Patents by Inventor Un-Kyung Kim

Un-Kyung Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9783590
    Abstract: Identified herein are different forms of bitter receptor genes that occur in different humans. These alleles are generated by numerous coding single nucleotide polymorphisms (cSNP's) that occur within the members of the T2R gene family. Some SNP's cause amino acid substitutions, while others introduce chain termination codons, rendering the allele non-functional. Differences in these genes are believed to have a large effect on those individuals' sense of bitter taste, such that these individuals perceive the taste of bitter substances differently than the rest of the population. The ability to assay this allelic information is useful in the development of flavorings and flavor enhancers, as it can be used to define large groups and populations who perceive bitter tastes differently. This in turn allows the taste preferences of these groups to be addressed at the molecular level for the first time.
    Type: Grant
    Filed: November 12, 2012
    Date of Patent: October 10, 2017
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Dennis Drayna, Un-Kyung Kim
  • Patent number: 8796441
    Abstract: Identified herein are different forms of sweet and umami receptor encoding sequences that occur in different human populations. In particular, there are provided several single nucleotide polymorphisms (SNPs) that occur within the exons/coding sequence (and are therefore coding SNPs, cSNPs) of one of the three T1R genes. Some SNPs cause amino acid substitutions, while others introduce a chain termination codon, rendering a truncated product. Differences in these genes are believed to affect the sense of taste of individuals, such that individuals with different SNPs (or different haplotypes) are believed to perceive the taste of sweet or umami (e.g., glutamate) substances differently than the rest of the population. The ability to assay this allelic information is useful in the development of flavorings and flavor enhancers, as it can be used to define groups and populations who perceive tastes differently. This in turn allows the taste preferences of these groups to be addressed at the molecular level.
    Type: Grant
    Filed: April 13, 2006
    Date of Patent: August 5, 2014
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Dennis T. Drayna, Un-Kyung Kim
  • Patent number: 8309701
    Abstract: Identified herein are different forms of bitter receptor genes that occur in different humans. These alleles are generated by numerous coding single nucleotide polymorphisms (cSNP's) that occur within the members of the T2R gene family. Some SNP's cause amino acid substitutions, while others introduce chain termination codons, rendering the allele non-functional. Differences in these genes are believed to have a large effect on those individuals' sense of bitter taste, such that these individuals perceive the taste of bitter substances differently than the rest of the population. The ability to assay this allelic information is useful in the development of flavorings and flavor enhancers, as it can be used to define large groups and populations who perceive bitter tastes differently. This in turn allows the taste preferences of these groups to be addressed at the molecular level for the first time.
    Type: Grant
    Filed: August 3, 2009
    Date of Patent: November 13, 2012
    Assignee: The United States of America as represented by the Secrectary of the Department of Health and Human Services
    Inventors: Dennis Drayna, Un-Kyung Kim
  • Patent number: 8148082
    Abstract: The invention provides isolated nucleic and amino acid sequences of a taste cell receptor that serves as a sensor for the bitter taste of phenylthiocarbamide (PTC), antibodies to such PTC taste receptor, methods of detecting such nucleic and amino acid sequences, and methods of screening for modulators of such PTC taste receptor.
    Type: Grant
    Filed: January 20, 2010
    Date of Patent: April 3, 2012
    Assignees: The United States of America as represented by the Secretary of the Department of Health and Human Services, The University of Utah Research Foundation
    Inventors: Dennis Drayna, Un-Kyung Kim, Mark Leppert
  • Publication number: 20100151476
    Abstract: The invention provides isolated nucleic and amino acid sequences of a taste cell receptor that serves as a sensor for the bitter taste of phenylthiocarbamide (PTC), antibodies to such PTC taste receptor, methods of detecting such nucleic and amino acid sequences, and methods of screening for modulators of such PTC taste receptor.
    Type: Application
    Filed: January 20, 2010
    Publication date: June 17, 2010
    Inventors: Dennis Drayna, Un-Kyung Kim, Mark Leppert
  • Patent number: 7666601
    Abstract: The invention provides isolated nucleic and amino acid sequences of a taste cell receptor that serves as a sensor for the bitter taste of phenylthiocarbamide (PTC), antibodies to such PTC taste receptor, methods of detecting such nucleic and amino acid sequences, and methods of screening for modulators of such PTC taste receptor.
    Type: Grant
    Filed: October 11, 2007
    Date of Patent: February 23, 2010
    Assignees: The United States of America as represented by the Secretary of the Department of Health and Human Services, The University of Utah Research Foundation
    Inventors: Dennis Drayna, Un-Kyung Kim, Mark Leppert
  • Publication number: 20100035340
    Abstract: Identified herein are different forms of bitter receptor genes that occur in different humans. These alleles are generated by numerous coding single nucleotide polymorphisms (cSNP's) that occur within the members of the T2R gene family. Some SNP's cause amino acid substitutions, while others introduce chain termination codons, rendering the allele non-functional. Differences in these genes are believed to have a large effect on those individuals' sense of bitter taste, such that these individuals perceive the taste of bitter substances differently than the rest of the population. The ability to assay this allelic information is useful in the development of flavorings and flavor enhancers, as it can be used to define large groups and populations who perceive bitter tastes differently. This in turn allows the taste preferences of these groups to be addressed at the molecular level for the first time.
