Patents by Inventor Umesh H. Patel
Umesh H. Patel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12048302Abstract: Disclosed are products having animal tissue packed within the lumen of a device such as a needle cannula and being therein impregnated with a cryopreservation medium. The needle cannula or other device can be received in a capsule and/or other container, which in some forms can contain additional amounts of the cryopreservation medium occurring external of the lumen. Methods of use of the products are also described and can include ejecting the animal tissue from the lumen of device using pressurized liquid passed through the lumen, potentially to deliver the animal tissue directly into a patient. Methods of manufacture of the products are also described.Type: GrantFiled: March 3, 2020Date of Patent: July 30, 2024Assignee: Cook Biotech IncorporatedInventors: Umesh H. Patel, Michael L. Taylor, Claus Soendergaard, Cara McCammon, Rae Ritchie
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Patent number: 11696749Abstract: Described are medical graft products, systems, and methods for treating fistulae. Certain products of the invention are configured to have portions residing in and around a primary fistula opening, e.g., one occurring in a wall of the alimentary canal. One such product includes a biocompatible graft body which is configured to block at least the primary opening. The graft body includes a capping member, which is configured to contact portions of the alimentary canal wall adjacent to the primary opening, and an elongate plug member extending from the capping member, which is configured to extend into at least a portion of the fistula. In certain embodiments, a graft body component has the capacity to expand or otherwise change form to provide a suitable capping arrangement. Such a component can include a resilient wire frame, e.g., one that is self-expandable or one that requires at least some manipulation in order to expand.Type: GrantFiled: December 8, 2016Date of Patent: July 11, 2023Assignee: Cook Biotech IncorporatedInventors: Umesh H. Patel, F. Joseph Obermiller
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Patent number: 11583276Abstract: Described are medical devices useful for applying a bolster material to a surgical fastening device such as a stapler, and related methods of manufacture and use. The devices include an applicator element for receipt between arms of the stapler, and a bolster material, desirably a remodelable extracellular matrix material, coupled to the applicator element. In certain embodiments, the bolster material is held by the applicator element, for example having at least a portion looped around or received through or over a portion of the applicator element. Also described are unique implantable materials including coatings of dried, reversible adhesive.Type: GrantFiled: December 18, 2019Date of Patent: February 21, 2023Assignee: Cook Biotech IncorporatedInventors: Michael C. Hiles, Umesh H. Patel, Bhavin Shah, Chad S. McAlexander
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Publication number: 20220296351Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft with an illustrative graft comprising a remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.Type: ApplicationFiled: June 6, 2022Publication date: September 22, 2022Applicant: Cook Biotech IncorporatedInventors: Umesh H. Patel, Jeffrey Miller, Neal E. Fearnot, Mark W. Bleyer
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Patent number: 11351021Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft with an illustrative graft comprising a remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.Type: GrantFiled: March 29, 2016Date of Patent: June 7, 2022Assignee: Cook Biotech IncorporatedInventors: Umesh H. Patel, Jeffrey Miller, Neal E. Fearnot, Mark W. Bleyer
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Publication number: 20210386912Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft comprising remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.Type: ApplicationFiled: August 30, 2021Publication date: December 16, 2021Applicant: Cook Biotech IncorporatedInventors: Umesh H. Patel, Jeffrey Miller
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Publication number: 20210308342Abstract: The present invention provides, in certain aspects, medical graft products that incorporate multiple drug depots in and/or on the products. One such product is a sheet graft construct, for example for tissue support that includes a sheet graft material with a plurality of drug depots. The drug depots can be hardened deposits formed directly onto the sheet graft material and/or can be capable of eluting a drug for a minimum of 72 hours.Type: ApplicationFiled: June 22, 2021Publication date: October 7, 2021Applicants: Cook Medical Technologies LLC, Cook Biotech IncorporatedInventors: Rhonda Peck, Bhavin B. Shah, Umesh H. Patel, Krista Gearhart, Steven Charlebois, Keith Milner, Eric J. Rodenberg
