Patents by Inventor Urs A. Ramel
Urs A. Ramel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240226877Abstract: The present disclosure relates to enhancements in diagnostic assays for detection of analytes. The improved assays are suitable for management of infections and pandemics in humans and animal reservoirs, including but not limited to SARS-CoV-2 (CoV2), and for measurement of biomarkers of disease (both human and veterinary).Type: ApplicationFiled: October 25, 2023Publication date: July 11, 2024Applicant: Trellis Bioscience, Inc.Inventors: Urs A. Ramel, Joel Blatt, Lawrence M. Kauvar, Stote Ellsworth, Ralph A. Tripp, Leslie P. Jones
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Publication number: 20240131508Abstract: The present disclosure relates to enhancements in diagnostic assays for detection of analytes. The improved assays are suitable for management of infections and pandemics in humans and animal reservoirs, including but not limited to SARS-CoV-2 (CoV2), and for measurement of biomarkers of disease (both human and veterinary).Type: ApplicationFiled: October 24, 2023Publication date: April 25, 2024Applicant: Trellis Bioscience, Inc.Inventors: Urs A. Ramel, Joel Blatt, Lawrence M. Kauvar, Stote Ellsworth, Ralph A. Tripp, Leslie P. Jones
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Patent number: 10386278Abstract: A system for mixing a sample with a combined buffer includes a sampler body, the sampler body including a first reservoir and a second reservoir. The system further includes a first separator forming a first enclosure with the sampler body for the first reservoir. The system further includes a second separator forming a second enclosure with the sampler body for the first reservoir. The system further includes a third separator, in conjunction with the second separator, forming a third enclosure and a fourth enclosure, respectively, both in conjunction with the sampler body, for the second reservoir.Type: GrantFiled: May 16, 2017Date of Patent: August 20, 2019Assignee: Polymer Technology Systems, Inc.Inventors: Jeffrey A. Pierce, Bao Phan, Urs A. Ramel
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Publication number: 20170336305Abstract: A system for mixing a sample with a combined buffer includes a sampler body, the sampler body including a first reservoir and a second reservoir. The system further includes a first separator forming a first enclosure with the sampler body for the first reservoir. The system further includes a second separator forming a second enclosure with the sampler body for the first reservoir. The system further includes a third separator, in conjunction with the second separator, forming a third enclosure and a fourth enclosure, respectively, both in conjunction with the sampler body, for the second reservoir.Type: ApplicationFiled: May 16, 2017Publication date: November 23, 2017Inventors: Jeffrey A. Pierce, Bao Phan, Urs A. Ramel
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Patent number: 8574919Abstract: A structure for controlling fluid flow from a sample receiving pad into a lateral flow assay test strip, including: a lateral flow assay test strip; a sample pad abutting the lateral flow assay test strip; a pinch wall positioned to direct fluid flow from the sample pad to the lateral flow assay test strip; a top support structure positioned on top of the test strip; and a bottom support structure positioned underneath the test strip, wherein each of the top and bottom support structures comprise a plurality of separate spaced-apart support ribs positioned along the length of the test strip.Type: GrantFiled: March 8, 2010Date of Patent: November 5, 2013Assignee: Bayer HealthCare LLCInventors: Urs A. Ramel, Dillan Tay
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Publication number: 20100226822Abstract: A structure for controlling fluid flow from a sample receiving pad into a lateral flow assay test strip, including: a lateral flow assay test strip; a sample pad abutting the lateral flow assay test strip; a pinch wall positioned to direct fluid flow from the sample pad to the lateral flow assay test strip; a top support structure positioned on top of the test strip; and a bottom support structure positioned underneath the test strip, wherein each of the top and bottom support structures comprise a plurality of separate spaced-apart support ribs positioned along the length of the test strip.Type: ApplicationFiled: March 8, 2010Publication date: September 9, 2010Applicant: Bayer HealthCare LLCInventors: Urs A. Ramel, Dillan Tay