    Type: Application
    Filed: August 3, 2009
    Publication date: February 11, 2010
    Inventors: Dennis Drayna, Un-Kyung Kim
  • Patent number: 7579453
    Abstract: Identified herein are different forms of bitter receptor genes that occur in different humans. These alleles are generated by numerous coding single nucleotide polymorphisms (cSNP's) that occur within the members of the T2R gene family. Some SNP's cause amino acid substitutions, while others introduce chain termination codons, rendering the allele non-functional. Differences in these genes are believed to have a large effect on those individuals' sense of bitter taste, such that these individuals perceive the taste of bitter substances differently than the rest of the population. The ability to assay this allelic information is useful in the development of flavorings and flavor enhancers, as it can be used to define large groups and populations who perceive bitter tastes differently. This in turn allows the taste preferences of these groups to be addressed at the molecular level for the first time.
    Type: Grant
    Filed: June 18, 2004
    Date of Patent: August 25, 2009
    Assignee: The United States of America as represented by the Secretary of the Dapartment of Health and Human Services
    Inventors: Dennis Drayna, Un-Kyung Kim
  • Publication number: 20080287310
    Abstract: Identified herein are different forms of sweet and umami receptor encoding sequences that occur in different human populations. In particular, there are provided several single nucleotide polymorphisms (SNPs) that occur within the exons/coding sequence (and are therefore coding SNPs, cSNPs) of one of the three T1R genes. Some SNPs cause amino acid substitutions, while others introduce a chain termination codon, rendering a truncated product. Differences in these genes are believed to affect the sense of taste of individuals, such that individuals with different SNPs (or different haplotypes) are believed to perceive the taste of sweet or umami (e.g., glutamate) substances differently than the rest of the population. The ability to assay this allelic information is useful in the development of flavorings and flavor enhancers, as it can be used to define groups and populations who perceive tastes differently. This in turn allows the taste preferences of these groups to be addressed at the molecular level.
    Type: Application
    Filed: April 13, 2006
    Publication date: November 20, 2008
    Inventors: Dennis T. Drayna, Un-Kyung Kim
  • Publication number: 20080227093
    Abstract: The invention provides isolated nucleic and amino acid sequences of a taste cell receptor that serves as a sensor for the bitter taste of phenylthiocarbamide (PTC), antibodies to such PTC taste receptor, methods of detecting such nucleic and amino acid sequences, and methods of screening for modulators of such PTC taste receptor.
    Type: Application
    Filed: October 11, 2007
    Publication date: September 18, 2008
    Inventors: Dennis Drayna, Un-Kyung Kim, Mark Leppert
  • Patent number: 7314725
    Abstract: The invention provides isolated nucleic and amino acid sequences of a taste cell receptor that serves as a sensor for the bitter taste of phenylthiocarbamide (PTC), antibodies to such PTC taste receptor, methods of detecting such nucleic and amino acid sequences, and methods of screening for modulators of such PTC taste receptor.
    Type: Grant
    Filed: July 19, 2002
    Date of Patent: January 1, 2008
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Dennis Drayna, Un-Kyung Kim, Mark Leppert
  • Publication number: 20070128604
    Abstract: Identified herein are different forms of bitter receptor genes that occur in different humans. These alleles are generated by numerous coding single nucleotide polymorphisms (cSNP's) that occur within the members of the T2R gene family. Some SNP's cause amino acid substitutions, while others introduce chain termination codons, rendering the allele non-functional. Differences in these genes are believed to have a large effect on those individuals' sense of bitter taste, such that these individuals perceive the taste of bitter substances differently than the rest of the population. The ability to assay this allelic information is useful in the development of flavorings and flavor enhancers, as it can be used to define large groups and populations who perceive bitter tastes differently. This in turn allows the taste preferences of these groups to be addressed at the molecular level for the first time.
    Type: Application
    Filed: June 18, 2004
    Publication date: June 7, 2007
    Applicant: THE GOVT. OF THE U. S. A. AS REPRESENTED BY THE SEC. OF DEPT. OF HEALTH AND HUMAN SERVICES
    Inventors: Dennis Drayna, Un-Kyung Kim
  • Publication number: 20040248123
    Abstract: The invention provides isolated nucleic and amino acid sequences of a taste cell receptor that serves as a sensor for the bitter taste of phenylthiocarbamide (PTC), antibodies to such PTC taste receptor, methods of detecting such nucleic and amino acid sequences, and methods of screening for modulators of such PTC taste receptor.
    Type: Application
    Filed: January 20, 2004
    Publication date: December 9, 2004
    Inventors: Dennis Drayna, Un-Kyung Kim, Mark Leppert