Patents by Inventor Upul Bandarage

Upul Bandarage has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrrole compounds useful as kinase inhibitors
    Publication number: 20060173055
    Abstract: The present invention relates to compounds useful of inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds, processes for making the compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
    Type: Application
    Filed: March 22, 2006
    Publication date: August 3, 2006
    Inventors: Alex Aronov, Upul Bandarage, David Lauffer, Pan Li, Ronald Tomlinson
  • Ion channel modulators and methods of use
    Publication number: 20060160817
    Abstract: In general, the invention relates to compounds useful as ion channel modulators. It has now been found that compounds of this invention, and pharmaceutically acceptable compositions thereof, are useful as inhibitors of voltage-gated sodium channels and/or calcium channels.
    Type: Application
    Filed: November 3, 2005
    Publication date: July 20, 2006
    Inventors: Esther Martinborough, Nicole Zimmermann, Robert Perni, Michael Arnost, Upul Bandarage, Francois Maltais, Guy Bemis
  • Bicyclic inhibitors of Rho kinase
    Publication number: 20060122185
    Abstract: The present invention relates to compounds useful as inhibitors of protein kinases, particularly of ROCK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
    Type: Application
    Filed: November 22, 2005
    Publication date: June 8, 2006
    Inventors: Jeremy Green, Jingrong Cao, Upul Bandarage, Huai Gao, Cornelia Forster
  • Azaindoles useful as inhibitors of rock and other protein kinases
    Publication number: 20060003968
    Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
    Type: Application
    Filed: April 4, 2005
    Publication date: January 5, 2006
    Inventors: Jeremy Green, Andrew Miller, Juan-Miguel Jimenez, Craig Marhefka, Jingrong Cao, John Court, Upul Bandarage, Huai Gao, Suganthini Nanthakumar
  • 3, 10, and 12a Substituted tetracycline compounds
    Publication number: 20050288262
    Abstract: The present invention pertains to novel 3, 10, and/or 12a-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: February 28, 2005
    Publication date: December 29, 2005
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Upul Bandarage, Jackson Chen, Mohamed Ismail, Mark Nelson, Kwasi Ohemeng
  • Pyrrole compositions useful as inhibitors of c-Met
    Publication number: 20050101650
    Abstract: The present invention relates to compounds useful of inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds, processes for making the compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
    Type: Application
    Filed: August 16, 2004
    Publication date: May 12, 2005
    Inventors: Alex Aronov, Upul Bandarage, David Lauffer, Pan Li, Ronald Tomlinson
  • Substituted tetracycline compounds
    Publication number: 20050038002
    Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: December 18, 2003
    Publication date: February 17, 2005
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Mark Nelson, Kwasi Ohemeng, Roger Frechette, Paul Abato, Victor Amoo, Upul Bandarage, Joel Berniac, Beena Bhatia, Jackson Chen, Mohamed Ismail, Oak Kim, Laura Honeyman, Rachid Mechiche, Andre Pearson, Laxma Nagavelli, Paul Sheahan, Atul Verma, Peter Viski, Tadeusz Warchol
  • 7-Substituted tetracycline compounds
    Publication number: 20040224928
    Abstract: The present invention pertains, at least in part, to novel 7-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: May 24, 2004
    Publication date: November 11, 2004
    Applicants: Trustees of Tufts College, Paratek Pharmaceuticals, Inc.
    Inventors: Mark L. Nelson, Roger Frechette, Peter Viski, Mohamed Ismail, Todd Bowser, Beena Bhatia, David Messersmith, Laura McIntyre, Darrell Koza, Glen Rennie, Paul Sheahan, Paul Hawkins, Atul Verma, Tadeusz Warchol, Upul Bandarage
  • Inhibitors of TACE
    Publication number: 20040186088
    Abstract: The present invention relates to compounds that inhibit TACE, compositions thereof, and methods of using those compounds and compositions for treating diseases.
    Type: Application
    Filed: December 19, 2003
    Publication date: September 23, 2004
    Inventors: Upul Bandarage, Jon H. Come, Emanuele Perola, Govinda Rao Bhisetti, Jeffrey O. Saundres
  • 7-substituted tetracycline compounds
    Publication number: 20030055025
    Abstract: The present invention pertains, at least in part, to novel 7-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: June 29, 2001
    Publication date: March 20, 2003
    Inventors: Mark L. Nelson, Roger Frechette, Peter Viski, Mohamed Ismail, Todd Bowser, Beena Bhatia, David Messersmith, Laura McIntyre, Darrell Koza, Glen Rennie, Paul Sheahan, Paul Hawkins, Atul Verma, Tadeusz Warchol, Upul Bandarage