Patents by Inventor Un-Kyung Kim
Un-Kyung Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 9783590Abstract: Identified herein are different forms of bitter receptor genes that occur in different humans. These alleles are generated by numerous coding single nucleotide polymorphisms (cSNP's) that occur within the members of the T2R gene family. Some SNP's cause amino acid substitutions, while others introduce chain termination codons, rendering the allele non-functional. Differences in these genes are believed to have a large effect on those individuals' sense of bitter taste, such that these individuals perceive the taste of bitter substances differently than the rest of the population. The ability to assay this allelic information is useful in the development of flavorings and flavor enhancers, as it can be used to define large groups and populations who perceive bitter tastes differently. This in turn allows the taste preferences of these groups to be addressed at the molecular level for the first time.Type: GrantFiled: November 12, 2012Date of Patent: October 10, 2017Assignee: The United States of America as represented by the Secretary of the Department of Health and Human ServicesInventors: Dennis Drayna, Un-Kyung Kim
-
Patent number: 8796441Abstract: Identified herein are different forms of sweet and umami receptor encoding sequences that occur in different human populations. In particular, there are provided several single nucleotide polymorphisms (SNPs) that occur within the exons/coding sequence (and are therefore coding SNPs, cSNPs) of one of the three T1R genes. Some SNPs cause amino acid substitutions, while others introduce a chain termination codon, rendering a truncated product. Differences in these genes are believed to affect the sense of taste of individuals, such that individuals with different SNPs (or different haplotypes) are believed to perceive the taste of sweet or umami (e.g., glutamate) substances differently than the rest of the population. The ability to assay this allelic information is useful in the development of flavorings and flavor enhancers, as it can be used to define groups and populations who perceive tastes differently. This in turn allows the taste preferences of these groups to be addressed at the molecular level.Type: GrantFiled: April 13, 2006Date of Patent: August 5, 2014Assignee: The United States of America as represented by the Secretary of the Department of Health and Human ServicesInventors: Dennis T. Drayna, Un-Kyung Kim
-
Patent number: 8309701Abstract: Identified herein are different forms of bitter receptor genes that occur in different humans. These alleles are generated by numerous coding single nucleotide polymorphisms (cSNP's) that occur within the members of the T2R gene family. Some SNP's cause amino acid substitutions, while others introduce chain termination codons, rendering the allele non-functional. Differences in these genes are believed to have a large effect on those individuals' sense of bitter taste, such that these individuals perceive the taste of bitter substances differently than the rest of the population. The ability to assay this allelic information is useful in the development of flavorings and flavor enhancers, as it can be used to define large groups and populations who perceive bitter tastes differently. This in turn allows the taste preferences of these groups to be addressed at the molecular level for the first time.Type: GrantFiled: August 3, 2009Date of Patent: November 13, 2012Assignee: The United States of America as represented by the Secrectary of the Department of Health and Human ServicesInventors: Dennis Drayna, Un-Kyung Kim
-
Patent number: 8148082Abstract: The invention provides isolated nucleic and amino acid sequences of a taste cell receptor that serves as a sensor for the bitter taste of phenylthiocarbamide (PTC), antibodies to such PTC taste receptor, methods of detecting such nucleic and amino acid sequences, and methods of screening for modulators of such PTC taste receptor.Type: GrantFiled: January 20, 2010Date of Patent: April 3, 2012Assignees: The United States of America as represented by the Secretary of the Department of Health and Human Services, The University of Utah Research FoundationInventors: Dennis Drayna, Un-Kyung Kim, Mark Leppert
-
Publication number: 20100151476Abstract: The invention provides isolated nucleic and amino acid sequences of a taste cell receptor that serves as a sensor for the bitter taste of phenylthiocarbamide (PTC), antibodies to such PTC taste receptor, methods of detecting such nucleic and amino acid sequences, and methods of screening for modulators of such PTC taste receptor.Type: ApplicationFiled: January 20, 2010Publication date: June 17, 2010Inventors: Dennis Drayna, Un-Kyung Kim, Mark Leppert
-
Patent number: 7666601Abstract: The invention provides isolated nucleic and amino acid sequences of a taste cell receptor that serves as a sensor for the bitter taste of phenylthiocarbamide (PTC), antibodies to such PTC taste receptor, methods of detecting such nucleic and amino acid sequences, and methods of screening for modulators of such PTC taste receptor.Type: GrantFiled: October 11, 2007Date of Patent: February 23, 2010Assignees: The United States of America as represented by the Secretary of the Department of Health and Human Services, The University of Utah Research FoundationInventors: Dennis Drayna, Un-Kyung Kim, Mark Leppert
-
