Patents by Inventor Upendra K. Kar

Upendra K. Kar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vault complexes for cytokine delivery
    Patent number: 11793860
    Abstract: The invention relates to compositions of vault complexes containing recombinant cytokine fusion proteins that include a cytokine and a vault targeting domain, and methods of using the vault complexes to deliver the cytokines to a cell or subject, and methods for using the compositions to treat cancer, such as lung cancer.
    Type: Grant
    Filed: August 12, 2020
    Date of Patent: October 24, 2023
    Assignees: The Regents of the University of California, The United States Government as Represented by the Department of Veterans Affairs
    Inventors: Leonard H. Rome, Valerie Ann Kickhoefer, Steven M. Dubinett, Sherven Sharma, Upendra K. Kar
  • Vault Complexes for Cytokine Delivery
    Publication number: 20200368319
    Abstract: The invention relates to compositions of vault complexes containing recombinant cytokine fusion proteins that include a cytokine and a vault targeting domain, and methods of using the vault complexes to deliver the cytokines to a cell or subject, and methods for using the compositions to treat cancer, such as lung cancer.
    Type: Application
    Filed: August 12, 2020
    Publication date: November 26, 2020
    Inventors: Leonard H. Rome, Valerie Ann Kickhoefer, Steven M. Dubinett, Sherven Sharma, Upendra K. Kar
  • Vault complexes for cytokine delivery
    Patent number: 10780147
    Abstract: The invention relates to compositions of vault complexes containing recombinant cytokine fusion proteins that include a cytokine and a vault targeting domain, and methods of using the vault complexes to deliver the cytokines to a cell or subject, and methods for using the compositions to treat cancer, such as lung cancer.
    Type: Grant
    Filed: February 3, 2017
    Date of Patent: September 22, 2020
    Assignees: The Regents of the University of California, The United States Government as Represented by the Department of Veterans Affairs
    Inventors: Leonard H. Rome, Valerie A. Kickhoefer, Steven M. Dubinett, Sherven Sharma, Upendra K. Kar
  • Vault immunotherapy
    Patent number: 10166277
    Abstract: The invention relates to compositions of vault complexes for use as adjuvants for stimulating a cellular immune response to an antigen, for example a tumor antigen, and methods of using the vault complexes in the treatment of diseases, such as cancer.
    Type: Grant
    Filed: September 5, 2016
    Date of Patent: January 1, 2019
    Assignees: The Regents of the University of California, The United States of America represented by the Department of Veterans Affairs
    Inventors: Leonard H. Rome, Valerie A. Kickhoefer, Sherven Sharma, Steven M. Dubinett, Isaac Yang, Linda M. Liau, Kathleen A. Kelly, Jian Yang, Upendra K. Kar, Cheryl Champion, Janina Jiang
  • Vault Complexes for Cytokine Delivery
    Publication number: 20170143797
    Abstract: The invention relates to compositions of vault complexes containing recombinant cytokine fusion proteins that include a cytokine and a vault targeting domain, and methods of using the vault complexes to deliver the cytokines to a cell or subject, and methods for using the compositions to treat cancer, such as lung cancer.
    Type: Application
    Filed: February 3, 2017
    Publication date: May 25, 2017
    Applicants: The Regents of the University of California, The United States Government as represented by the Department of Veterans Affairs
    Inventors: Leonard H. Rome, Ph.D., Valerie A. Kickhoefer, Steven M. Dubinett, Sherven Sharma, Upendra K. Kar
  • Vault complexes for cytokine delivery
    Patent number: 9597372
    Abstract: The invention relates to compositions of vault complexes containing recombinant cytokine fusion proteins that include a cytokine and a vault targeting domain, and methods of using the vault complexes to deliver the cytokines to a cell or subject, and methods for using the compositions to treat cancer, such as lung cancer.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: March 21, 2017
    Assignees: The Regents of the University of California, The United States of America as represented by the Department of Veterans Affairs
    Inventors: Leonard H. Rome, Valerie A. Kickhoefer, Steven M. Dubinett, Sherven Sharma, Upendra K. Kar
  • Vault Immunotherapy
    Publication number: 20160367653
    Abstract: The invention relates to compositions of vault complexes for use as adjuvants for stimulating a cellular immune response to an antigen, for example a tumor antigen, and methods of using the vault complexes in the treatment of diseases, such as cancer.
    Type: Application
    Filed: September 5, 2016
    Publication date: December 22, 2016
    Inventors: Leonard H. Rome, Valerie A. Kickhoefer, Sherven Sharma, Steven M. Dubinett, Isaac Yang, Linda M. Liau, Kathleen A. Kelly, Jian Yang, Upendra K. Kar, Cheryl Champion, Janina Jiang
  • Vault Immunotherapy
    Publication number: 20150150821
    Abstract: The invention relates to compositions of vault complexes for use as adjuvants for stimulating a cellular immune response to an antigen, for example a tumor antigen, and methods of using the vault complexes in the treatment of diseases, such as cancer.
    Type: Application
    Filed: July 9, 2013
    Publication date: June 4, 2015
    Inventors: Leonard H. Rome, Valerie A. Kickhoefer, Sherven Sharma, Steven M. Dubinett, Isaac Yang, Linda M. Liau, Kathleen A. Kelly, Jian Yang, Upendra K. Kar, Cheryl Champion, Janina Jiang
  • Vault Complexes for Cytokine Delivery
    Publication number: 20150150944
    Abstract: The invention relates to compositions of vault complexes containing recombinant cytokine fusion proteins that include a cytokine and a vault targeting domain, and methods of using the vault complexes to deliver the cytokines to a cell or subject, and methods for using the compositions to treat cancer, such as lung cancer.
    Type: Application
    Filed: November 25, 2014
    Publication date: June 4, 2015
    Applicants: The Regents of the University of California, The United States Government Represented by the Department of Veterans Affairs
    Inventors: Leonard H. Rome, Valerie A. Kickhoefer, Steven M. Dubinett, Sherven Sharma, Upendra K. Kar
  • Vault complexes for cytokine delivery
    Patent number: 8920807
    Abstract: The invention relates to compositions of vault complexes containing recombinant cytokine fusion proteins that include a cytokine and a vault targeting domain, and methods of using the vault complexes to deliver the cytokines to a cell or subject, and methods for using the compositions to treat cancer, such as lung cancer.
    Type: Grant
    Filed: November 2, 2010
    Date of Patent: December 30, 2014
    Assignees: The Regents of the University of California, The United States of America Represented by the Department of Veterans Affairs
    Inventors: Leonard H. Rome, Valerie A. Kickhoefer, Steven M. Dubinett, Sherven Sharma, Upendra K. Kar
  • VAULT COMPLEXES FOR CYTOKINE DELIVERY
    Publication number: 20120213809
    Abstract: The invention relates to compositions of vault complexes containing recombinant cytokine fusion proteins that include a cytokine and a vault targeting domain, and methods of using the vault complexes to deliver the cytokines to a cell or subject, and methods for using the compositions to treat cancer, such as lung cancer.
    Type: Application
    Filed: November 2, 2010
    Publication date: August 23, 2012
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Leonard H. Rome, Valerie A. Kickhoefer, Steven M. Dubinett, Sherven Sharma, Upendra K. Kar