Patents by Inventor Uwe Heinelt

Uwe Heinelt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted heterocyclo-norbornylamino derivatives, processes for their preparation, their use as medicaments or diagnostics, and medicaments comprising them
    Publication number: 20020173500
    Abstract: Substituted heterocyclo-norbornylaminoderivatives having: a) an exo-configuration nitrogen and an endo-fused five-membered ring or six-membered ring of the formula (I) or b) an exo-configuration nitrogen and an exo-fused five-membered ring or six-membered ring of the formula (Ia), 1
    Type: Application
    Filed: December 18, 2001
    Publication date: November 21, 2002
    Inventors: Uwe Heinelt, Hans-Jochen Lang, Klaus Wirth, Hans-Willi Jansen
  • Substituted benzimidazoles, processes for their preparation, their use as medicaments, and medicaments comprising them
    Publication number: 20020132842
    Abstract: The invention relates to the use of compounds of formula I for the production of a medicament for the treatment of illnesses which can be influenced by inhibition of the Na+/H+ exchanger, and to a medicament comprising them.
    Type: Application
    Filed: December 4, 2001
    Publication date: September 19, 2002
    Inventors: Armin Hofmeister, Uwe Heinelt, Hans-Jochen Lang, Markus Bleich, Klaus Wirth, Michael Gekle
  • Substituted cinnamic, acid guanidides, process for their preparation, their use as a medicament, and medicament comprising them
    Patent number: 6399824
    Abstract: Substituted cinnamic acid guanidides, process for their preparation, their use as a medicament or diagnostic, and medicament comprising them. Compounds of the formula I which may be obtained by reaction of a compound II with guanidine.
    Type: Grant
    Filed: September 18, 2001
    Date of Patent: June 4, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Armin Hofmeister, Max Hropot, Uwe Heinelt, Markus Bleich, Hans-Jochen Lang
  • Malonic acid derivatives, processes for their preparation, for their use and pharmaceutical compositions containing them
    Patent number: 6395737
    Abstract: New compounds for the inhibition of blood clotting proteins, and more particularly, to malonic acid derivatives of the formula I, wherein R(1), R(2), R(3), R(4), R(5), and R(6) have the meanings indicated in the claims. The compounds of formula I are inhibitors of the blood clotting enzyme factor Xa. Processes for the preparation of the compounds of formula I, methods of inhibiting factor Xa activity and of inhibiting blood clotting, use of the compounds of formula I in the treatment and prophylaxis of diseases, which can be treated or prevented by the inhibition of factor Xa activity such as thromboembolic diseases, and use of the compounds of formula I in the preparation of medicaments to be applied in such diseases. Compositions containing a compound of formula I in admixture or otherwise in association with an inert carrier, in particular pharmaceutical compositions containing a compound of formula I together with pharmaceutically acceptable carrier substances and auxiliary substances.
    Type: Grant
    Filed: December 28, 1999
    Date of Patent: May 28, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Elisabeth Defossa, Uwe Heinelt, Otmar Klingler, Gerhard Zoller, Hans Matter, Fahad A. Al-Obeidi, Armin Walser, Peter Wildgoose
  • SUBSTITUTED CINNAMIC, ACID GUANIDIDES, PROCESS FOR THEIR PREPARATION, THEIR USE AS A MEDICAMENT, AND MEDICAMENT COMPRISING THEM
    Publication number: 20020058710
    Abstract: Substituted cinnamic acid guanidides, process for their preparation, their use as a medicament or diagnostic, and medicament comprising them.
    Type: Application
    Filed: September 18, 2001
    Publication date: May 16, 2002
    Applicant: Aventis Pharma Deutschland GmbH.
    Inventors: Armin, Hofmeister, Max Hropot, Uwe Heinelt, Markus Bleich, Hans-Jochen Lang
  • Indole derivatives as inhibitors or factor Xa
    Patent number: 6337344
    Abstract: The present invention relates to the inhibition of blood clotting proteins, and more particularly, to indole derivatives of formula (I), in which R1a, R1b, R1c R1d, R2, R3, R4 and A are defined as indicated in the claims. The compounds of formula (I) are inhibitors of the blood clotting enzyme factor Xa. The invention also relates to processes for the preparation of the compounds of formula (I), to methods of inhibiting factor Xa activity and of inhibiting blood clotting, to use of the compounds of formula (I) in the treatment and prophylaxis of diseases which can be cured or prevented by the inhibition of factor Xa activity such as thromboembolic diseases, and to the use of the compounds of formula (I) in the preparation of medicaments to be applied in such diseases.
    Type: Grant
    Filed: August 14, 2000
    Date of Patent: January 8, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Elisabeth Defossa, Uwe Heinelt, Otmar Klingler, Gerhard Zoller, Fahad A. Al-Obeidi, Armin Walser, Peter Wildgoose, Hans Matter
  • Substituted norbornylamino derivatives, processes for their preparation, their use as medicaments or diagnostics, and a medicament comprising them
    Publication number: 20010023257
    Abstract: The application discloses substituted norbornylamino derivatives, processes for their preparation, their use as medicaments or diagnostics and a medicament comprising them
    Type: Application
    Filed: December 12, 2000
    Publication date: September 20, 2001
    Inventors: Uwe Heinelt, Hans-Jochen Lang, Heinz-Werner Kleemann, Jan-Robert Schwark, Klaus Wirth, Hans-Willi Jansen
  • Use of theophylline derivatives for the treatment and prophylaxis of states of shock, novel xanthine compounds and processes for their preparation
    Patent number: 6214992
    Abstract: Theophylline derivatives having at least one ether function in the structurally modified methyl radical in the 1-position that are useful in the treatment and prophylaxis of states of shock, new xanthine compounds having this substitution pattern, and processes for their preparation.
    Type: Grant
    Filed: June 4, 1997
    Date of Patent: April 10, 2001
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Ulrich Gebert, Erhard Wolf, Elisabeth Defossa, Uwe Heinelt, Hiristo Anagnostopulos, Karl Rudolphi, John J. Grome
  • Xanthine compounds having terminally animated alkynol side chains
    Patent number: 5965555
    Abstract: Compounds of the formula I, ##STR1## in which one of the radicals R.sup.1 and R.sup.3 is an alkynol residue of the formula Ia or Ib ##STR2## are suitable for producing pharmaceuticals having a neuroprotective effect.
    Type: Grant
    Filed: May 30, 1997
    Date of Patent: October 12, 1999
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Ulrich Gebert, Elisabeth Defossa, Uwe Heinelt, Karl Rudolphi, John J. Grome