Patents by Inventor Urban Liebel

Urban Liebel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10698192
    Abstract: A microscopy system provides for scanning a sample by a microscope, which is at least in part electrically or electronically controllable and in which a plurality of images or digital images are generatable in a scanning operation at different times and/or different locations of the sample. The microscopy system includes a control computer configured to control the microscope, as well as further computers that are integratable into the microscopy system such that an adaptation of the microscopy system is possible dynamically and/or during the scanning operation using at least one of the further computers.
    Type: Grant
    Filed: March 14, 2019
    Date of Patent: June 30, 2020
    Assignees: LEICA MICROSYSTEMS CMS GMBH, EMBL EUROPEAN MOLECULAR BIOLOGY LABORATORY
    Inventors: Frank Sieckmann, Urban Liebel
  • Patent number: 10642018
    Abstract: An imaging device for a microscope (20) is disclosed that comprises a plurality of individual light sources (40) and a detector (15). The plurality of the individual light sources (40) is mounted on a translation stage (110). The imaging device further includes moveable optics arranged to direct a light path (45) onto a stationary sample (60) and collect reflected or fluoresced radiation from the sample (60).
    Type: Grant
    Filed: September 6, 2016
    Date of Patent: May 5, 2020
    Assignees: KARLSRUHER INSTITUT FÜR TECHNOLOGIE, DITABIS DIGITAL BIOMEDICAL IMAGING SYSTEMS AG, EUROPEAN MOLECULAR BIOLOGY LABORATORY
    Inventors: Lars Hufnagel, Uros Krzic, Urban Liebel
  • Patent number: 10481374
    Abstract: A method for scanning a sample using an electrically or electronically controllable microscope includes performing a continuous scanning of the sample so as to repeatedly generate a plurality of images of the sample, each of the plurality of images corresponding to a different time, the microscope being controlled via a control computer during the scanning. The plurality of images are analyzed using at least one second computer connected via a network, wherein the at least one second computer is configured to classify each of the plurality of images as one of interesting and non-interesting while the continuous scanning of the sample with the microscope continues. The continuous scanning of the sample is automatically influenced based on the classifying of the images performed by the at least one second computer.
    Type: Grant
    Filed: February 7, 2017
    Date of Patent: November 19, 2019
    Assignees: LEICA MICROSYSTEMS CMS GMBH, EMBL EUROPEAN MOLECULAR BIOLOGY LABORATORY
    Inventors: Frank Sieckmann, Urban Liebel
  • Publication number: 20190212538
    Abstract: A microscopy system provides for scanning a sample by a microscope, which is at least in part electrically or electronically controllable and in which a plurality of images or digital images are generatable in a scanning operation at different times and/or different locations of the sample. The microscopy system includes a control computer configured to control the microscope, as well as further computers that are integratable into the microscopy system such that an adaptation of the microscopy system is possible dynamically and/or during the scanning operation using at least one of the further computers.
    Type: Application
    Filed: March 14, 2019
    Publication date: July 11, 2019
    Inventors: Frank Sieckmann, Urban Liebel
  • Patent number: 9824259
    Abstract: The present invention relates to a device and a method for microscopy (100) of a plurality of samples (102), wherein the device comprises:—a first optical detector (106, 108), which is designed to consecutively adopt a plurality of measuring positions and to detect first image data (200) of a sample (104) with a first spatial resolution at each measuring position;—an image data analyser device which is designed to determine for each sample (202) a region (204) of the sample to be examined represented within the first image data (200) in each case;—a second optical detector (110, 112), which is coupled to the first optical detector (106, 108) in such a manner that the second optical detector (110, 112) tracks the first optical detector (106, 108) and therefore the second optical detector (110, 112) adopts measuring positions which the first optical detector (106, 108) had previously adopted.
    Type: Grant
    Filed: October 29, 2013
    Date of Patent: November 21, 2017
    Assignee: KARLSRUHER INSTITUT FUER TECHNOLOGIE
    Inventors: Urban Liebel, Jochen Gehrig
  • Publication number: 20170146782
    Abstract: A method for scanning a sample using an electrically or electronically controllable microscope includes performing a continuous scanning of the sample so as to repeatedly generate a plurality of images of the sample, each of the plurality of images corresponding to a different time, the microscope being controlled via a control computer during the scanning. The plurality of images are analyzed using at least one second computer connected via a network, wherein the at least one second computer is configured to classify each of the plurality of images as one of interesting and non-interesting while the continuous scanning of the sample with the microscope continues. The continuous scanning of the sample is automatically influenced based on the classifying of the images performed by the at least one second computer.
    Type: Application
    Filed: February 7, 2017
    Publication date: May 25, 2017
    Inventors: Frank Sieckmann, Urban Liebel
  • Patent number: 9588329
    Abstract: A method for scanning a sample using an electrically or electronically controllable microscope, includes scanning the sample so as to generate a plurality of images of the sample, each of the plurality of images corresponding to at least one of a different region of the sample and a different time. The microscope is controlled via a control computer during the scanning. The plurality of images are analyzed using at least one second computer connected via a network. The plurality of images are classified and/or the scanning is influenced based on the analyzing.
