Abstract: A protective brush cover for sanitary use of brushes includes a shell having an open end. The shell is pliable. A plurality of penetrations is positioned through the shell. Each penetration is configured to allow passage of water through the shell and to reject passage of microbes through the shell. A closure is coupled to the shell adjacent to the open end. The shell is sized and configured such that the bristle section of a brush is insertable through the open end into the shell. The closure is positioned on the shell such that the closure is configured to reversibly couple to a handle of the brush to retain the shell in a covering position over the bristle section. The shell is configured to deter passage of microbes from the bristle section to a user.