Abstract: The invention concerns a sonocatalyst which is suitable for promoting a chemical reaction initiated by ultrasound irradiation. The invention also relates to a method of catalysing a reaction by exposing the sonocatalyst to ultrasound. The invention also relates to the use of a sonocatalyst as described herein in a method as described herein.

Abstract: Abstract: The present invention provides a core-shell micro-particle comprising a biodegradable polymer with at least two or more surface cavities. The present invention also provides use of the core-shell micro-particle in drug delivery, contrast enhancement, subharmonic imaging enhancement, theranostics, and/or any combination of the aforementioned applications.

Abstract: The present invention provides a core-shell microparticle comprising a biodegradable polymer with at least two or more surface cavities for use in the treatment of vascular disease, wherein the shell further comprises one or more drugs. The present invention further provides a core-shell microparticle which can be used for such treatments, the microparticle comprising a biodegradable polymer with at least two or more surface cavities, wherein the shell further comprises one or more drugs, wherein the one or more drugs are selected from anti-inflammatory drugs, immunosuppressants, anti-proliferative drugs, anti-coagulants and combinations thereof.