Patents by Inventor Ursula Müller
Ursula Müller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11780827Abstract: The invention relates to substituted 3-phenoxyazetidin-1-yl-pyrazines of general formula (I) which are agonists of GPR52, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to the 3-phenoxyazetidin-1-yl-pyrazines of general formula (I) for use as a medicament, pharmaceutical compositions comprising the 3-phenoxyazetidin-1-yl-pyrazines of general formula (I) and processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.Type: GrantFiled: March 29, 2021Date of Patent: October 10, 2023Assignees: Boehringer Ingelheim International GmbH, Arena Pharmaceuticals, Inc.Inventors: Kai Gerlach, Graeme Semple, Yifeng Xiong, Barbara Bertani, Marco Ferrara, Giacomo Fossati, Scott Hobson, Uta Friederike Lessel, Frank Runge, Ursula Mueller-Vieira, Julian Wippich
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Patent number: 11691960Abstract: The present invention relates to novel 2-[thiophen-2-yl)formamido]-N-(phenyl)-2-methylpropanamides of formula A and pharmaceutically acceptable salts thereof, wherein R1 to R3 are as defined herein. The invention also relates to processes for the preparation of these compound, pharmaceutical compositions containing them and their use in therapy, particularly in the treatment or prevention of conditions in which inhibition of the indoleamine 2,3-dioxygenase 1 (IDO1) enzyme may be beneficial.Type: GrantFiled: November 4, 2021Date of Patent: July 4, 2023Assignee: Boehringer Ingelheim International GmbHInventors: Stephan Georg Mueller, Kelly Allers, Klaus Klinder, Ursula Mueller-Vieira, Henning Priepke, Alexander Pautsch
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Publication number: 20230131465Abstract: The invention relates to 3-phenoxyazetidin-1-yl-heteroaryl pyrrolidine derivatives of general formula (I) which are agonists of GPR52, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to the 3-phenoxyazetidin-1-yl-heteroaryl pyrrolidine derivatives of general formula (I) for use as a medicament, pharmaceutical compositions comprising at least a compound of general formula (I) and processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.Type: ApplicationFiled: September 9, 2022Publication date: April 27, 2023Applicants: Boehringer Ingelheim International GmbH, Arena Pharmaceuticals, Inc.Inventors: Kai Gerlach, Daniela Gavina Berta, Marco Ferrara, Kirsten Gutsche, Ursula Mueller-Vieira, Scott Hobson, Frank Runge, Graeme Semple, Viktor Vintonyak, Yifeng Xiong
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Publication number: 20220356172Abstract: The invention relates to substituted 3-phenoxyazetidin-1-yl-pyrazines of general formula (I) which are agonists of GPR52, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to the 3-phenoxyazetidin-1-yl-pyrazines of general formula (I) for use as a medicament, pharmaceutical compositions comprising the 3-phenoxyazetidin-1-yl-pyrazines of general formula (I) and processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.Type: ApplicationFiled: March 29, 2021Publication date: November 10, 2022Applicants: Boehringer Ingelheim International GmbH, Arena Pharmaceuticals, Inc.Inventors: Kai Gerlach, Graeme Semple, Yifeng Xiong, Barbara Bertani, Marco Ferrara, Giacomo Fossati, Scott Hobson, Uta Friederike Lessel, Frank Runge, Ursula Mueller-Vieira, Julian Wippich
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Publication number: 20220144796Abstract: The present invention relates to novel 2-[thiophen-2-yl)formamido]-N-(phenyl)-2-methylpropanamides of formula A and pharmaceutically acceptable salts thereof, wherein R1 to R3 are as defined herein. The invention also relates to processes for the preparation of these compound, pharmaceutical compositions containing them and their use in therapy, particularly in the treatment or prevention of conditions in which inhibition of the indoleamine 2,3-dioxygenase 1 (IDO1) enzyme may be beneficial.Type: ApplicationFiled: November 4, 2021Publication date: May 12, 2022Inventors: Stephan Georg MUELLER, Kelly ALLERS, Klaus KLINDER, Ursula MUELLER-VIEIRA, Henning PRIEPKE, Alexander PAUTSCH
