Patents by Inventor Urban Liebel
Urban Liebel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10698192Abstract: A microscopy system provides for scanning a sample by a microscope, which is at least in part electrically or electronically controllable and in which a plurality of images or digital images are generatable in a scanning operation at different times and/or different locations of the sample. The microscopy system includes a control computer configured to control the microscope, as well as further computers that are integratable into the microscopy system such that an adaptation of the microscopy system is possible dynamically and/or during the scanning operation using at least one of the further computers.Type: GrantFiled: March 14, 2019Date of Patent: June 30, 2020Assignees: LEICA MICROSYSTEMS CMS GMBH, EMBL EUROPEAN MOLECULAR BIOLOGY LABORATORYInventors: Frank Sieckmann, Urban Liebel
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Patent number: 10642018Abstract: An imaging device for a microscope (20) is disclosed that comprises a plurality of individual light sources (40) and a detector (15). The plurality of the individual light sources (40) is mounted on a translation stage (110). The imaging device further includes moveable optics arranged to direct a light path (45) onto a stationary sample (60) and collect reflected or fluoresced radiation from the sample (60).Type: GrantFiled: September 6, 2016Date of Patent: May 5, 2020Assignees: KARLSRUHER INSTITUT FÜR TECHNOLOGIE, DITABIS DIGITAL BIOMEDICAL IMAGING SYSTEMS AG, EUROPEAN MOLECULAR BIOLOGY LABORATORYInventors: Lars Hufnagel, Uros Krzic, Urban Liebel
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Patent number: 10481374Abstract: A method for scanning a sample using an electrically or electronically controllable microscope includes performing a continuous scanning of the sample so as to repeatedly generate a plurality of images of the sample, each of the plurality of images corresponding to a different time, the microscope being controlled via a control computer during the scanning. The plurality of images are analyzed using at least one second computer connected via a network, wherein the at least one second computer is configured to classify each of the plurality of images as one of interesting and non-interesting while the continuous scanning of the sample with the microscope continues. The continuous scanning of the sample is automatically influenced based on the classifying of the images performed by the at least one second computer.Type: GrantFiled: February 7, 2017Date of Patent: November 19, 2019Assignees: LEICA MICROSYSTEMS CMS GMBH, EMBL EUROPEAN MOLECULAR BIOLOGY LABORATORYInventors: Frank Sieckmann, Urban Liebel
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Publication number: 20190212538Abstract: A microscopy system provides for scanning a sample by a microscope, which is at least in part electrically or electronically controllable and in which a plurality of images or digital images are generatable in a scanning operation at different times and/or different locations of the sample. The microscopy system includes a control computer configured to control the microscope, as well as further computers that are integratable into the microscopy system such that an adaptation of the microscopy system is possible dynamically and/or during the scanning operation using at least one of the further computers.Type: ApplicationFiled: March 14, 2019Publication date: July 11, 2019Inventors: Frank Sieckmann, Urban Liebel
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Patent number: 9824259Abstract: The present invention relates to a device and a method for microscopy (100) of a plurality of samples (102), wherein the device comprises:—a first optical detector (106, 108), which is designed to consecutively adopt a plurality of measuring positions and to detect first image data (200) of a sample (104) with a first spatial resolution at each measuring position;—an image data analyser device which is designed to determine for each sample (202) a region (204) of the sample to be examined represented within the first image data (200) in each case;—a second optical detector (110, 112), which is coupled to the first optical detector (106, 108) in such a manner that the second optical detector (110, 112) tracks the first optical detector (106, 108) and therefore the second optical detector (110, 112) adopts measuring positions which the first optical detector (106, 108) had previously adopted.Type: GrantFiled: October 29, 2013Date of Patent: November 21, 2017Assignee: KARLSRUHER INSTITUT FUER TECHNOLOGIEInventors: Urban Liebel, Jochen Gehrig
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Publication number: 20170146782Abstract: A method for scanning a sample using an electrically or electronically controllable microscope includes performing a continuous scanning of the sample so as to repeatedly generate a plurality of images of the sample, each of the plurality of images corresponding to a different time, the microscope being controlled via a control computer during the scanning. The plurality of images are analyzed using at least one second computer connected via a network, wherein the at least one second computer is configured to classify each of the plurality of images as one of interesting and non-interesting while the continuous scanning of the sample with the microscope continues. The continuous scanning of the sample is automatically influenced based on the classifying of the images performed by the at least one second computer.Type: ApplicationFiled: February 7, 2017Publication date: May 25, 2017Inventors: Frank Sieckmann, Urban Liebel
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Patent number: 9588329Abstract: A method for scanning a sample using an electrically or electronically controllable microscope, includes scanning the sample so as to generate a plurality of images of the sample, each of the plurality of images corresponding to at least one of a different region of the sample and a different time. The microscope is controlled via a control computer during the scanning. The plurality of images are analyzed using at least one second computer connected via a network. The plurality of images are classified and/or the scanning is influenced based on the analyzing.Type: GrantFiled: September 6, 2007Date of Patent: March 7, 2017Assignees: LEICA MICROSYSTEMS CMS GMBH, EMBL EUROPEAN MOLECULAR BIOLOGY LABORATORYInventors: Frank Sieckmann, Urban Liebel