    Type: Grant
    Filed: September 6, 2007
    Date of Patent: March 7, 2017
    Assignees: LEICA MICROSYSTEMS CMS GMBH, EMBL EUROPEAN MOLECULAR BIOLOGY LABORATORY
    Inventors: Frank Sieckmann, Urban Liebel
  • Publication number: 20160377852
    Abstract: An imaging device for a microscope (20) is disclosed that comprises a plurality of individual light sources (40) and a detector (15). The plurality of the individual light sources (40) is mounted on a translation stage (110). The imaging device further includes moveable optics arranged to direct a light path (45) onto a stationary sample (60) and collect reflected or fluoresced radiation from the sample (60).
    Type: Application
    Filed: September 6, 2016
    Publication date: December 29, 2016
    Inventors: Lars Hufnagel, Uros Krzic, Urban Liebel
  • Publication number: 20150317507
    Abstract: The present invention relates to a device and a method for microscopy (100) of a plurality of samples (102), wherein the device comprises:—a first optical detector (106, 108), which is designed to consecutively adopt a plurality of measuring positions and to detect first image data (200) of a sample (104) with a first spatial resolution at each measuring position;—an image data analyser device which is designed to determine for each sample (202) a region (204) of the sample to be examined represented within the first image data (200) in each case;—a second optical detector (110, 112), which is coupled to the first optical detector (106, 108) in such a manner that the second optical detector (110, 112) tracks the first optical detector (106, 108) and therefore the second optical detector (110, 112) adopts measuring positions which the first optical detector (106, 108) had previously adopted.
    Type: Application
    Filed: October 29, 2013
    Publication date: November 5, 2015
    Applicants: Acquifer AG, Karlsruher Institut für Technologie
    Inventors: Urban Liebel, Jochen Gehrig
  • Publication number: 20120302467
    Abstract: The present invention relates to a method for making arrays or patterns comprising hydrophilic areas and hydrophobic background surrounding the hydrophilic areas, methods of cultivating cells using these arrays or patterns, and uses of these arrays or patterns in cell cultivation methods, e.g. for cell patterning, cell screenings, cell transfection and cell co-culturing.
    Type: Application
    Filed: November 29, 2011
    Publication date: November 29, 2012
    Applicant: Karlsruher Institut fur Technologie
    Inventors: Pavel Levkin, Florian Geyer, Urban Liebel
  • Patent number: 8199407
    Abstract: An immersion objective for microscopic investigation of a specimen is provided wherein an outer lens is disposed in an objective body. A delivery device including a cap that is disposed over the objective body so as to form a space adapted to receive an immersion liquid is also provided. The cap is open in a region of the outer lens so as to form a gap with the outer lens. The cap includes at least one connector configured to provide a continuous supply of the immersion liquid to the space so that the immersion liquid emerges through the gap to a region between the outer lens and at least one of the specimen and a specimen slide.
    Type: Grant
    Filed: September 7, 2007
    Date of Patent: June 12, 2012
    Assignees: Leica Microsystems CMS GmbH, EMBL European Molecular Biology Laboratory
    Inventors: Urban Liebel, Siegfried Winkler, Frank Sieckmann
  • Publication number: 20100103253
    Abstract: A method for scanning a sample using an electrically or electronically controllable microscope, includes scanning the sample so as to generate a plurality of images of the sample, each of the plurality of images corresponding to at least one of a different region of the sample and a different time. The microscope is controlled via a control computer during the scanning. The plurality of images are analyzed using at least one second computer connected via a network. The plurality of images are classified and/or the scanning is influenced based on the analyzing.
    Type: Application
    Filed: September 6, 2007
    Publication date: April 29, 2010
    Applicants: LEICA MICROSYSTEMS CMS GMBH, EMBL EUROPEAN MOLECULAR BIOLOGY LABORATORY
    Inventors: Frank Sieckmann, Urban Liebel
  • Publication number: 20100027109
    Abstract: An immersion objective for microscopic investigation of a specimen is provided wherein an outer lens is disposed in an objective body. A delivery device including a cap that is disposed over the objective body so as to form a space adapted to receive an immersion liquid is also provided. The cap is open in a region of the outer lens so as to form a gap with the outer lens. The cap includes at least one connector configured to provide a continuous supply of the immersion liquid to the space so that the immersion liquid emerges through the gap to a region between the outer lens and at least one of the specimen and a specimen slide.
    Type: Application
    Filed: September 7, 2007
    Publication date: February 4, 2010
    Applicants: Leica Microsystems CMS GmbH, EMBL European Molecular Biology Laboratory
    Inventors: Urban Liebel, Siegfried Winkler, Frank Sieckmann
  • Publication number: 20060216211
    Abstract: A sample holder for handling samples to be viewed under a microscope, and which comprises a base frame 1 provided with a lower surface 2, an upper surface 3, and at least one receiving area 4 for at least one sample. In order to facilitate examination of a large number of samples, the sample holder is provided with a coupling area 5 on its upper surface for receiving at least one other functional element, such as a sample fixing element, a heating or cooling plate, or a cover.
    Type: Application
    Filed: April 3, 2006
    Publication date: September 28, 2006
    Inventors: Urban Liebel, Rainer Pepperkok, Siegfried Winkler, Helmut Schaar, Wolfgang Dilling