Patents by Inventor Umesh H. Patel

Umesh H. Patel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210308342
    Abstract: The present invention provides, in certain aspects, medical graft products that incorporate multiple drug depots in and/or on the products. One such product is a sheet graft construct, for example for tissue support that includes a sheet graft material with a plurality of drug depots. The drug depots can be hardened deposits formed directly onto the sheet graft material and/or can be capable of eluting a drug for a minimum of 72 hours.
    Type: Application
    Filed: June 22, 2021
    Publication date: October 7, 2021
    Applicants: Cook Medical Technologies LLC, Cook Biotech Incorporated
    Inventors: Rhonda Peck, Bhavin B. Shah, Umesh H. Patel, Krista Gearhart, Steven Charlebois, Keith Milner, Eric J. Rodenberg
  • Patent number: 11065368
    Abstract: The present invention provides, in certain aspects, medical graft products that incorporate multiple drug depots in and/or on the products. One such product is a sheet graft construct, for example for tissue support that includes a sheet graft material with a plurality of drug depots. The drug depots can be hardened deposits formed directly onto the sheet graft material and/or can be capable of eluting a drug for a minimum of 72 hours.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: July 20, 2021
    Assignees: Cook Biotech Incorporated, Cook Medical Technologies LLC
    Inventors: Rhonda Peck, Bhavin Shah, Umesh H. Patel, Krista Gearhart, Steven Charlebois, Keith Milner, Eric J. Rodenberg
  • Publication number: 20200405976
    Abstract: Disclosed are products having animal tissue packed within the lumen of a device such as a needle cannula. The needle cannula or other device can be received in a capsule and/or other container. Methods of use of the products are also described and can include ejecting the animal tissue from the lumen of device using pressurized liquid passed through the lumen, potentially to deliver the animal tissue directly into a patient. Methods of manufacture of the products are also described.
    Type: Application
    Filed: May 13, 2020
    Publication date: December 31, 2020
    Applicant: Cook Biotech Incorporated
    Inventors: Umesh H. Patel, Michael L. Taylor, Cara McCammon, Rae Ritchie
  • Publication number: 20200375177
    Abstract: Disclosed are products having animal tissue packed within the lumen of a device such as a needle cannula and being therein impregnated with a cryopreservation medium. The needle cannula or other device can be received in a capsule and/or other container, which in some forms can contain additional amounts of the cryopreservation medium occurring external of the lumen. Methods of use of the products are also described and can include ejecting the animal tissue from the lumen of device using pressurized liquid passed through the lumen, potentially to deliver the animal tissue directly into a patient. Methods of manufacture of the products are also described.
    Type: Application
    Filed: March 3, 2020
    Publication date: December 3, 2020
    Applicant: Cook Biotech Incorporated
    Inventors: Umesh H. Patel, Michael L. Taylor, Claus Soendergaard, Cara McCammon, Rae Ritchie
  • Publication number: 20200316257
    Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft comprising remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.
    Type: Application
    Filed: June 19, 2020
    Publication date: October 8, 2020
    Applicant: Cook Biotech Incorporated
    Inventors: Umesh H. Patel, Jeffrey Miller
  • Patent number: 10688219
    Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft comprising remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.
    Type: Grant
    Filed: June 10, 2009
    Date of Patent: June 23, 2020
    Assignee: Cook Biotech Incorporated
    Inventors: Umesh H. Patel, Jeffrey Miller
  • Publication number: 20200121318
    Abstract: Described are medical devices useful for applying a bolster material to a surgical fastening device such as a stapler, and related methods of manufacture and use. The devices include an applicator element for receipt between arms of the stapler, and a bolster material, desirably a remodelable extracellular matrix material, coupled to the applicator element. In certain embodiments, the bolster material is held by the applicator element, for example having at least a portion looped around or received through or over a portion of the applicator element. Also described are unique implantable materials including coatings of dried, reversible adhesive.
    Type: Application
    Filed: December 18, 2019
    Publication date: April 23, 2020
    Inventors: Michael C. Hiles, Umesh H. Patel, Bhavin Shah, Chad S. McAlexander
  • Patent number: 10575516
    Abstract: Disclosed are products having animal tissue packed within the lumen of a device such as a needle cannula and being therein impregnated with a cryopreservation medium. The needle cannula or other device can be received in a capsule and/or other container, which in some forms can contain additional amounts of the cryopreservation medium occurring external of the lumen. Methods of use of the products are also described and can include ejecting the animal tissue from the lumen of device using pressurized liquid passed through the lumen, potentially to deliver the animal tissue directly into a patient. Methods of manufacture of the products are also described.