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Patent number: 9271963Abstract: The invention relates to compounds for selectively inhibiting human corticosteroid synthases CYP1 1 B1 and CYP1 1 B2, and to the production and use thereof for treating hypercortisolism, diabetes mellitus, hyperaldosteronism, cardiac insufficiency, myocardial fibrosis, depression, age-related cognitive decline and metabolic syndrome.Type: GrantFiled: March 2, 2006Date of Patent: March 1, 2016Assignee: UNIVERSITAT DES SAARLANDESInventors: Rolf Hartmann, Marieke Voets, Ursula Müller-Vieira
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Patent number: 8523221Abstract: The invention relates to an airbag module (18) with a tear strip (13) for specific opening of a seat cover (20) under which the airbag module (18) is to be mounted, wherein a plurality of tear strips (13) is provided. Furthermore, the invention relates to a seat with one such airbag module and also to a manufacturing apparatus and to an assembly method for one such airbag module.Type: GrantFiled: July 10, 2009Date of Patent: September 3, 2013Assignee: Faurecia Autositze GmbHInventor: Ursula Müller
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Patent number: 8426104Abstract: Negative-working imageable elements can be imaged and processed to provide lithographic printing plates. These imageable elements are sensitive to infrared radiation but are insensitive to “white” light and thus can be more easily handled under white light conditions. These properties are possible by incorporating a filter dye having a ?max of from about 300 to about 500 nm into the imageable layer of the imageable elements.Type: GrantFiled: October 8, 2009Date of Patent: April 23, 2013Assignee: Eastman Kodak CompanyInventors: Christopher D. Simpson, Ursula Müller, Harald Baumann, Udo Dwars
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Publication number: 20120038131Abstract: The invention relates to an airbag module (18) with a tear strip (13) for specific opening of a seat cover (20) under which the airbag module (18) is to be mounted, wherein a plurality of tear strips (13) is provided. Furthermore, the invention relates to a seat with one such airbag module and also to a manufacturing apparatus and to an assembly method for one such airbag module.Type: ApplicationFiled: July 10, 2009Publication date: February 16, 2012Applicant: INOVA GmbHInventors: Helmut Müller, Ursula Müller
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Publication number: 20110086202Abstract: Negative-working imageable elements can be imaged and processed to provide lithographic printing plates. These imageable elements are sensitive to infrared radiation but are insensitive to “white” light and thus can be more easily handled under white light conditions. These properties are possible by incorporating a filter dye having a ?max of from about 300 to about 500 nm into the imageable layer of the imageable elements.Type: ApplicationFiled: October 8, 2009Publication date: April 14, 2011Inventors: Christopher D. Simpson, Ursula Müller, Harald Baumann, Udo Dwars
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Publication number: 20090221591Abstract: The invention relates to compounds for selectively inhibiting human corticosteroid synthases CYP1 1 B1 and CYP1 1 B2, and to the production and use thereof for treating hypercortisolism, diabetes mellitus, hyperaldosteronism, cardiac insufficiency, myocardial fibrosis, depression, age-related cognitive decline and metabolic syndrome.Type: ApplicationFiled: March 2, 2006Publication date: September 3, 2009Applicant: Universitat Des SaarlandesInventors: Rolf W. Hartmann, Marieke Voets, Ursula Müller-Vieira
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Patent number: 6884568Abstract: The use of certain mercapto compounds as shelf life improvers for infrared-sensitive lithographic printing plate precursors is disclosed. The compounds are five-membered heteroaromatic rings containing a nitrogen atom and at least one other heteroatom, which can be oxygen, sulfur, or another nitrogen atom, such that two ring heteroatoms are bonded to a ring carbon bearing a thiol group.Type: GrantFiled: April 25, 2002Date of Patent: April 26, 2005Assignee: Kodak Polychrome Graphics, LLCInventors: Hans-Joachim Timpe, Tobias Wittig, Ursula Müller
