Patents by Inventor Umesh Shaligram

Umesh Shaligram has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOGENIC COMPOSITION COMPRISING CYAA-DERIVED POLYPEPTIDE PROMOTING A TH1/TH17-ORIENTED IMMUNE RESPONSE
    Publication number: 20230165950
    Abstract: The invention relates to the use of a polypeptide derived from the adenylate cyclase of a Bordetella sp. (CyaA-derived polypeptide) by deletion of a segment of at least 93 amino acid residues, in particular a polypeptide derived from CyaA of Bordetella pertussis, as an immunomodifying antigen of the TH1/TH17-oriented immune response in an immunogenic composition. The invention relates to a vaccine candidate comprising such CyaA-derived polypeptide, either in an acellular immunogenic composition for active immunization against a condition causally related to the infection of a host by Bordetella sp. or in a combination composition encompassing said acellular immunogenic composition.
    Type: Application
    Filed: July 26, 2022
    Publication date: June 1, 2023
    Inventors: Rémi PALMANTIER, Yolande MISSERI, Caroline DIVEU-SADER, Sunil GAIROLA, Manish GAUTAM, Harish RAO, Umesh SHALIGRAM
  • IMMUNOGENIC COMPOSITION COMPRISING CYAA-DERIVED POLYPEPTIDE PROMOTING A TH1/TH17-ORIENTED IMMUNE RESPONSE
    Publication number: 20190307875
    Abstract: The invention relates to the use of a polypeptide derived from the adenylate cyclase of a Bordetella sp. (CyaA-derived polypeptide) by deletion of a segment of at least 93 amino acid residues, in particular a polypeptide derived from CyaA of Bordetella pertussis, as an immunomodifying antigen of the TH1/TH17-oriented immune response in an immunogenic composition. The invention relates to a vaccine candidate comprising such CyaA-derived polypeptide, either in an acellular immunogenic composition for active immunization against a condition causally related to the infection of a host by Bordetella sp. or in a combination composition encompassing said acellular immunogenic composition.
    Type: Application
    Filed: December 22, 2017
    Publication date: October 10, 2019
    Applicants: GENKYOTEX, SERUM INSTITUTE OF INDIA PRIVATE LIMITED
    Inventors: Rémi PALMANTIER, Yolande MISSERI, Caroline DIVEU-SADER, Sunil GAIROLA, Manish GAUTAM, Harish RAO, Umesh SHALIGRAM
  • Highly pure polysialic acid and process for preparation thereof
    Patent number: 8097437
    Abstract: The instant invention provides highly pure Polysialic acid and process for preparation thereof.
    Type: Grant
    Filed: July 13, 2007
    Date of Patent: January 17, 2012
    Assignee: Serum Institute of India Ltd.
    Inventors: Subhash V. Kapre, Umesh Shaligram
  • HIGHLY PURE POLYSIALIC ACID AND PROCESS FOR PREPERATION THEREOF
    Publication number: 20100086974
    Abstract: The instant invention provides highly pure Polysialic acid and process for preparation thereof.
    Type: Application
    Filed: July 13, 2007
    Publication date: April 8, 2010
    Applicant: Serum Institute of India Ltd.
    Inventors: Subhash V. Kapre, Umesh Shaligram
  • Process for the extraction and isolation of insulin from recombinant sources
    Publication number: 20060167221
    Abstract: The present invention relates to the extraction and isolation of insulins from recombinant sources, particularly those expressed in and secreted by yeasts. Organic solvents have been used to extract host surface bound forms of insulin polypeptide. In addition, procedures for combining the steps medium clarification, solvent extraction and chromatography, in order to effect the simultaneous isolation and purification of soluble and membrane bound forms of insulin, is disclosed.
    Type: Application
    Filed: November 14, 2003
    Publication date: July 27, 2006
    Inventors: Maharaj Sahib, Edupuganti Raju, Umesh Shaligram