Patents by Inventor Upkar Bhardwaj

Upkar Bhardwaj has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immediate release 4-methyl-3-4[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol-1-YL)-3-(trifluoromethyl)phenyl] benzamide formulation
    Patent number: 9301957
    Abstract: A solid dosage form of nilotinib is disclosed that comprises: (i) a core comprising 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl]benzamide or a pharmaceutically acceptable salt thereof and excipients; and (ii) at least one polymer, said polymer coating said core, wherein disintegration of said solid dosage form is delayed.
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: April 5, 2016
    Assignee: Novartis AG
    Inventors: Upkar Bhardwaj, Ann Reese Comfort, Ping Li, Shoufeng Li, Alexey Makarov, Mangesh Sadashiv Bordawekar
  • IMMEDIATE RELEASE 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl] benzamide FORMULATION
    Publication number: 20150320749
    Abstract: A solid dosage form of nilotinib is disclosed that comprises: (i) a core comprising 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1 H-imidazol-1-yl)-3-(trifluoromethyl)phenyl] benzamide or a pharmaceutically acceptable salt thereof and excipients; and (ii) at least one polymer, said polymer coating said core, wherein disintegration of said solid dosage form is delayed
    Type: Application
    Filed: May 9, 2014
    Publication date: November 12, 2015
    Inventors: Upkar Bhardwaj, Ann Reese Comfort, Ping Li, Shoufeng Li, Alexey Makarov, Mangesh Sadashiv Bordawekar
  • Dialysis adapter cell and method of release testing of a disperse dosage form
    Patent number: 8318506
    Abstract: A dialysis adapter cell includes a housing comprising a plurality of pillars extending between and attached to a top plate and a bottom plate to form a hollow receptacle, wherein the top plate comprises an aperture configured to provide access to the hollow receptacle; a dialysis membrane disposed about the housing and sealingly engaged to the top plate and the bottom plate; and a platform in physical communication with the bottom plate and configured to position the dialysis adapter cell in a sample holder of a United States Pharmacopoeia dissolution apparatus 4 flow-through cell.
    Type: Grant
    Filed: March 1, 2010
    Date of Patent: November 27, 2012
    Assignee: The University of Connecticut
    Inventors: Diane J. Burgess, Upkar Bhardwaj
  • DIALYSIS ADAPTER CELL AND METHOD OF USE
    Publication number: 20100221838
    Abstract: A dialysis adapter cell includes a housing comprising a plurality of pillars extending between and attached to a top plate and a bottom plate to form a hollow receptacle, wherein the top plate comprises an aperture configured to provide access to the hollow receptacle; a dialysis membrane disposed about the housing and sealingly engaged to the top plate and the bottom plate; and a platform in physical communication with the bottom plate and configured to position the dialysis adapter cell in a sample holder of a United States Pharmacopoeia dissolution apparatus 4 flow-through cell.
    Type: Application
    Filed: March 1, 2010
    Publication date: September 2, 2010
    Applicant: UNIVERSITY OF CONNECTICUT
    Inventors: Diane J. Burgess, Upkar Bhardwaj