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Patent number: 7771655Abstract: A device for preparing a fluid sample for use in a fluid analyte meter, including: a first portion, comprising: a septum piercing projection, a capillary channel, and a vent on an outer surface of the first portion; and a second portion, comprising: a treatment solution chamber, and a septum sealing the treatment solution chamber, wherein the vent is open when the first portion of the device is initially inserted into the second portion of the device, and wherein the vent is closed when the first portion of the device is fully inserted into the second portion of the device.Type: GrantFiled: July 12, 2006Date of Patent: August 10, 2010Assignee: Bayer HealthCare LLCInventor: Urs A. Ramel
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Patent number: 7749770Abstract: A method of preparing a fluid sample for use in a fluid analyte monitor, the method including drawing a fluid sample into a capillary channel in a body having a septum piercing projection; piercing a first septum covering a treatment solution chamber with the septum piercing projection, thereby exposing the fluid sample in the capillary channel to the contents of the treatment solution chamber; mixing the fluid sample with the contents of the treatment solution chamber; and piercing a second septum covering the treatment solution channel such that the mixed fluid and treatment solution chamber contents are received into a fluid analyte meter. The method may also include shaking the treatment solution chamber with the capillary channel therein, thereby mixing the fluid sample with the contents of the treatment solution chamber.Type: GrantFiled: August 10, 2009Date of Patent: July 6, 2010Assignee: Bayer HealthCare LLCInventors: Hoa Nguyen, Urs A. Ramel, Jeffrey A. Pierce
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Patent number: 7674615Abstract: A structure for controlling fluid flow from a sample receiving pad into a lateral flow assay test strip, including: a lateral flow assay test strip; a sample pad abutting the lateral flow assay test strip; a pinch wall positioned to direct fluid flow from the sample pad to the lateral flow assay test strip; a top support structure positioned on top of the test strip; and a bottom support structure positioned underneath the test strip, wherein each of the top and bottom support structures comprise a plurality of separate spaced-apart support ribs positioned along the length of the test strip.Type: GrantFiled: May 4, 2005Date of Patent: March 9, 2010Assignee: Bayer HealthCare LLCInventors: Urs A. Ramel, Dillan Tay
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Publication number: 20100041164Abstract: A method of preparing a fluid sample for use in a fluid analyte monitor, the method including drawing a fluid sample into a capillary channel in a body having a septum piercing projection; piercing a first septum covering a treatment solution chamber with the septum piercing projection, thereby exposing the fluid sample in the capillary channel to the contents of the treatment solution chamber; mixing the fluid sample with the contents of the treatment solution chamber; and piercing a second septum covering the treatment solution channel such that the mixed fluid and treatment solution chamber contents are received into a fluid analyte meter. The method may also include shaking the treatment solution chamber with the capillary channel therein, thereby mixing the fluid sample with the contents of the treatment solution chamber.Type: ApplicationFiled: August 10, 2009Publication date: February 18, 2010Applicant: Bayer HealthCare LLCInventors: Hoa Nguyen, Urs A. Ramel, Jeffrey A. Pierce
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Patent number: 7588724Abstract: A device for preparing a fluid sample for use in a fluid analyte meter, including: (a) a first portion, comprising: a capillary channel dimensioned to receive a fluid sample therein, an internal nozzle in communication with the capillary channel, a mixing chamber in communication with both the capillary channel and the internal nozzle, and a dispensing nozzle in communication with the mixing chamber; (b) a treatment solution chamber covered by a septum; and (c) a second portion that is moveable with respect to the first portion to pierce the septum such that contents of the treatment solution chamber mix with contents of the capillary channel in the mixing chamber and are ejected through the dispensing nozzle when the second portion is moved with respect to the first portion.Type: GrantFiled: January 25, 2005Date of Patent: September 15, 2009Assignee: Bayer HealthCare LLCInventors: Hoa Nguyen, Urs A. Ramel, Jeffrey A. Pierce
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Publication number: 20080081378Abstract: A device for preparing a fluid sample for use in a fluid analyte meter, including: a first portion, comprising: a septum piercing projection, a capillary channel, and a vent on an outer surface of the first portion; and a second portion, comprising: a treatment solution chamber, and a septum sealing the treatment solution chamber, wherein the vent is open when the first portion of the device is initially inserted into the second portion of the device, and wherein the vent is closed when the first portion of the device is fully inserted into the second portion of the device.Type: ApplicationFiled: July 12, 2006Publication date: April 3, 2008Applicant: METRIKA, INC.Inventor: Urs A. Ramel
