Patents by Inventor Uri Alon

Uri Alon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100298166
    Abstract: Nucleic acid construct systems are disclosed. The constructs comprise: (i) a first nucleic acid construct comprising a first nucleic acid sequence encoding a first reporter polypeptide linked to an additional nucleic acid sequence capable of inserting the first nucleic acid construct into a genome of a host cell such that an endogenous polypeptide covalently attached to the first reporter polypeptide is expressed in the cell; and (ii) a second nucleic acid construct comprising a second nucleic acid sequence encoding a second reporter polypeptide, linked to an additional nucleic acid sequence capable of inserting in a non-directed manner the second nucleic acid construct into a genome of a host cell such that an endogenous polypeptide covalently attached to the second reporter polypeptide is expressed in the cell, wherein the first reporter polypeptide and the second reporter polypeptide are distinguishable.
    Type: Application
    Filed: January 22, 2009
    Publication date: November 25, 2010
    Inventors: Uri Alon, Alex Sigal, Ron Milo, Tamar Danon, Ariel Cohen, Naama Geva-Zatorsky, Milana Frenkel-Morgenstern, Lydia Cohen, Natalie Perzov, Eran Eden
  • Publication number: 20090271123
    Abstract: A method for analyzing the temporal behavior of gene expression for a group of genes which are part of a biological system or subsystem. Preferably, such an analysis enables the order of expression of such genes to be determined. More preferably, the temporal behavior of gene expression is assessed according to the analysis of the kinetics of gene transcription. According to a preferred embodiment of the present invention, the kinetics of gene transcription are measured according to promoter activity of a plurality of genes. More preferably, such kinetics are measured in a living organism or a portion of such an organism, such as a cell for example. For single-celled organisms, such as bacteria for example, the kinetics may easily be measured for the entirety of the living organism.
    Type: Application
    Filed: April 30, 2009
    Publication date: October 29, 2009
    Inventor: Uri ALON
  • Publication number: 20050208493
    Abstract: A method for analyzing the temporal behavior of gene expression for a group of genes which are part of a biological system or subsystem. Preferably, such an analysis enables the order of expression of such genes to be determined. More preferably, the temporal behavior of gene expression is assessed according to the analysis of the kinetics of gene transcription. According to a preferred embodiment of the present invention, the kinetics of gene transcription are measured according to promoter activity of a plurality of genes. More preferably, such kinetics are measured in a living organism or a portion of such an organism, such as a cell for example. For single-celled organisms, such as bacteria for example, the kinetics may easily be measured for the entirety of the living organism.
    Type: Application
    Filed: June 5, 2003
    Publication date: September 22, 2005
    Applicant: Yeda Research And Development Co., Ltd.
    Inventor: Uri Alon
  • Patent number: 6834646
    Abstract: A positive-pressure respirator hood assembly comprising, a gas-impermeable hood made of a flexible material, formed with at least a transparent visor portion; a gas treatment unit, comprising a filter and a power-operated blower to force air through the filter and generate a positive pressure within the hood; a one-way purge valve for facilitating the exhaust of exhaled gases and moisture from the hood; and a sealing portion for sealingly securing the hood over a body portion of the user; the respirator hood assembly is designed to be compactly received in a container and to be deployed into an operative state automatically, whereby a user is provided protection from toxic gases and particulate material.
    Type: Grant
    Filed: December 19, 2001
    Date of Patent: December 28, 2004
    Assignee: Testa Technologies T.T. Ltd.
    Inventors: Uri Alon, Yaron Reshef, Elhanan Schaham
  • Publication number: 20040204925
    Abstract: A method for analyzing data, such as biological data for example, for identifying one or more network motifs, or recurring patterns of relationships and/or behavioral connections between the components of a complex system. The method of the present invention is optionally and preferably applied to biological systems, such as gene regulatory systems for example.
    Type: Application
    Filed: December 29, 2003
    Publication date: October 14, 2004
    Inventors: Uri Alon, Shalev Itzkovitz, Reuven Levitt, Nadav Kashtan, Ron Milo
  • Publication number: 20030228579
    Abstract: A method for analyzing the temporal behavior of gene expression for a group of genes which are part of a biological system or subsystem. Preferably, such an analysis enables the order of expression of such genes to be determined. More preferably, the temporal behavior of gene expression is assessed according to the analysis of the kinetics of gene transcription. According to a preferred embodiment of the present invention, the kinetics of gene transcription are measured according to promoter activity of a plurality of genes. More preferably, such kinetics are measured in a living organism or a portion of such an organism, such as a cell for example. For single-celled organisms, such as bacteria for example, the kinetics may easily be measured for the entirety of the living organism.
