Patents by Inventor Uwe Michelsen

Uwe Michelsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of ionic liquids for membrane protein extraction
    Patent number: 8143381
    Abstract: The present invention relates to the use of ionic liquids or of mixtures comprising at least one ionic liquid and at least one further solvent for the extraction of membrane proteins from biological samples, to methods for the extraction of membrane proteins, to a kit for the extraction of these proteins and to the use thereof.
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: March 27, 2012
    Assignee: Merck Patent GmbH
    Inventors: Joerg Von Hagen, Uwe Michelsen, Maria Wehsling
  • Method for the enrichment of phosphorylated and/or glycosylated analytes
    Publication number: 20110070663
    Abstract: The present invention relates to a method for the purification and isolation of phosphorylated and glycosylated analytes using titanium dioxide particles.
    Type: Application
    Filed: April 30, 2009
    Publication date: March 24, 2011
    Inventors: Joerg Von Hagen, Uwe Michelsen
  • METHOD FOR THE EXTRACTION OF MEMBRANE PROTEINS
    Publication number: 20100273993
    Abstract: The present invention relates to the use of linear, amphipathic carbohydrate polymers for the extraction of membrane proteins from biological samples, to a method for the extraction of membrane proteins, to a kit for the extraction of these proteins, and to the use thereof.
    Type: Application
    Filed: November 17, 2008
    Publication date: October 28, 2010
    Inventors: Joerg Von Hagen, Uwe Michelsen
  • USE OF IONIC LIQUIDS FOR MEMBRANE PROTEIN EXTRACTION
    Publication number: 20100029917
    Abstract: The present invention relates to the use of ionic liquids or of mixtures comprising at least one ionic liquid and at least one further solvent for the extraction of membrane proteins from biological samples, to methods for the extraction of membrane proteins, to a kit for the extraction of these proteins and to the use thereof.
    Type: Application
    Filed: October 18, 2007
    Publication date: February 4, 2010
    Applicant: MERCK PATENT GMBH
    Inventors: Joerg Von Hagen, Uwe Michelsen, Maria Wehsling
  • Use of ionic liquids for protein extraction
    Patent number: 7470778
    Abstract: The present invention relates to a method for the extraction of proteins, protein fragments and/or peptides from biological samples, where the extractants employed are ionic liquids of the general formula K+A?, to a kit for the extraction of proteins, protein fragments and/or peptides, and to the use thereof.
    Type: Grant
    Filed: June 12, 2006
    Date of Patent: December 30, 2008
    Assignee: Merck Patent GmbH
    Inventors: Jeorg von Hagen, Uwe Michelsen
  • Method and kit for the isolation of rna
    Publication number: 20070148651
    Abstract: The present invention relates to a method and a kit for the isolation of RNA in the presence of DNA. The isolation is carried out by binding to a magnetite solid phase, where the binding buffer produces a concentration of guanidinium thiocyanate of>2.5 mol/l, and a certain concentration of phosphate is present during the binding.
    Type: Application
    Filed: November 12, 2004
    Publication date: June 28, 2007
    Inventors: Uwe Michelsen, Karl Holschuh, Achim Schwammle
  • Use of ionic liquids for protein extraction
    Publication number: 20070026460
    Abstract: The present invention relates to a method for the extraction of proteins, protein fragments and/or peptides from biological samples, where the extractants employed are ionic liquids of the general formula K+A?, to a kit for the extraction of proteins, protein fragments and/or peptides, and to the use thereof.
    Type: Application
    Filed: June 12, 2006
    Publication date: February 1, 2007
    Inventors: Jeorg von Hagen, Uwe Michelsen
  • Method of isolating plasmid DNA
    Patent number: 6548253
    Abstract: The invention relates to a method of isolating plasmid DNA from microorganism cultures with the aid of solid-phase bodies. The solid-phase bodies can be silica gels, silicates, or glass-like materials and the solid-phase bodies can have magnetic properties. The solid-phase bodies are used for isolating the microorganisms and for isolating the plasmid DNA.
    Type: Grant
    Filed: June 8, 2001
    Date of Patent: April 15, 2003
    Assignee: Merck Patent GmbH
    Inventors: Karl Holschuh, Uwe Michelsen
  • Method for isolating and purifying nucleic acids
    Patent number: 6355792
    Abstract: The invention provides a method for isolating and purifying nucleic acids from liquid samples. The method comprises using a solid carrier which is essentially made of oxide inorganic materials containing hydroxyl groups (e.g., silica gel or hydroxylapatite). The nucleic acids are bound to the carrier material in the acidic pH range while they are eluted in the alkaline pH range.
    Type: Grant
    Filed: August 2, 2000
    Date of Patent: March 12, 2002
    Assignee: Merck Patent Gesellschaft
    Inventors: Uwe Michelsen, Karl Holschuh, Robertus Hendriks