PROCARYOTIC CELLS
    Publication number: 20140323700
    Abstract: The present invention relates to recombinant N-glycosylated proteins, comprising one or more introduced N-glycosylated optimized amino acid sequence(s), nucleic acids encoding these proteins as well as corresponding vectors and host cells. In addition, the present invention is directed to the use of said proteins, nucleic acids, vectors and host cells for preparing medicaments. Furthermore, the present invention provides methods for producing said proteins.
    Type: Application
    Filed: February 6, 2014
    Publication date: October 30, 2014
    Applicant: ETH ZÜRICH
    Inventors: Markus Aebi, Michael Kowarik, Umesh Ahuja
  • Recombinant N-glycosylated proteins from procaryotic cells
    Patent number: 8753864
    Abstract: The present invention relates to recombinant N-glycosylated proteins, comprising one or more introduced N-glycosylated optimized amino acid sequence(s), nucleic acids encoding these proteins as well as corresponding vectors and host cells. In addition, the present invention is directed to the use of said proteins, nucleic acids, vectors and host cells for preparing medicaments. Furthermore, the present invention provides methods for producing said proteins.
    Type: Grant
    Filed: May 10, 2006
    Date of Patent: June 17, 2014
    Assignee: ETH Zurich
    Inventors: Markus Aebi, Michael Kowarik, Umesh Ahuja
  • SALMONELLA ENTERICA PRESENTING C. JEJUNI N-GLYCAN OR DERIVATIVES THEREOF
    Publication number: 20120100177
    Abstract: The present invention relates to Salmonella enterica comprising at least one pgl operon of Campylobacter jejuni or a functional derivative thereof and presenting at least one N-glycan of Campylobacter jejuni or N-glycan derivative thereof on its cell surface. In addition, it is directed to medical uses and pharmaceutical compositions thereof as well as methods for treating and/or preventing Campylobacter and optionally Salmonella infections and methods for producing these Salmonella strains.
    Type: Application
    Filed: March 25, 2010
    Publication date: April 26, 2012
    Inventors: Karin Ilg, Markus Aebi, Umesh Ahuja, Saba Amber, Flavio Schwarz
  • Recombinant n-glycosylated proteins from procaryotic cells
    Publication number: 20100062484
    Abstract: The present invention relates to recombinant N-glycosylated proteins, comprising one or more introduced N-glycosylated optimized amino acid sequence(s), nucleic acids encoding these proteins as well as corresponding vectors and host cells. In addition, the present invention is directed to the use of said proteins, nucleic acids, vectors and host cells for preparing medicaments. Furthermore, the present invention provides methods for producing said proteins.
    Type: Application
    Filed: May 10, 2006
    Publication date: March 11, 2010
    Applicant: Eidgenossische Technische Hochschule Zurich
    Inventors: Markus Aebi, Machael Kowarik, Umesh Ahuja