    Type: Grant
    Filed: November 14, 2018
    Date of Patent: March 3, 2020
    Assignee: Cook Biotech Incorporated
    Inventors: Umesh H. Patel, Michael L. Taylor, Claus Sondergaard, Cara McCammon, Rae Ritchie
  • Patent number: 10512463
    Abstract: Described are medical devices useful for applying a bolster material to a surgical fastening device such as a stapler, and related methods of manufacture and use. The devices include an applicator element for receipt between arms of the stapler, and a bolster material, desirably a remodelable extracellular matrix material, coupled to the applicator element. In certain embodiments, the bolster material is held by the applicator element, for example having at least a portion looped around or received through or over a portion of the applicator element. Also described are unique implantable materials including coatings of dried, reversible adhesive.
    Type: Grant
    Filed: October 2, 2015
    Date of Patent: December 24, 2019
    Assignee: Cook Biotech Incorporated
    Inventors: Michael C. Hiles, Umesh H. Patel, Bhavin Shah, Chad S. McAlexander
  • Publication number: 20190141987
    Abstract: Disclosed are products having animal tissue packed within the lumen of a device such as a needle cannula and being therein impregnated with a cryopreservation medium. The needle cannula or other device can be received in a capsule and/or other container, which in some forms can contain additional amounts of the cryopreservation medium occurring external of the lumen. Methods of use of the products are also described and can include ejecting the animal tissue from the lumen of device using pressurized liquid passed through the lumen, potentially to deliver the animal tissue directly into a patient. Methods of manufacture of the products are also described.
    Type: Application
    Filed: November 14, 2018
    Publication date: May 16, 2019
    Applicant: Cook Biotech Incorporated
    Inventors: Umesh H. Patel, Michael L. Taylor, Claus Sondergaard, Cara McCammon, Rae Ritchie
  • Patent number: 10226256
    Abstract: This invention relates in one aspect to the treatment of a vascular vessel with a biomaterial. The biomaterial can be a remodelable material that strengthens and/or supports the vessel walls. Additionally the biomaterial can include a variety of naturally occurring or added bioactive agents and/or viable cellular populations.
    Type: Grant
    Filed: February 4, 2014
    Date of Patent: March 12, 2019
    Assignees: Cook Medical Technologies LLC, Cook Biotech Incorporated
    Inventors: Brian C. Case, Jacob A. Flagle, Michael C. Hiles, Umesh H. Patel, F. Joseph Obermiller
  • Patent number: 9956315
    Abstract: Described are medical products, systems, and methods for treating fistulae having a primary opening, such as in the alimentary canal. Certain methods of the invention include providing an implantable material including a compliant sheet form biocompatible material, and forcing this sheet form biocompatible material into the primary opening so as to deform the sheet form biocompatible material to conform to and block the primary opening. The biocompatible material preferably comprises a remodelable material, for example, a remodelable extracellular matrix material such as submucosa.
    Type: Grant
    Filed: April 28, 2006
    Date of Patent: May 1, 2018
    Assignee: Cook Biotech Incorporated
    Inventors: Umesh H. Patel, F. Joseph Obermiller, Matthew R. Graham
  • Patent number: 9827271
    Abstract: Lung volume reduction by isolating a target lung portion from the rest of the lung with a mass of extracellular matrix (“ECM”) material. The procedure can be performed by locating a tube within the lumen of an airway to be obstructed and depositing an amount of flowable or other ECM in the open space until the lumen is occluded. Optionally, the procedure may be performed by delivering a plug substantially comprised of ECM material into the lumen of an airway to be obstructed. Further optionally, the ECM plug may include a one-way valve to allow air and mucous to escape from the isolated lung portion.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: November 28, 2017
    Assignee: Cook Biotech Incorporated
    Inventors: Umesh H. Patel, Bhavin Shah, Michelle Chutka
  • Publication number: 20170086808
    Abstract: Described are medical graft products, systems, and methods for treating fistulae. Certain products of the invention are configured to have portions residing in and around a primary fistula opening, e.g., one occurring in a wall of the alimentary canal. One such product includes a biocompatible graft body which is configured to block at least the primary opening. The graft body includes a capping member, which is configured to contact portions of the alimentary canal wall adjacent to the primary opening, and an elongate plug member extending from the capping member, which is configured to extend into at least a portion of the fistula. In certain embodiments, a graft body component has the capacity to expand or otherwise change form to provide a suitable capping arrangement. Such a component can include a resilient wire frame, e.g., one that is self-expandable or one that requires at least some manipulation in order to expand.
