Patents by Inventor Umesh K. Jinwal

Umesh K. Jinwal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating TDP-43 proteinopathies using hexachlorophene
    Patent number: 9844519
    Abstract: A method of treating TDP-43 proteinopathies such as Alzheimer's disease, amyotrophic lateral sclerosis, and fronto-temporal lobar dementia is presented herein. It was found that administering hexachlorophene to cells expressing endogenous TDP-43 or overexpressing wild-type TDP-43 reduced accumulation of TDP-43 in the cells.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: December 19, 2017
    Assignee: University of South Florida
    Inventors: Umesh K. Jinwal, Diego A. Peralta, Malathi Narayan
  • Method of treating diseases associated with LRRK2 mutation using hexachlorophene
    Patent number: 9750753
    Abstract: A method of treating a disease associated with mutation of LRRK2 protein is presented herein. It was found that administering hexachlorophene to cells expressing endogenous LRRK2 or overexpressing wild-type or mutant LRRK2 reduced the total LRRK2 level in the cells.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: September 5, 2017
    Assignee: University of South Florida
    Inventors: Umesh K. Jinwal, Malathi Narayan