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Patent number: 5540709Abstract: A lancet device includes a body within which is slidably located a trigger and fixedly located a base. The base contains, in an armed position, the lance with its needle and a spring affixed to the lance. The trigger includes a mechanism to release the lance during use.In a preferred embodiment, the lancet device of the present invention is self-activated by the finger (or other body part) to be pierced. Depression of the trigger with the finger releases the lance and the spring so that the needle protrudes through an orifice in the end of the trigger and pierces the tissue. Because the spring is held in a pre-armed position, release of the spring is consistent, and reproducibility of incision is well controlled.Type: GrantFiled: November 16, 1994Date of Patent: July 30, 1996Assignee: Actimed Laboratories, Inc.Inventor: Urs A. Ramel
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Patent number: 5366470Abstract: A lancet device includes a body within which is slidably located a trigger and fixedly located a base. The base contains, in an armed position, the lance with its needle and a spring affixed to the lance. The trigger includes a mechanism to release the lance during use.In a preferred embodiment, the lancet device of the present invention is self-activated by the finger (or other body part) to be pierced. Depression of the trigger with the finger releases the lance and the spring so that the needle protrudes through an orifice in the end of the trigger and pierces the tissue. Because the spring is held in a pre-armed position, release of the spring is consistent, and reproducibility of incision is well controlled.Type: GrantFiled: September 13, 1993Date of Patent: November 22, 1994Inventor: Urs A. Ramel
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Patent number: 5260221Abstract: A self-contained assay device is provided, where an analyte may be detected or be quantitated by measuring the distance of a detectable signal from a predetermined site. The device employs two strips separated by a gap, where a flow path is completed by movement of a sample receiving pad into the gap. The movement of the sample receiving pad also results in release of a reagent solution which is then transported through the pad into the quantitation area where the amount of analyte may be determined. Various chemistries may be employed for providing a detectable signal.Type: GrantFiled: July 2, 1991Date of Patent: November 9, 1993Inventors: Urs A. Ramel, Michael P. Allen, Prithipal Singh
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Patent number: 4987085Abstract: Constructions are provided for removing interfering red blood cells from a blood sample and providing a measured amount of serum or plasma to a pad. The pad serves as a bridge for the transfer of reagent between two bibulous strips, resulting in transfer of reagent solution through the pad and transport of a material to be measured to the measuring region of the strips. Particularly, glass fiber membranes are used in conjunction with cellulosic membranes to minimize red blood cell lysis, remove red blood cells and provide a measured amount of sample.Type: GrantFiled: March 16, 1989Date of Patent: January 22, 1991Assignee: Chemtrak Inc.Inventors: Michael P. Allen, Urs A. Ramel, Anthony J. DeLizza
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Patent number: 4959324Abstract: A self-contained assay device is provided, where an analyte may be detected or be quantitated by measuring the distance of a detectable signal from a predetermined site. The device employs two strips separated by a gap, where a flow path is completed by movement of a sample receiving pad into the gap. The movement of the sample receiving pad also results in release of a reagent solution which is then transported through the pad into the quantitation area where the amount of analyte may be determined. Various chemistries may be employed for providing a detectable signal.Type: GrantFiled: May 18, 1989Date of Patent: September 25, 1990Assignee: ChemTrak, Inc.Inventors: Urs A. Ramel, Michael P. Allen, Prithipal Singh
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Patent number: D540953Type: GrantFiled: May 2, 2006Date of Patent: April 17, 2007Assignee: Metrika, Inc.Inventors: Urs A. Ramel, Dillan Tay
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Patent number: D561905Type: GrantFiled: May 2, 2006Date of Patent: February 12, 2008Assignee: Metrika, Inc.Inventors: Urs A. Ramel, Dillan Tay