Patents by Inventor Upamali Perera

Upamali Perera has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for identifying and treating invasive/metastatic breast cancers
    Patent number: 10443054
    Abstract: Cancer invasion is a hallmark of metastasis. The mesenchymal mode of cancer cell invasion is mediated by elongated membrane protrusions driven by the assembly of branched F-actin networks. Described herein are compositions and methods for assessing and treating a subject having metastatic cancer or at risk of developing metastatic cancer, e.g., metastatic breast cancer, through the determination of Lamellipodin protein or gene expression levels in the subject.
    Type: Grant
    Filed: March 6, 2017
    Date of Patent: October 15, 2019
    Assignees: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, KING'S COLLEGE LONDON
    Inventors: Frank B. Gertler, Guillaume Carmona, Matthias Krause, Upamali Perera
  • METHODS FOR IDENTIFYING AND TREATING INVASIVE/METASTATIC CANCERS
    Publication number: 20170269093
    Abstract: Cancer invasion is a hallmark of metastasis. The mesenchymal mode of cancer cell invasion is mediated by elongated membrane protrusions driven by the assembly of branched F-actin networks. Described herein are compositions and methods for assessing and treating a subject having metastatic cancer or at risk of developing metastatic cancer, e.g., metastatic breast cancer, through the determination of Lamellipodin protein or gene expression levels in the subject.
    Type: Application
    Filed: March 6, 2017
    Publication date: September 21, 2017
    Inventors: Frank B. Gertler, Guillaume Carmona, Matthias Krause, Upamali Perera