Patents by Inventor Umesh Muchhal

Umesh Muchhal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DNA shuffling to produce herbicide selective crops
    Publication number: 20060253922
    Abstract: Methods of shuffling DNA to obtain recombinant herbicide tolerance nucleic acids encoding proteins having new or improved herbicide tolerance activities, libraries of shuffled herbicide tolerance nucleic acids, transgenic plants and DNA shuffling mixtures are provided.
    Type: Application
    Filed: May 17, 2006
    Publication date: November 9, 2006
    Inventors: Venkiteswaran Subramanian, Willem Stemmer, Linda Castle, Umesh Muchhal, Daniel Siehl
  • DNA shuffling to produce herbicide selective crops
    Publication number: 20060242731
    Abstract: Methods of shuffling DNA to obtain recombinant herbicide tolerance nucleic acids encoding proteins having new or improved herbicide tolerance activities, libraries of shuffled herbicide tolerance nucleic acids, transgenic plants and DNA shuffling mixtures are provided.
    Type: Application
    Filed: May 17, 2006
    Publication date: October 26, 2006
    Inventors: Venkiteswaran Subramanian, Willem Stemmer, Linda Castle, Umesh Muchhal, Daniel Siehl
  • Analysis of MHC-peptide binding interactions
    Publication number: 20060228758
    Abstract: Methods, apparatuses, and compounds for screening or detecting binding of candidate peptides to an MHC protein is provided. A first component including at least one candidate peptides and a second component including at least one MHC protein are contacted. One of the components is immobilized on a solid support. The presence, absence, or quantity of binding of the peptide and said MHC protein is then determined.
    Type: Application
    Filed: March 23, 2006
    Publication date: October 12, 2006
    Inventors: Umesh Muchhal, John Desjarlais, Gregory Moore
  • Analysis of MHC-peptide binding interactions
    Publication number: 20060228759
    Abstract: Methods, apparatuses, and compounds for screening or detecting binding of candidate peptides to an MHC protein is provided. A first component including at least one candidate peptides and a second component including at least one MHC protein are contacted. One of the components is immobilized on a solid support. The presence, absence, or quantity of binding of the peptide and said MHC protein is then determined.
    Type: Application
    Filed: March 23, 2006
    Publication date: October 12, 2006
    Inventors: Umesh Muchhal, John Desjarlais, Gregory Moore
  • Nucleic acids and proteins with thioredoxin reductase activity
    Publication number: 20060149482
    Abstract: The present invention relates to the use of a variety of methods for generating functional thioredoxin reductase variants in which at least one physical, chemical or biological property of the variant is altered in a specific and desired manner when compared to the wild-type protein.
    Type: Application
    Filed: December 22, 2005
    Publication date: July 6, 2006
    Inventors: Bipin Dalmia, Steven Briggs, Greg del Val, John Desjarlais, Peter Heifetz, Peter Luginbuhl, Umesh Muchhal
  • Nucleic acids and proteins with thioredoxin reductase activity
    Patent number: 7071307
    Abstract: The present invention relates to the use of a variety of methods for generating functional thioredoxin reductase variants in which at least one physical, chemical or biological property of the variant is altered in a specific and desired manner when compared to the wild-type protein.
    Type: Grant
    Filed: May 6, 2002
    Date of Patent: July 4, 2006
    Assignees: Syngenta Participations AG, Xencor, Inc.
    Inventors: Bipin K. Dalmia, Steven P. Briggs, Greg del Val, John R. Desjarlais, Peter Heifetz, Peter Luginbuhl, Umesh Muchhal
  • Analysis of MHC-peptide binding interactions
    Publication number: 20060084116
    Abstract: Methods, apparatuses, and compounds for screening or detecting binding of candidate peptides to an MHC construct is provided. A first component including at least one candidate peptides and a second component including at least one MHC construct are contacted. One of the components is immobilized on a solid support. The presence, absence, or quantity of binding of the peptide and said MHC construct is then determined.
    Type: Application
    Filed: September 13, 2005
    Publication date: April 20, 2006
    Applicant: Xencor, Inc.
    Inventor: Umesh Muchhal
  • DNA shuffling to produce herbicide selective crops
    Publication number: 20050060767
    Abstract: Methods of shuffling DNA to obtain recombinant herbicide tolerance nucleic acids encoding proteins having new or improved herbicide tolerance activities, libraries of shuffled herbicide tolerance nucleic acids, transgenic plants and DNA shuffling mixtures are provided.
    Type: Application
    Filed: July 25, 2003
    Publication date: March 17, 2005
    Inventors: Venkiteswaran Subramanian, Willem Stemmer, Linda Castle, Umesh Muchhal, Daniel Siehl
  • Interferon variants with improved properties
    Publication number: 20050054053
    Abstract: The invention relates to interferon variants with improved properties and methods for their use.
    Type: Application
    Filed: March 30, 2004
    Publication date: March 10, 2005
    Inventors: Anna Aguinaldo, Amelia Beyna, Ho Cho, John Desjarlais, Shannon Marshall, Umesh Muchhal, Michael Villegas, Eugene Zhukovsky, Michael Quesenberry
  • Interferon variants with improved properties
    Publication number: 20040137581
    Abstract: The invention relates to interferon variants with improved properties and methods for their use.
    Type: Application
    Filed: September 30, 2003
    Publication date: July 15, 2004
    Applicant: Xencor
    Inventors: Anna Marie Aguinaldo, Amelia Joy Beyna, Ho Sung Cho, John Rudolph Desjarlais, Shannon Alicia Marshall, Umesh Muchhal, Michael Francis Aquino Villegas, Eugene Zhukovsky
  • Nucleic acids and proteins with thioredoxin reductase activity
    Publication number: 20030211511
    Abstract: The present invention relates to the use of a variety of methods for generating functional thioredoxin reductase variants in which at least one physical, chemical or biological property of the variant is altered in a specific and desired manner when compared to the wild-type protein.
    Type: Application
    Filed: November 6, 2002
    Publication date: November 13, 2003
    Inventors: Steven P. Briggs, Bipin K. Dalmia, Greg del Val, John R. Desjarlais, Peter Heifetz, Peter Luginbuhl, Umesh Muchhal
  • Protein based TNF-alpha variants for the treatment of TNF-alpha related disorders
    Publication number: 20030138401
    Abstract: The invention relates to novel proteins with TNF-alpha antagonist activity and nucleic acids encoding these proteins. The invention further relates to the use of the novel proteins in the treatment of TNF-alpha related disorders.
    Type: Application
    Filed: September 30, 2002
    Publication date: July 24, 2003
    Inventors: Bassil I. Dahiyat, John R. Desjarlais, Anton Filikov, Umesh Muchhal, Malu Lourdes G. Tansey, Jonathan Zalevsky
  • Nucleic acids and proteins with thioredoxin reductase activity
    Publication number: 20030100743
    Abstract: The present invention relates to the use of a variety of methods for generating functional thioredoxin reductase variants in which at least one physical, chemical or biological property of the variant is altered in a specific and desired manner when compared to the wild-type protein.
    Type: Application
    Filed: May 6, 2002
    Publication date: May 29, 2003
    Inventors: Bipin K. Dalmia, Steven P. Briggs, Greg del Val, John R. Desjarlais, Peter Heifetz, Peter Luginbuhl, Umesh Muchhal