    Type: Application
    Filed: December 8, 2016
    Publication date: March 30, 2017
    Inventors: Umesh H. Patel, F. Joseph Obermiller
  • Patent number: 9538996
    Abstract: Described are medical graft products, systems, and methods for treating fistulae. Certain products of the invention are configured to have portions residing in and around a primary fistula opening, e.g., one occurring in a wall of the alimentary canal. One such product includes a biocompatible graft body which is configured to block at least the primary opening. The graft body includes a capping member, which is configured to contact portions of the alimentary canal wall adjacent to the primary opening, and an elongate plug member extending from the capping member, which is configured to extend into at least a portion of the fistula. In certain embodiments, a graft body component has the capacity to expand or otherwise change form to provide a suitable capping arrangement. Such a component can include a resilient wire frame, e.g., one that is self-expandable or one that requires at least some manipulation in order to expand.
    Type: Grant
    Filed: January 31, 2007
    Date of Patent: January 10, 2017
    Assignee: Cook Biotech Incorporated
    Inventors: Umesh H. Patel, F. Joseph Obermiller
  • Patent number: 9456815
    Abstract: An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.
    Type: Grant
    Filed: August 21, 2014
    Date of Patent: October 4, 2016
    Assignees: COOK MEDICAL TECHNOLOGIES LLC, COOK BIOTECH INCORPORATED
    Inventors: David N. Armstrong, Brian L. Bates, Mark W. Bleyer, F. Joseph Obermiller, Umesh H. Patel
  • Publication number: 20160220250
    Abstract: Described are medical devices useful for applying a bolster material to a surgical fastening device such as a stapler, and related methods of manufacture and use. The devices include an applicator element for receipt between arms of the stapler, and a bolster material, desirably a remodelable extracellular matrix material, coupled to the applicator element. In certain embodiments, the bolster material is held by the applicator element, for example having at least a portion looped around or received through or over a portion of the applicator element. Also described are unique implantable materials including coatings of dried, reversible adhesive.
    Type: Application
    Filed: October 2, 2015
    Publication date: August 4, 2016
    Inventors: Michael C. Hiles, Umesh H. Patel, Bhavin Shah, Chad S. McAlexander
  • Publication number: 20160206785
    Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft with an illustrative graft comprising a remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.
    Type: Application
    Filed: March 29, 2016
    Publication date: July 21, 2016
    Inventors: Umesh H. Patel, Jeffrey Miller, Neal E. Fearnot, Mark W. Bleyer
  • Patent number: 9295757
    Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft with an illustrative graft comprising a remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.
    Type: Grant
    Filed: December 10, 2010
    Date of Patent: March 29, 2016
    Assignee: Cook Biotech Incorporated
    Inventors: Umesh H. Patel, Jeffrey Miller, Neal E. Fearnot, Mark W. Bleyer
  • Patent number: 9271817
    Abstract: Tissue augmentation devices, as well as methods of manufacturing and using the same, are disclosed. In certain embodiments, a tissue augmentation device comprises an elongate tissue penetrating member and an amount of remodelable material, wherein at least a portion of the elongate member is cannulated, and at least a portion of the amount of material is received within at least a portion of the cannulated portion of the elongate member. The elongate tissue penetrating member may provide at least one deformation that is configured to constrict portions of the amount of remodelable material received within the elongate member. In alternate embodiments, a flexible covering over an implantable biomaterial provides protection and allows an easier delivery of the biomaterial to a tissue tract.
    Type: Grant
    Filed: May 2, 2008
    Date of Patent: March 1, 2016
    Assignee: Cook Biotech Incorporated
    Inventors: Ryan Dempsey, Jeffrey Miller, Steve Chen, Umesh H. Patel, F. Joseph Obermiller, Bhavin Shah, Chad E. Johnson