Patents by Inventor Uwe B. Sleytr

Uwe B. Sleytr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7262281
    Abstract: On a carrier surface, a layer of S-layer proteins is produced as a carrier of functional molecules. A solution containing S-layer proteins in the form of monomers or oligomers is brought into contact with the carrier surface. Electrochemical conditions are produced in the solution such that the S-layer proteins (SU) have an electrical net charge by establishing an electrochemical potential difference between the solution and the carrier surface such that the S-layer proteins accumulate on the carrier surface. A two-dimensional crystalline structure is formed in the layer, and this can occur at a time separate from the deposition of the S-layer proteins, and under different electrochemical conditions.
    Type: Grant
    Filed: November 26, 2003
    Date of Patent: August 28, 2007
    Assignee: NANO-S Biotechnologie GmbH
    Inventors: Uwe B. Sleytr, Margit Sara, Wolfgang Kautek
  • Patent number: 7125707
    Abstract: A compound body can be constructed, using secondary cell wall polymers of prokaryotic microorganisms as bonding agent to anchor a monomolecular lattice to a support, with or without functional groups attached to the lattice. The lattice may be comprised of lipid or crystalline cell surface layer proteins. The support is illustrated by a micro-filtration membrane, a cell surface ultra-filtration membrane (SUM), and a micelle, respectively.
    Type: Grant
    Filed: April 24, 2001
    Date of Patent: October 24, 2006
    Assignee: Nano-S Biotechnologie GmbH
    Inventors: Uwe B. Sleytr, Margit Sara, Christoph Mader, Bernhard Schuster, Frank M. Unger
  • Publication number: 20040137527
    Abstract: On a carrier surface (CP), a layer of cell surface layer proteins (S-layer proteins) (SU, SM, SL) is produced as a carrier of functional molecules by virtue of a solution containing S-layer proteins in the form of monomers (SU) or oligomers (SM) being brought into contact with the carrier surface. To deposit the S-layer proteins, electrochemical conditions are set in the solution at which the S-layer proteins (SU) have an electrical net charge, and by setting the electrical potential of the carrier surface (CP) an electrochemical potential difference is produced between the solution and the carrier surface under whose effect the S-layer proteins from the solution accumulate on the carrier surface. In the layer formed in this way, a two-dimensional crystalline structure (SL) is then configured, wherein this can occur at a time separate from the deposition of the S-layer proteins and under different electrochemical conditions of the solution and/or the substrate.
    Type: Application
    Filed: November 26, 2003
    Publication date: July 15, 2004
    Applicant: NANO-S Biotechnologie GmbH
    Inventors: Uwe B. Sleytr, Margit Sara, Wolfgang Kautek
  • Publication number: 20040033576
    Abstract: Use of secondary cell wall polymer for the directed monomolecular bonding of molecules, preferably molecular layers and/or attachment of molecules to molecules of a support, as well as a compound body completed according to this application.
    Type: Application
    Filed: July 3, 2003
    Publication date: February 19, 2004
    Inventors: Uwe B Sleytr, Margit Sara, Chirstoph Mader, Bernhard Schuster, Frank M Unger
  • Patent number: 6296700
    Abstract: The invention relates to a method for producing a structured layer of defined functional molecules on the surface of a flat substrate, on the surface of which structures having different surface properties, at least as regards their hydrophobicity, are produced. A monolayer of a protein-containing crystalline cell surface layer (S layer) is deposited by recrystallization on said structured surface. Said S Layer binds only to those structured areas of the surface characterized by raised hydrophobicity. Alternatively, a structured S-layer may also be produced on the basis of a monolayer of an S layer deposited on a substrate by irradiating predefined sections of said layer to be structured with radiation of a predetermined intensity and energy. In the irradiated sections of the S-layer this suppresses the binding or intercalating ability of at least one surface.
    Type: Grant
    Filed: September 1, 1999
    Date of Patent: October 2, 2001
    Assignee: IMS-Ionen Mikrofabrikations Systems GmbH
    Inventors: Uwe B. Sleytr, Dietmar Pum, Hans Loschner
  • Patent number: 5043158
    Abstract: Superior pharmaceutical compositions which comprise carriers coupled to epitope-bearing moieties are described. The carriers are crystalline or paracrystalline glycoproteins, especially those derived from S-layers of microbial cell walls. These conjugates are capable of eliciting the formation of antibodies as well as a T-cell response.
    Type: Grant
    Filed: March 2, 1990
    Date of Patent: August 27, 1991
    Assignee: Chembiomed, Ltd.
    Inventors: Uwe B. Sleytr, Wolfgang Mundt, Paul Messner, Richard H. Smith, Frank M. Unger