Patents by Inventor Uwe Kruger

Uwe Kruger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4804681
    Abstract: Complexes of the general formula I[R.sup.1 (CH.sub.2).sub.m C(O)CR.sup.3 C(O)R.sup.2 ].sub.2+n MX.sub.2-n (I)wherein M denotes tin, titanium, zirconium or hafnium, R.sup.1 denotes hydrogen or a phenyl radical, it being possible for the phenyl radical to be monosubstituted or polysubstituted by fluorine, chlorine, bromine, nitro, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy or trifluoromethyl, R.sup.2 denotes methyl or R.sup.1, with the exception of hydrogen, R.sup.3 denotes hydrogen or chlorine, X denotes fluorine, chlorine or bromine, but not fluorine if M denotes zirconium or hafnium, m denotes the number 1 or 0, or, if R.sup.1 denotes hydrogen, the number 1 and n denotes the number 0, or, if M denotes zirconium or hafnium, the number 1 or 0, exhibit a cytostatic activity which is comparable to that of cisplatin and are less toxic than cisplatin. They are suitable for the produduction of medicaments having an anti-neoplastic action.
    Type: Grant
    Filed: May 21, 1982
    Date of Patent: February 14, 1989
    Inventors: Heimo Keller, Bernhard Keppler, Uwe Kruger, Rudolf Linder
  • Patent number: 4578401
    Abstract: Metal complexes of the general formula I[R.sup.1 (CH.sub.2).sub.m C(O)CR.sup.3 C(O)R.sup.2 ].sub.2 M(OR.sup.4).sub.2-n X.sub.n (I)wherein M denotes titanium, zirconium or hafnium, R.sup.1 denotes hydrogen, C.sub.1 -C.sub.8 -alkyl or phenyl, which can be monosubstituted or polysubstituted by fluorine, chlorine, bromine, nitro, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy or trifluoromethyl, R.sup.2 denotes C.sub.1 -C.sub.8 -alkyl, or phenyl, which can be monosubstituted or polysubstituted by fluorine, chlorine, bromine, nitro, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy or trifluoromethyl, R.sup.3 denotes hydrogen or phenyl, R.sup.4 denotes C.sub.1 -C.sub.18 -alkyl, which can be substituted by hydroxyl, C.sub.1 -C.sub.3 -alkylamino or alkali metal sulfonato groups, or denotes C.sub.5 -C.sub.8 -cycloalkyl, which can be substituted by C.sub.1 -C.sub.
    Type: Grant
    Filed: April 29, 1983
    Date of Patent: March 25, 1986
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Heimo Keller, Bernhard Keppler, Uwe Kruger, Rudolf Linder
  • Patent number: 4322439
    Abstract: The invention relates to .omega.-[2-(N-lower alkyl-benzamido)-phenyl]-alkanoic acids, their use and preparation, and medicaments containing them.
    Type: Grant
    Filed: September 21, 1979
    Date of Patent: March 30, 1982
    Assignee: BYK Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Kurt Klemm, Uwe Kruger, Erich Rapp, Horst Wolf, Ekkehard Kraas
  • Patent number: 3941453
    Abstract: Molecules with a group X which attracts electrons and comprises .pi.-electrons and conjugated therewith a group R which supplies electrons, of the formulaR -- Xin which X represents --COCF.sub.3, --COC.sub.6 H.sub.5 or --SO.sub.n CF.sub.3, n being 0 or 2, and R represents phenyl or (CH.sub.3).sub.2 N, as electrooptically active liquid inter alia have the advantage that they are achromatic compared with nitrobenzene.
    Type: Grant
    Filed: November 13, 1974
    Date of Patent: March 2, 1976
    Assignee: U.S. Philips Corporation
    Inventor: Uwe Kruger