    Type: Application
    Filed: June 5, 2002
    Publication date: December 11, 2003
    Inventor: Uri Alon
  • Publication number: 20030111074
    Abstract: A positive-pressure respirator hood assembly comprising, a gas-impermeable hood made of a flexible material, formed with at least a transparent visor portion; a gas treatment unit, comprising a filter and a power-operated blower to force air through the filter and generate a positive pressure within the hood; a one-way purge valve for facilitating the exhaust of exhaled gases and moisture from the hood; and a sealing portion for sealingly securing the hood over a body portion of the user; the respirator hood assembly is designed to be compactly received in a container and to be deployed into an operative state automatically, whereby a user is provided protection from toxic gases and particulate material.
    Type: Application
    Filed: December 19, 2001
    Publication date: June 19, 2003
    Applicant: TESTA TECHNOLOGIES T.T. LTD.
    Inventors: Uri Alon, Yaron Reshef, Elhanan Schaham
  • Publication number: 20030044836
    Abstract: Systems and methods for enhanced quantitative analysis of hybridization intensity measurements obtained from oligonucleotide probes and other probes exposed to target samples are provided by virtue of the present invention. One embodiment ameliorates the effects of high frequency noise superimposed on a hybridization intensity measurement signal measured over successive probe alignments to a target sample sequence. Detection of expressed genes and ESTs and quantitative measurement of expression level may be improved. Mutation detection and base calling may be improved.
    Type: Application
    Filed: September 30, 2002
    Publication date: March 6, 2003
    Applicant: Princeton University, Office of Technology & Trademark Licensing
    Inventors: Arnold J. Levine, Uri Alon
  • Patent number: 6489096
    Abstract: Systems and methods for enhanced quantitative analysis of hybridization intensity measurements obtained from oligonucleotide probes and other probes exposed to target samples are provided by virtue of the present invention. One embodiment ameliorates the effects of high frequency noise superimposed on a hybridization intensity measurement signal measured over successive probe alignments to a target sample sequence. Detection of expressed genes and ESTs and quantitative measurement of expression level may be improved. Mutation detection and base calling may be improved.
    Type: Grant
    Filed: October 15, 1998
    Date of Patent: December 3, 2002
    Assignee: Princeton University
    Inventors: Arnold J. Levine, Uri Alon
  • Publication number: 20020099832
    Abstract: The present invention concerns a method for accessing a computerized network suck as the Internet, wherein the user can choose whether to browse the Internet under his actual user name or under a user alias.
    Type: Application
    Filed: January 22, 2001
    Publication date: July 25, 2002
    Inventors: Tal Yaegerman, Yehoshua Horesh, Uri Alon, Yaron Reshef
  • Patent number: 5839221
    Abstract: An insecticidal device is provided which has a panel of a color having insect attracting properties, preferably yellow, and a spherical body of another color, preferably red. The spherical body is capable of defusing a liquid which contains an insect attractant and is combined with the panel in a manner that they form together an essentially flat panel having hemispherical bulges formed by the spherical body. A specific panel, which can be used as a panel in the above device and can be used as an independent insecticidal device is also provided.
    Type: Grant
    Filed: June 21, 1995
    Date of Patent: November 24, 1998
    Assignee: Ronpal Ltd.
    Inventors: Eyal Ron, Neriel Paglin, Yaron Reshef, Uri Alon
  • Patent number: 5094520
    Abstract: An axiosymmetric eccentric spherical polycarbonate lens (2) for goggles (1), comprising inner (7) and outer (8) spherical surfaces defined by centers of curvature 0.sub.1 and 0.sub.2 and by radii R.sub.1 and R.sub.2, respectively, 0.sub.1 and 0.sub.2 being both located on the lens's axis of symmetry (5), at a distance D from each other, the lens being more distal from 0.sub.1 than from 0.sub.2, the length of R.sub.2 being about 1.025-1.035 R.sub.1, and that of D about 0.0510-0.0564.
    Type: Grant
    Filed: February 22, 1991
    Date of Patent: March 10, 1992
    Assignee: Bezalel Research and Development Ltd.
    Inventors: Yaron Reshef, Uri Alon