Abstract: A method for obtaining a three-dimensional velocity measurement of a tissue from an ultrasound device comprising generating a set of correlation-velocity transfer functions from a first image plane and a second image plane, each image plane characterizing the tissue, wherein the set of correlation-velocity transfer functions can be applied to situations of constant ultrasound beam profile and/or periodic flow patterns; collecting, using the ultrasound device, an ultrasound measurement image; determining a set of in-plane velocity vectors and a set of speckle correlation values mapped to the ultrasound measurement image; determining a set of out-of-plane velocity vectors, corresponding to the set of in-plane velocity vectors, by applying the set of correlation-velocity transfer functions to the set of speckle correlation values; and generating, for the ultrasound measurement image, a three-dimensional velocity measurement from the sets of in-plane and out-of-plane velocity vectors.