Patents by Inventor Upneet Sokhi

Upneet Sokhi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210147502
    Abstract: Recombinant therapeutic cytokines (“therakines”) for the treatment of cancer are provided. The recombinant therakines include a truncated region of MDA-7/TL-24 (“M4”) not normally found in nature that has anti-cancer activity and a secretory signal which causes secretion of the therakine from plasmid/virus transduced normal and cancer cells and interaction of the therakine to MDA-7/IL-24 receptors on adjacent, neighboring and distant cancer cells. Therakine interaction results in bystander killing of the target cancer cell as well as adjacent, neighboring and distant cancer cells.
    Type: Application
    Filed: October 28, 2020
    Publication date: May 20, 2021
    Inventors: Paul B. Fisher, Praveen Bhoopathi, Swadesh K. Das, Luni Emdad, Devanand Sarkar, Upneet Sokhi
  • Publication number: 20180305429
    Abstract: Recombinant therapeutic cytokines (“therakines”) for the treatment of cancer are provided. The recombinant therakines include a truncated region of MDA-7/TL-24 (“M4”) not normally found in nature that has anti-cancer activity and a secretory signal which causes secretion of the therakine from plasmid/virus transduced normal and cancer cells and interaction of the therakine to MDA-7/IL-24 receptors on adjacent, neighboring and distant cancer cells. Therakine interaction results in bystander killing of the target cancer cell as well as adjacent, neighboring and distant cancer cells.
    Type: Application
    Filed: April 18, 2018
    Publication date: October 25, 2018
    Inventors: Paul B. Fisher, Praveen Bhoopathi, Swadesh K. Das, Luni Emdad, Devanand Sarkar, Upneet Sokhi
  • Patent number: 9951114
    Abstract: Recombinant therapeutic cytokines (“therakines”) for the treatment of cancer are provided. The recombinant therakines include a truncated region of MDA-7/TL-24 (“M4”) not normally found in nature that has anti-cancer activity and a secretory signal which causes secretion of the therakine from plasmid/virus transduced normal and cancer cells and interaction of the therakine to MDA-7/IL-24 receptors on adjacent, neighboring and distant cancer cells. Therakine interaction results in bystander killing of the target cancer cell as well as adjacent, neighboring and distant cancer cells.
    Type: Grant
    Filed: June 4, 2014
    Date of Patent: April 24, 2018
    Assignee: Virginia Commonwealth University
    Inventors: Paul B. Fisher, Praveen Bhoopathi, Swadesh K. Das, Luni Emdad, Devanand Sarkar, Upneet Sokhi
  • Publication number: 20160108101
    Abstract: Recombinant therapeutic cytokines (“therakines”) for the treatment of cancer are provided. The recombinant therakines include a truncated region of MDA-7/TL-24 (“M4”) not normally found in nature that has anti-cancer activity and a secretory signal which causes secretion of the therakine from plasmid/virus transduced normal and cancer cells and interaction of the therakine to MDA-7/IL-24 receptors on adjacent, neighboring and distant cancer cells. Therakine interaction results in bystander killing of the target cancer cell as well as adjacent, neighboring and distant cancer cells.
    Type: Application
    Filed: June 4, 2014
    Publication date: April 21, 2016
    Inventors: Paul B. Fisher, Praveen Bhoopathi, Swadesh K. Das, Luni Emdad, Devanand Sarkar, Upneet Sokhi