Patents by Inventor Usha R. Ghatak, legal representative

Usha R. Ghatak, legal representative has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tubulin binding agents and corresponding prodrug constructs
    Patent number: 7001926
    Abstract: A diverse set of tubulin binding agents have been discovered which are structurally characterized, in a general sense, by a semi-rigid molecular framework capable of maintaining aryl-aryl, pseudo pi stacking distances appropriate for molecular recognition of tubulin. In phenolic or amino form, these ligands may be further functionalized to prepare phosphate esters, phosphate salts, phosphoramidates, and other prodrugs capable of demonstrating selective targeting and destruction of tumor cell vasculature.
    Type: Grant
    Filed: April 1, 2003
    Date of Patent: February 21, 2006
    Assignees: Oxigene, Inc., Baylor University
    Inventors: Kevin G. Pinney, Vani P. Mocharla, Zhi Chen, Usha R. Ghatak, legal representative, Mallinath Hadimani, Jimmy Kessler, James M. Dorsey, Klaus Edvardsen, David J. Chaplin, Joseph Prezioso, Anjan Ghatak, deceased