Patents by Inventor Uwe Maskos

Uwe Maskos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190160052
    Abstract: The invention provides methods of reducing development of mild cognitive impairment and/or learning disorders and/or memory disorders in a subject suspected to have or suffering from Alzheimer's disease (AD). In some embodiments, the methods comprise administering a therapeutically effective amount of a beta-2 nicotinic acetylcholine receptor (n AChR) antagonist and/or beta-2 nAChRnegative allosteric modulator (NAM) to the subject over a therapeutic dosing period to thereby reduce the rate of development of mild cognitive impairment and/or learning disorders and/or memory disorders in the subject over the therapeutic dosing period.
    Type: Application
    Filed: May 15, 2017
    Publication date: May 30, 2019
    Inventors: Uwe MASKOS, Sylvia LOMBARDO, Julie CATTEAU, Morgane BESSON, Fani KOUKOULI
  • Patent number: 5436327
    Abstract: A method for synthesizing oligonucleotides by solid-phase methodology wherein the linkage between the oligonucleotide and the solid phase support is a non-labile phosphodiester. The spacer arm between the support and the phosphodiester is a hydrophilic group. The product of this method is an immobilized oligonucleotide which can be used in solid phase hybridization assays.
    Type: Grant
    Filed: March 20, 1991
    Date of Patent: July 25, 1995
    Assignee: Isis Innovation Limited
    Inventors: Edwin M. Southern, Uwe Maskos