Abstract: Disclosed herein is a marker flange for use with a brachytherapy applicator, having a flange body with a first face, a second face, and a hollow chamber positioned between the first and second faces. A cavity extending through the flange body is dimensioned to receive a tandem in a brachytherapy applicator in a press-fit connection, so as to affix the flange-marker to an outside surface of the tandem. The hollow chamber includes an MR imaging responsive marker agent that provides strong signal intensities and a high geometric accuracy in MR imaging.

Abstract: A personally portable nanoparticle respiratory deposition (NRD) sampler configured to collect nanoparticles based upon a sampling criterion. In an aspect, the NRD sampler has an impactor stage, and a diffusion stage. In another aspect, the NRD sampler includes a particle size separator in addition to an impactor stage and a diffusion stage.

Abstract: The invention provides compounds of formula I: or salts thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula I and therapeutic methods for treating cancer.

Abstract: The present disclosure provides targeting peptides and vectors containing a sequence that encodes targeting peptides that deliver agents to the brain.

Abstract: Provided are methods for determining optimal features for classifying patterns or objects. Also provided are methods for image analysis. Further provided are methods for image searching.

Abstract: The present invention is directed to small interfering RNA molecules (siRNA) targeted against an allele of interest, and methods of using these siRNA molecules.