Patents by Inventor Uwe Pohlen

Uwe Pohlen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6479033
    Abstract: The invention concerns a composition for the treatment of tumors, of (i) at least one cytostatic drug component which is unencapsulated or is encapsulated in a PEG-, immuno-, or immuno/PEG liposome, (ii) at least one of lyophilized starch particles, degradable starch particles, and gelatine, in combination with (iii) a contrasting agent containing at least one of iodine, gadolinium, and magnetite.
    Type: Grant
    Filed: June 16, 1997
    Date of Patent: November 12, 2002
    Assignee: Max Delbrück Zentrum für Molekulare Medizin
    Inventors: Regina Reszka, Uwe Pohlen, Detlef Stiller, Gerd Berger, Matthias Lippmann
  • Patent number: 6207133
    Abstract: The invention relates to a new anti-tumoral therapy agent based on liposome-encapsulated cytostatic agents and/or the metabolites thereof. The invention can be used in the pharmaceutical industry and in medicine. The aim of the invention is to build up drug targeting to combat cancer through suitable carrier systems. The invention is characterized by the fact that it clearly increases the concentration of cytostatic agents and residence time in tumors. At the same time, toxic side-effects on the remaining organs are reduced. The inventive agent contains PEG, immuno or immuno/PEG liposome-encapsulated cytostatic agents and/or the metabolites thereof, degradable starch particles and/or gelatin and/or nanoparticles, contrast agents containing iodine, gadolinium or magnetite. A preferred agent is characterized by the cytostatic agent Carboplatinum, encapsulated in SUV-PEG, starch particle Spherex or Gelfoam and the contrast agent Gadolinium-DTPA.
    Type: Grant
    Filed: June 6, 2000
    Date of Patent: March 27, 2001
    Assignee: Max-Delbrück-Centrum für Molekulare Medizin
    Inventors: Regina Reszka, Gerd Berger, Uwe Pohlen, Marion Jung