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Patent number: 6864040Abstract: The present invention relates to IR-sensitive compositions containing an initator system comprising: (a) at least one compound capable of absorbing IR radiation selected from triarylamine dyes, thiazolium dyes, indolium dyes, oxazolium dyes, cyanine dyes, polyaniline dyes, polypyrrole dyes, polythiophene dyes and phthalocyanine pigments (b) at least one compound capable of producing radicals selected from polyhaloalkyl-substituted compounds (c) at least one polycarboxylic acid represented by the following formula I wherein Y is selected from the group consisting of O, S and NR7, each of R4, R5 and R6 is independently selected from the group consisting of hydrogen, C1-C4 alkyl, aryl which is optionally substituted, —COOH and NR8CH2COOH, R7 is selected from the group consisting of hydrogen, C1-C6 alkyl, —CH2CH2OH, and C1-C5 alkyl substituted with -COOH, R8 is selected from the group consisting of —CH2COOH, —CH2OH and —(CH2)2N(CH2COOH)2 and r is 0, 1, 2 or 3 with the proviso that at least one of R4, R5, RType: GrantFiled: April 11, 2001Date of Patent: March 8, 2005Assignee: Kodak Polychrome Graphics LLCInventors: Ursula Müller, Tobias Wittig, Hans-Joachim Timpe
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Patent number: 6596460Abstract: A copolymer useful in radiation sensitive compositions for lithographic printing plates comprises the units A, B, C and D, wherein A is present in an amount of 0.5 to 30 wt.-% and is of the formula wherein R is hydrogen, C1-C4 alkyl, —CH═COOH or B is present in an amount of 5 to 35 wt.-% and is of the formula C is present in an amount of 10 to 55 wt.Type: GrantFiled: December 29, 2000Date of Patent: July 22, 2003Assignee: Kodak Polychrome Graphics LLCInventors: Hans-Joachim Timpe, Ursula Müller
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Patent number: 5955328Abstract: The present invention relates to a novel process for the preparation, by fermentation, of compounds of the formula I ##STR1## where R.sup.1 is hydrogen, fluorine, chlorine or bromine.Type: GrantFiled: January 16, 1996Date of Patent: September 21, 1999Assignee: BASF AktiengesellschaftInventors: Horst Ralf Staudenmaier, Bernhard Hauer, Wolfgang Ladner, Ursula Mueller, Uwe Pressler, Joachim Meyer
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Patent number: 5928912Abstract: A process for hydroxylating compounds of the formula ##STR1## where n, A and R.sup.1 to R.sup.4 have the meanings stated in the description, with the aid of microorganisms of the genus Beauveria.Type: GrantFiled: December 4, 1995Date of Patent: July 27, 1999Assignee: BASF AktiengesellschaftInventors: Wolfgang Ladner, Horst Ralf Staudenmaier, Bernhard Hauer, Ursula Mueller, Uwe Pressler, Joachim Meyer, Hardo Siegel
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Patent number: 5739017Abstract: 2-hydroxyphenylacetic acid is prepared from phenylacetic acid by fermentation with suitable microorganisms.Type: GrantFiled: June 21, 1996Date of Patent: April 14, 1998Assignee: BASF AktiengesellschaftInventors: Horst Ralf Staudenmaier, Bernhard Hauer, Wolfgang Ladner, Ursula Mueller, Uwe Pressler, Joachim Meyer
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Patent number: 5639643Abstract: The invention relates to a novel process for preparing 3-hydroxyphenylacetic acid by cultivating a fungus of the genus Rhizoctonia, Ceratobasidium and Pellicularia in the presence of a phenyl compound of the formula I ##STR1## where X is COOR, CH.sub.2 OH, CH.sub.2 NH.sub.2 or ##STR2## R is methyl, ethyl, hydrogen, sodium, potassium or ammonium.Type: GrantFiled: January 2, 1996Date of Patent: June 17, 1997Assignee: BASF AktiengesellschaftInventors: Horst Ralf Staudenmaier, Bernhard Hauer, Wolfgang Ladner, Ursula Mueller, Uwe Pressler, Joachim Meyer
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Patent number: 4837297Abstract: A process for the preparation of a prepolymer amide, by hydrolytically polymerizing a lactam/water mixture of a C.sub.12 -aminocarboxylic acid lactam at a temperature in the range from 240-360.degree. C. and a steam pressure in the range of 30-180 bar, and wherein the water content of the lactam/water mixture is in the range of 7.5-30% by weight.Type: GrantFiled: June 5, 1987Date of Patent: June 6, 1989Assignee: Huels AktiengesellschaftInventors: Klaus-Rudolf Meyer, Ingo Venn, Ursula Mueller-Niescher