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Patent number: 11065368Abstract: The present invention provides, in certain aspects, medical graft products that incorporate multiple drug depots in and/or on the products. One such product is a sheet graft construct, for example for tissue support that includes a sheet graft material with a plurality of drug depots. The drug depots can be hardened deposits formed directly onto the sheet graft material and/or can be capable of eluting a drug for a minimum of 72 hours.Type: GrantFiled: March 14, 2014Date of Patent: July 20, 2021Assignees: Cook Biotech Incorporated, Cook Medical Technologies LLCInventors: Rhonda Peck, Bhavin Shah, Umesh H. Patel, Krista Gearhart, Steven Charlebois, Keith Milner, Eric J. Rodenberg
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Publication number: 20200405976Abstract: Disclosed are products having animal tissue packed within the lumen of a device such as a needle cannula. The needle cannula or other device can be received in a capsule and/or other container. Methods of use of the products are also described and can include ejecting the animal tissue from the lumen of device using pressurized liquid passed through the lumen, potentially to deliver the animal tissue directly into a patient. Methods of manufacture of the products are also described.Type: ApplicationFiled: May 13, 2020Publication date: December 31, 2020Applicant: Cook Biotech IncorporatedInventors: Umesh H. Patel, Michael L. Taylor, Cara McCammon, Rae Ritchie
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Publication number: 20200375177Abstract: Disclosed are products having animal tissue packed within the lumen of a device such as a needle cannula and being therein impregnated with a cryopreservation medium. The needle cannula or other device can be received in a capsule and/or other container, which in some forms can contain additional amounts of the cryopreservation medium occurring external of the lumen. Methods of use of the products are also described and can include ejecting the animal tissue from the lumen of device using pressurized liquid passed through the lumen, potentially to deliver the animal tissue directly into a patient. Methods of manufacture of the products are also described.Type: ApplicationFiled: March 3, 2020Publication date: December 3, 2020Applicant: Cook Biotech IncorporatedInventors: Umesh H. Patel, Michael L. Taylor, Claus Soendergaard, Cara McCammon, Rae Ritchie
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Publication number: 20200316257Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft comprising remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.Type: ApplicationFiled: June 19, 2020Publication date: October 8, 2020Applicant: Cook Biotech IncorporatedInventors: Umesh H. Patel, Jeffrey Miller
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Patent number: 10688219Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft comprising remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.Type: GrantFiled: June 10, 2009Date of Patent: June 23, 2020Assignee: Cook Biotech IncorporatedInventors: Umesh H. Patel, Jeffrey Miller
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Publication number: 20200121318Abstract: Described are medical devices useful for applying a bolster material to a surgical fastening device such as a stapler, and related methods of manufacture and use. The devices include an applicator element for receipt between arms of the stapler, and a bolster material, desirably a remodelable extracellular matrix material, coupled to the applicator element. In certain embodiments, the bolster material is held by the applicator element, for example having at least a portion looped around or received through or over a portion of the applicator element. Also described are unique implantable materials including coatings of dried, reversible adhesive.Type: ApplicationFiled: December 18, 2019Publication date: April 23, 2020Inventors: Michael C. Hiles, Umesh H. Patel, Bhavin Shah, Chad S. McAlexander
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Patent number: 10575516Abstract: Disclosed are products having animal tissue packed within the lumen of a device such as a needle cannula and being therein impregnated with a cryopreservation medium. The needle cannula or other device can be received in a capsule and/or other container, which in some forms can contain additional amounts of the cryopreservation medium occurring external of the lumen. Methods of use of the products are also described and can include ejecting the animal tissue from the lumen of device using pressurized liquid passed through the lumen, potentially to deliver the animal tissue directly into a patient. Methods of manufacture of the products are also described.Type: GrantFiled: November 14, 2018Date of Patent: March 3, 2020Assignee: Cook Biotech IncorporatedInventors: Umesh H. Patel, Michael L. Taylor, Claus Sondergaard, Cara McCammon, Rae Ritchie
