Publication number: 20110257186
Abstract: Disclosed are methods of treating disorders of the eye by administering to a patient in need of such treatment a compound represented by the formula Wherein R1 and R2 are independently hydrogen, alkyl, substituted alkyl, cycloalkyl, alkynyl, substituted alkynyl, cyano, alkoxy, carboxamido, substituted carboxamido, and if R1 and R2 are alkyl, R1 and R2 may be joined with a bond or —(CH2)m— to produce a cycloalkyl, R3 and R4 are independently hydrogen, alkyl, hydroxyl, alkoxy, cyano, fluoro, and if R3 and R4 are alkyl, R3 and R4 may be joined with a bond or —(CH2)m— to produce a cycloalkyl, Q may be absent, hydrogen, alkyl, cycloalkyl, cycloalkenyl, alkoxy, substituted alkoxy, substituted thio, cyano, thionitrile, sulfonamide, substituted sulfonamide, substituted sulfonyl, aromatic, substituted aromatic, heteroaromatic, substituted heteroaromatic, or bicycloheteroaromatic, R5 is hydrogen, alkyl, cycloalkyl, or when R6 is also alkyl, together with R6 may form a heterocycloalkyl ring, R6 may be hydrogen, alky
Type:
Application
Filed:
April 12, 2011
Publication date:
October 20, 2011
Inventors:
Ursula V. Staubli, Yong-Xin Li, Alan C. Foster