Patents by Inventor Usha Ghatak

Usha Ghatak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tubulin binding ligands and corresponding prodrug constructs
    Patent number: 7091240
    Abstract: A diverse set of tubulin binding agents have been discovered which are structurally characterized, in a general sense, by a semi-rigid molecular framework capable of maintaining aryl-aryl, pseudo pi stacking distances appropriate for molecular recognition of tubulin. In phenolic or amino form, these ligands may be further functionalized to prepare phosphate esters, phosphate salts, phosphoramidates, and other prodrugs capable of demonstrating selective targeting and destruction of tumor cell vasculature.
    Type: Grant
    Filed: April 29, 2003
    Date of Patent: August 15, 2006
    Assignees: Oxigene, Inc., Baylor University
    Inventors: Kevin G. Pinney, Vani P. Mocharla, Zhi Chen, Charles M. Garner, Mallinath Hadimani, Raymond Kessler, James M. Dorsey, Klaus Edvardsen, David J. Chaplin, Joseph Prezioso, Usha Ghatak, legal representative, Anjan Ghatak, deceased
  • Tubulin binding agents and corresponding prodrug constructs
    Publication number: 20060142252
    Abstract: A diverse set of tubulin binding agents have been discovered which are structurally characterized, in a general sense, by a semi-rigid molecular framework capable of maintaining aryl-aryl, pseudo pi stacking distances appropriate for molecular recognition of tubulin. In phenolic or amino form, these ligands may be further functionalized to prepare phosphate esters, phosphate salts, phosphoramidates, and other prodrugs capable of demonstrating selective targeting and destruction of tumor cell vasculature.
    Type: Application
    Filed: February 21, 2006
    Publication date: June 29, 2006
    Inventors: Kevin Pinney, Vani Mocharla, Zhi Chen, Charles Garner, Anjan Ghatak, Usha Ghatak, Mallinath Hadimani, Jimmy Kessler, James Dorsey, Klaus Edvardson, David Chaplin, Joseph Prezioso
  • Tubulin binding ligands and corresponding prodrug constructs
    Publication number: 20040044059
    Abstract: A diverse set of tubulin binding agents have been discovered which are structurally characterized, in a general sense, by a semi-rigid molecular framework capable of maintaining aryl-aryl, pseudo pi stacking distances appropriate for molecular recognition of tubulin. In phenolic or amino form, these ligands may be further functionalized to prepare phosphate esters, phosphate salts, phosphoramidates, and other prodrugs capable of demonstrating selective targeting and destruction of tumor cell vasculature.
    Type: Application
    Filed: April 29, 2003
    Publication date: March 4, 2004
    Inventors: Kevin G. Pinney, Vani P. Mocharla, Zhi Chen, Charles M. Garner, Mallinath Hadimani, Raymond Kessler, James M. Dorsey, Klaus Edvardsen, David J. Chaplin, Joseph Prezioso, Anjan Ghatak, Usha Ghatak