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Publication number: 20160377852Abstract: An imaging device for a microscope (20) is disclosed that comprises a plurality of individual light sources (40) and a detector (15). The plurality of the individual light sources (40) is mounted on a translation stage (110). The imaging device further includes moveable optics arranged to direct a light path (45) onto a stationary sample (60) and collect reflected or fluoresced radiation from the sample (60).Type: ApplicationFiled: September 6, 2016Publication date: December 29, 2016Inventors: Lars Hufnagel, Uros Krzic, Urban Liebel
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Publication number: 20150317507Abstract: The present invention relates to a device and a method for microscopy (100) of a plurality of samples (102), wherein the device comprises:—a first optical detector (106, 108), which is designed to consecutively adopt a plurality of measuring positions and to detect first image data (200) of a sample (104) with a first spatial resolution at each measuring position;—an image data analyser device which is designed to determine for each sample (202) a region (204) of the sample to be examined represented within the first image data (200) in each case;—a second optical detector (110, 112), which is coupled to the first optical detector (106, 108) in such a manner that the second optical detector (110, 112) tracks the first optical detector (106, 108) and therefore the second optical detector (110, 112) adopts measuring positions which the first optical detector (106, 108) had previously adopted.Type: ApplicationFiled: October 29, 2013Publication date: November 5, 2015Applicants: Acquifer AG, Karlsruher Institut für TechnologieInventors: Urban Liebel, Jochen Gehrig
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Publication number: 20120302467Abstract: The present invention relates to a method for making arrays or patterns comprising hydrophilic areas and hydrophobic background surrounding the hydrophilic areas, methods of cultivating cells using these arrays or patterns, and uses of these arrays or patterns in cell cultivation methods, e.g. for cell patterning, cell screenings, cell transfection and cell co-culturing.Type: ApplicationFiled: November 29, 2011Publication date: November 29, 2012Applicant: Karlsruher Institut fur TechnologieInventors: Pavel Levkin, Florian Geyer, Urban Liebel
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Patent number: 8199407Abstract: An immersion objective for microscopic investigation of a specimen is provided wherein an outer lens is disposed in an objective body. A delivery device including a cap that is disposed over the objective body so as to form a space adapted to receive an immersion liquid is also provided. The cap is open in a region of the outer lens so as to form a gap with the outer lens. The cap includes at least one connector configured to provide a continuous supply of the immersion liquid to the space so that the immersion liquid emerges through the gap to a region between the outer lens and at least one of the specimen and a specimen slide.Type: GrantFiled: September 7, 2007Date of Patent: June 12, 2012Assignees: Leica Microsystems CMS GmbH, EMBL European Molecular Biology LaboratoryInventors: Urban Liebel, Siegfried Winkler, Frank Sieckmann
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Publication number: 20100103253Abstract: A method for scanning a sample using an electrically or electronically controllable microscope, includes scanning the sample so as to generate a plurality of images of the sample, each of the plurality of images corresponding to at least one of a different region of the sample and a different time. The microscope is controlled via a control computer during the scanning. The plurality of images are analyzed using at least one second computer connected via a network. The plurality of images are classified and/or the scanning is influenced based on the analyzing.Type: ApplicationFiled: September 6, 2007Publication date: April 29, 2010Applicants: LEICA MICROSYSTEMS CMS GMBH, EMBL EUROPEAN MOLECULAR BIOLOGY LABORATORYInventors: Frank Sieckmann, Urban Liebel
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Publication number: 20100027109Abstract: An immersion objective for microscopic investigation of a specimen is provided wherein an outer lens is disposed in an objective body. A delivery device including a cap that is disposed over the objective body so as to form a space adapted to receive an immersion liquid is also provided. The cap is open in a region of the outer lens so as to form a gap with the outer lens. The cap includes at least one connector configured to provide a continuous supply of the immersion liquid to the space so that the immersion liquid emerges through the gap to a region between the outer lens and at least one of the specimen and a specimen slide.Type: ApplicationFiled: September 7, 2007Publication date: February 4, 2010Applicants: Leica Microsystems CMS GmbH, EMBL European Molecular Biology LaboratoryInventors: Urban Liebel, Siegfried Winkler, Frank Sieckmann
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Publication number: 20060216211Abstract: A sample holder for handling samples to be viewed under a microscope, and which comprises a base frame 1 provided with a lower surface 2, an upper surface 3, and at least one receiving area 4 for at least one sample. In order to facilitate examination of a large number of samples, the sample holder is provided with a coupling area 5 on its upper surface for receiving at least one other functional element, such as a sample fixing element, a heating or cooling plate, or a cover.Type: ApplicationFiled: April 3, 2006Publication date: September 28, 2006Inventors: Urban Liebel, Rainer Pepperkok, Siegfried Winkler, Helmut Schaar, Wolfgang Dilling