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Patent number: 10512463Abstract: Described are medical devices useful for applying a bolster material to a surgical fastening device such as a stapler, and related methods of manufacture and use. The devices include an applicator element for receipt between arms of the stapler, and a bolster material, desirably a remodelable extracellular matrix material, coupled to the applicator element. In certain embodiments, the bolster material is held by the applicator element, for example having at least a portion looped around or received through or over a portion of the applicator element. Also described are unique implantable materials including coatings of dried, reversible adhesive.Type: GrantFiled: October 2, 2015Date of Patent: December 24, 2019Assignee: Cook Biotech IncorporatedInventors: Michael C. Hiles, Umesh H. Patel, Bhavin Shah, Chad S. McAlexander
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Publication number: 20190141987Abstract: Disclosed are products having animal tissue packed within the lumen of a device such as a needle cannula and being therein impregnated with a cryopreservation medium. The needle cannula or other device can be received in a capsule and/or other container, which in some forms can contain additional amounts of the cryopreservation medium occurring external of the lumen. Methods of use of the products are also described and can include ejecting the animal tissue from the lumen of device using pressurized liquid passed through the lumen, potentially to deliver the animal tissue directly into a patient. Methods of manufacture of the products are also described.Type: ApplicationFiled: November 14, 2018Publication date: May 16, 2019Applicant: Cook Biotech IncorporatedInventors: Umesh H. Patel, Michael L. Taylor, Claus Sondergaard, Cara McCammon, Rae Ritchie
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Patent number: 10226256Abstract: This invention relates in one aspect to the treatment of a vascular vessel with a biomaterial. The biomaterial can be a remodelable material that strengthens and/or supports the vessel walls. Additionally the biomaterial can include a variety of naturally occurring or added bioactive agents and/or viable cellular populations.Type: GrantFiled: February 4, 2014Date of Patent: March 12, 2019Assignees: Cook Medical Technologies LLC, Cook Biotech IncorporatedInventors: Brian C. Case, Jacob A. Flagle, Michael C. Hiles, Umesh H. Patel, F. Joseph Obermiller
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Patent number: 9956315Abstract: Described are medical products, systems, and methods for treating fistulae having a primary opening, such as in the alimentary canal. Certain methods of the invention include providing an implantable material including a compliant sheet form biocompatible material, and forcing this sheet form biocompatible material into the primary opening so as to deform the sheet form biocompatible material to conform to and block the primary opening. The biocompatible material preferably comprises a remodelable material, for example, a remodelable extracellular matrix material such as submucosa.Type: GrantFiled: April 28, 2006Date of Patent: May 1, 2018Assignee: Cook Biotech IncorporatedInventors: Umesh H. Patel, F. Joseph Obermiller, Matthew R. Graham
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Patent number: 9827271Abstract: Lung volume reduction by isolating a target lung portion from the rest of the lung with a mass of extracellular matrix (“ECM”) material. The procedure can be performed by locating a tube within the lumen of an airway to be obstructed and depositing an amount of flowable or other ECM in the open space until the lumen is occluded. Optionally, the procedure may be performed by delivering a plug substantially comprised of ECM material into the lumen of an airway to be obstructed. Further optionally, the ECM plug may include a one-way valve to allow air and mucous to escape from the isolated lung portion.Type: GrantFiled: March 14, 2014Date of Patent: November 28, 2017Assignee: Cook Biotech IncorporatedInventors: Umesh H. Patel, Bhavin Shah, Michelle Chutka
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Publication number: 20170086808Abstract: Described are medical graft products, systems, and methods for treating fistulae. Certain products of the invention are configured to have portions residing in and around a primary fistula opening, e.g., one occurring in a wall of the alimentary canal. One such product includes a biocompatible graft body which is configured to block at least the primary opening. The graft body includes a capping member, which is configured to contact portions of the alimentary canal wall adjacent to the primary opening, and an elongate plug member extending from the capping member, which is configured to extend into at least a portion of the fistula. In certain embodiments, a graft body component has the capacity to expand or otherwise change form to provide a suitable capping arrangement. Such a component can include a resilient wire frame, e.g., one that is self-expandable or one that requires at least some manipulation in order to expand.Type: ApplicationFiled: December 8, 2016Publication date: March 30, 2017Inventors: Umesh H. Patel, F. Joseph Obermiller