Publication number: 20100035340Abstract: Identified herein are different forms of bitter receptor genes that occur in different humans. These alleles are generated by numerous coding single nucleotide polymorphisms (cSNP's) that occur within the members of the T2R gene family. Some SNP's cause amino acid substitutions, while others introduce chain termination codons, rendering the allele non-functional. Differences in these genes are believed to have a large effect on those individuals' sense of bitter taste, such that these individuals perceive the taste of bitter substances differently than the rest of the population. The ability to assay this allelic information is useful in the development of flavorings and flavor enhancers, as it can be used to define large groups and populations who perceive bitter tastes differently. This in turn allows the taste preferences of these groups to be addressed at the molecular level for the first time.Type: ApplicationFiled: August 3, 2009Publication date: February 11, 2010Inventors: Dennis Drayna, Un-Kyung Kim
-
Patent number: 7579453Abstract: Identified herein are different forms of bitter receptor genes that occur in different humans. These alleles are generated by numerous coding single nucleotide polymorphisms (cSNP's) that occur within the members of the T2R gene family. Some SNP's cause amino acid substitutions, while others introduce chain termination codons, rendering the allele non-functional. Differences in these genes are believed to have a large effect on those individuals' sense of bitter taste, such that these individuals perceive the taste of bitter substances differently than the rest of the population. The ability to assay this allelic information is useful in the development of flavorings and flavor enhancers, as it can be used to define large groups and populations who perceive bitter tastes differently. This in turn allows the taste preferences of these groups to be addressed at the molecular level for the first time.Type: GrantFiled: June 18, 2004Date of Patent: August 25, 2009Assignee: The United States of America as represented by the Secretary of the Dapartment of Health and Human ServicesInventors: Dennis Drayna, Un-Kyung Kim
-
Publication number: 20080287310Abstract: Identified herein are different forms of sweet and umami receptor encoding sequences that occur in different human populations. In particular, there are provided several single nucleotide polymorphisms (SNPs) that occur within the exons/coding sequence (and are therefore coding SNPs, cSNPs) of one of the three T1R genes. Some SNPs cause amino acid substitutions, while others introduce a chain termination codon, rendering a truncated product. Differences in these genes are believed to affect the sense of taste of individuals, such that individuals with different SNPs (or different haplotypes) are believed to perceive the taste of sweet or umami (e.g., glutamate) substances differently than the rest of the population. The ability to assay this allelic information is useful in the development of flavorings and flavor enhancers, as it can be used to define groups and populations who perceive tastes differently. This in turn allows the taste preferences of these groups to be addressed at the molecular level.Type: ApplicationFiled: April 13, 2006Publication date: November 20, 2008Inventors: Dennis T. Drayna, Un-Kyung Kim
-
Publication number: 20080227093Abstract: The invention provides isolated nucleic and amino acid sequences of a taste cell receptor that serves as a sensor for the bitter taste of phenylthiocarbamide (PTC), antibodies to such PTC taste receptor, methods of detecting such nucleic and amino acid sequences, and methods of screening for modulators of such PTC taste receptor.Type: ApplicationFiled: October 11, 2007Publication date: September 18, 2008Inventors: Dennis Drayna, Un-Kyung Kim, Mark Leppert
-
Patent number: 7314725Abstract: The invention provides isolated nucleic and amino acid sequences of a taste cell receptor that serves as a sensor for the bitter taste of phenylthiocarbamide (PTC), antibodies to such PTC taste receptor, methods of detecting such nucleic and amino acid sequences, and methods of screening for modulators of such PTC taste receptor.Type: GrantFiled: July 19, 2002Date of Patent: January 1, 2008Assignee: The United States of America as represented by the Secretary of the Department of Health and Human ServicesInventors: Dennis Drayna, Un-Kyung Kim, Mark Leppert
-
Publication number: 20070128604Abstract: Identified herein are different forms of bitter receptor genes that occur in different humans. These alleles are generated by numerous coding single nucleotide polymorphisms (cSNP's) that occur within the members of the T2R gene family. Some SNP's cause amino acid substitutions, while others introduce chain termination codons, rendering the allele non-functional. Differences in these genes are believed to have a large effect on those individuals' sense of bitter taste, such that these individuals perceive the taste of bitter substances differently than the rest of the population. The ability to assay this allelic information is useful in the development of flavorings and flavor enhancers, as it can be used to define large groups and populations who perceive bitter tastes differently. This in turn allows the taste preferences of these groups to be addressed at the molecular level for the first time.Type: ApplicationFiled: June 18, 2004Publication date: June 7, 2007Applicant: THE GOVT. OF THE U. S. A. AS REPRESENTED BY THE SEC. OF DEPT. OF HEALTH AND HUMAN SERVICESInventors: Dennis Drayna, Un-Kyung Kim
-
Publication number: 20040248123Abstract: The invention provides isolated nucleic and amino acid sequences of a taste cell receptor that serves as a sensor for the bitter taste of phenylthiocarbamide (PTC), antibodies to such PTC taste receptor, methods of detecting such nucleic and amino acid sequences, and methods of screening for modulators of such PTC taste receptor.Type: ApplicationFiled: January 20, 2004Publication date: December 9, 2004Inventors: Dennis Drayna, Un-Kyung Kim, Mark Leppert