Abstract: A device circles the spinal segmental nerves like a ring and cause stimulation of the nerves. The present invention offers magnetic as well as electric stimulation properties in order to balance the two modes.

Abstract: A laser system for changing the index of refraction of cornea tissue in a living eye. The laser system comprises a laser that provides laser pulses with a wavelength from 400 nm to 900 nm and a pulse energy from 0.01 nJ to 10 nJ, and a control device for setting the operating parameters of the laser below an optical breakdown threshold of the tissue to avoid photo-disruption and tissue destruction of the tissue, and to direct the laser pulses at the cornea tissue resulting in a change in the index of refraction of the tissue within regions irradiated by the laser pulses.

Abstract: Tools in the form of hardware apparatus, software components, a system comprising hardware apparatus and software components, methods, and applications of said system and methods, which pertain to and enable the analysis of and reporting about the process of composing written material; i.e., the process of writing. An important and distinguishing attribute of at least certain aspects of the embodied invention is its utilization of software that unobtrusively measures and reports on how people write; i.e., again, the process of writing.

Abstract: An epidermal sample is placed into a sample holder formed as a sandwich assembly. The sample holder is placed in an upper well within a lower well to be exposed to media in both wells. Properties of the sample can be studied, such as paracellular flux, transepidermal electric resistance, reaction to compounds, and epidermal barrier recovery.

Abstract: The present invention relates to a medical support device and uses thereof. The medical support device includes a stem defining a longitudinal axis, the stem having an upper end and a lower end, the lower end adapted for securing the device to a receptacle. The medical support device also includes an elongate member permanently secured to the stem and extending outwardly from said stem at an angle to the longitudinal axis, the elongate member having an end proximate to said stem and an end distal to said stem, and a plurality of medical equipment support elements fixed to a lower surface of the elongate member between the distal end and a point intermediate the proximal and distal ends.

Abstract: Integrated multi-criteria decision frameworks disclosed herein can facilitate making good decisions when faced with a complex choice among several alternatives with different combinations of strengths and weaknesses. Some decision support systems using multi-criteria methods can combine multiple multi-criteria methods in a single adaptable decision support intervention. In some embodiments, the framework can include some or all of the following modules: a decision strategy module; a balance sheet module; an interactive decision dashboard module; an ordinal ranking module; a direct weighting module; and an Analytic Hierarchy Process (AHP) module.

Abstract: An energy-efficient CAM architecture provides increased speed of searching, reduced power consumption, or a tuned combination of increased speed of searching and reduced power consumption. The CAM comprises a plurality of CAM banks, a plurality of Bloom filters, each Bloom filter associated with a content addressable memory bank, each Bloom filter recording elements inserted into an associated content addressable memory bank, wherein the size of each Bloom filter is configured to reduce energy or power consumption of the content addressable memory apparatus. The size of each Bloom filter may be configured to reduce energy or power consumption of the content addressable memory apparatus.

Abstract: A laser system for modifying the index of refraction of an optical hydrogel material. The laser system comprises a computer program to determine the position and shape of refractive structures to be written into the optical hydrogel material to correct a patient's vision, and a focused laser that generates laser light having a wavelength of from 400 nm to 900 nm, and which operates with an average power of 10 mW to 1000 mW to produce a pulse energy from 0.05 nJ to 1000 nJ with a peak intensity at focus of greater than 1013 W/cm2. The refractive structures exhibit a change in the index of refraction of 0.01 to 0.06 in the optical hydrogel material.

Abstract: Disclosed is a computer-implemented method for correcting refractive errors in a living eye using a laser vision correction system that involves first calculating an amount of sphere based on preoperative manifest refraction and higher order aberrations data associated with the eye, and then correcting for the calculated amount of sphere by ablating at least a portion of the eye. The preoperative manifest refraction may include preoperative manifest sphere, preoperative spherical equivalent, regular astigmatism, and oblique astigmatism, and the preoperative higher-order aberrations may include 4th-order spherical and 3rd root mean square. Other factors may also be used to adjust the calculated amount of sphere. A device readable medium for storing the calculation and instructions for operating a laser vision correction system for practicing the method is also disclosed, as is a method of treating refractive errors.

Abstract: The present invention relates to methods for identifying agents which bind to specific amino acid residues of the protein interaction site of G protein ? protein subunit. Compounds identified in accordance with the assay of the invention and methods for using the compound for modulating at least one activity of a G protein are also provided.

Abstract: The prostate gland or other region of interest is stimulated with laser light, resulting in ultrasound waves (photoacoustic effect) which are focused by an acoustic lens and captured by a specific 1- or 2D sensor array and subsequently displayed as a C-scan on a computer screen. The amplitude of the ultrasound waves generated by laser stimulation is proportional to the optical absorption of the tissue element at that spatial location. Variability in tissue absorption results in C-scan image contrast. The photoacoustic imaging is combined with an ultrasound C-scan image produced with a plane ultrasound wave applied to the region of interest.

Abstract: A new framework for extending monochrome barcodes to color is provided. The new framework offers higher data rates and enables new functionalities than are available with conventional monochrome barcodes. In an embodiment of the present invention, the framework encodes independent data in each of the cyan, magenta, and yellow print colorant channels commonly used in color printing and decodes the data from each of the complementary red, green, and blue channels in capture color channels. The framework effectively increases the capacity of monochrome barcodes by a factor of three. In an embodiment of the present invention, a physical model based approach is adopted to mitigate the effect of cross-channel interference among the print-colorant channels and capture color channels. In an embodiment of the invention, a pilot block methodology is proposed to estimate the model parameters and enable cross-channel interference cancellation.

Abstract: The present invention relates to a recombinant factor VIII that includes one or more mutations that result in enhanced stability of both factor VIII and factor VIIIa. Methods of making and using the recombinant factor VIII, and pharmaceutical compositions containing the same are also disclosed. The present invention further relates to an isolated nucleic acid molecule that encodes the recombinant factor VIII, as well as DNA expression systems and host cells containing the isolated nucleic acid molecule.

Abstract: The invention relates to a microfluidic device that utilizes nucleic acid-based detection and a detection system containing the same, as well as a process for preparing the micro fluidic device and for using the same to detect the presence of a target nucleic acid molecule in a sample.

Abstract: Embodiments of the invention are directed to a new type of phase screen, i.e., an opto-electronic device that can convert a distorted incoming optical wavefront into a plane wave or, conversely, transform a plane wave into a prescribed varying output wavefront. The basic concept involves novel binary all-digital MEMS interferometer configurations that can be used to create controlled and arbitrary optical wavefront using only 0,1 amplitude changes followed by differential propagation distances to convert these amplitude variations into controllable and/or continuous phase variations. Clustered pixel notions, such as Floyd-Steinberg, Stucki or other algorithms useful in digital half-tone printing, are simultaneously employed to create controllable grey-level variations as well as continuous phase variations. Desired grey-levels can be obtained wherein each pixel is formed by, e.g., a 3×3 or 5×5 cluster of mirrors.