Patents by Inventor Uwe Sauer

Uwe Sauer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220259086
    Abstract: Method for making surface water drinkable, which method is aimed at reducing the suspended matter content, turbidity, organic matter content and colour of the water, and is characterised in that it comprises: ?a step of nanofiltering the water (2) through at least one nanofiltration membrane (2) which has a breakdown capacity between 800 Da and 2000 Da, preferably between 800 and 1000 Da, the nanofiltration step leading to the acquisition of a permeate (7) and a concentrate (5), ?wherein the nanofiltration step is carried out with a conversion rate greater than 95%, ?the method being carried out without any step of adding an anti-scaling agent or any step of remineralising the permeate.
    Type: Application
    Filed: June 11, 2020
    Publication date: August 18, 2022
    Inventors: Philippe Sauvignet, Henrik Gunnar Held, Uwe Sauer, Abdelkader Gaid
  • Patent number: 9914949
    Abstract: The present invention provides a method for enhancing N-acetylglucosamine production by usage of a recombinant Bacillus subtilis with a glcK knockout. This invention enhanced the production of GlcNAc by knocking out the glcK gene which encodes a glucokinase, thus eliminating the GlcNAc phosphorylation to GlcNAc-6-P. The specific growth rate and content of GlcNAc in the supernatant of the recombinant Bacillus subtilis with the glcK knockout were 0.15 h?1 and 3.0 g/L, respectively, which were 2.32 times and 2.14 times of those of the control strain without glcK knockout. The recombinant Bacillus subtilis of the present invention would be potentially useful for industrial production of GlcNAc.
    Type: Grant
    Filed: November 6, 2015
    Date of Patent: March 13, 2018
    Assignee: Jiangnan University
    Inventors: Long Liu, Jian Chen, Guocheng Du, Jianghua Li, Yanfeng Liu, Hannes Link, Uwe Sauer
  • Publication number: 20170009267
    Abstract: The present invention provides a method for enhancing N-acetylglucosamine production by usage of a recombinant Bacillus subtilis with a glcK knockout. This invention enhanced the production of GlcNAc by knocking out the glcK gene which encodes a glucokinase, thus eliminating the GlcNAc phosphorylation to GlcNAc-6-P. The specific growth rate and content of GlcNAc in the supernatant of the recombinant Bacillus subtilis with the glcK knockout were 0.15 h?1 and 3.0 g/L, respectively, which were 2.32 times and 2.14 times of those of the control strain without glcK knockout. The recombinant Bacillus subtilis of the present invention would be potentially useful for industrial production of GlcNAc.
    Type: Application
    Filed: November 6, 2015
    Publication date: January 12, 2017
    Applicant: Jiangnan University
    Inventors: Long Liu, Jian Chen, Guocheng Du, Jianghua Li, Yanfeng Liu, Hannes Link, Uwe Sauer
  • Patent number: 8722360
    Abstract: The present invention is directed to novel genes mediating the carbon catabolite repression (CCR) of gluconeogenic genes. Furthermore, the polypeptides encoded by said genes as well as the use of said genes in a process for the production of a target fermentation product is provided. Processes for generating such microorganisms are also provided by the present invention. The invention is also related to a genetically engineered microorganism and its use for the production of a target fermentation product, wherein the gluconeogenic genes are relieved from CCR within said microorganism.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: May 13, 2014
    Assignees: DSM IP Assets B.V., Institute National de la Recherche Agronomique
    Inventors: Stephane Aymerich, Hans-Peter Hohmann, Uwe Sauer
  • Publication number: 20090053778
    Abstract: The present invention relates to microorganisms and methods for producing at least one sulfur-containing compound.
    Type: Application
    Filed: July 20, 2005
    Publication date: February 26, 2009
    Applicant: FRANCE TELECOM
    Inventors: Uwe Sauer, Jorg Mampel, Oskar Zelder, Andrea Herold, Corinna Klopprogge, Hartwig Schroder, Stefan Haefner
  • Publication number: 20080311620
    Abstract: The present invention is directed to novel genes mediating the carbon catabolite repression (CCR) of gluconeogenic genes. Furthermore, the polypeptides encoded by said genes as well as the use of said genes in a process for the production of a target fermentation product is provided. Processes for generating such microorganisms are also provided by the present invention. The invention is also related to a genetically engineered microorganism and its use for the production of a target fermentation product, wherein the gluconeogenic genes are relieved from CCR within said microorganism.
    Type: Application
    Filed: December 22, 2005
    Publication date: December 18, 2008
    Applicants: DSM IP ASSETS B.V., INSTITUTE NATIONAL DE LA RECHERCHE AGRONOMIQUE
    Inventors: Stephane Aymerich, Hans-Peter Hohmann, Uwe Sauer
  • Patent number: 7344855
    Abstract: A process for the preparation of a target fermentation product comprising cultivation of an aerobic microorganism to produce such product, wherein in the microorganism the efficiency of the respiratory chain is increased, transformed and novel nucleotide sequences.
    Type: Grant
    Filed: February 20, 2003
    Date of Patent: March 18, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Hans-Peter Hohmann, Nigel John Mouncey, Uwe Sauer, Nicola Zamboni
  • Publication number: 20050153411
    Abstract: The present invention relates to a method for preparing an ethanol producing, xylose utilizing strain of Saccharomyces cerevisiae comprising genes for overexpression of xylose reductase, xylitol dehydrogenase and xylulokinase, wherein in addition to said genes for production o phosphoacetyltransferase, and acetaldehyde dehydrogenase are introduced and optionally overexpressed.
    Type: Application
    Filed: September 20, 2004
    Publication date: July 14, 2005
    Inventors: Fredrik Wahlbom, Marco Sonderegger, Uwe Sauer
  • Publication number: 20050124030
    Abstract: A process for the preparation of a target fermentation product comprising cultivation of an aerobic microorganism to produce such product, wherein in the microorganism the effi-ciency of the respiratory chain is increased, transformed microorganisms and novel nuc-leotide sequences.
    Type: Application
    Filed: February 20, 2003
    Publication date: June 9, 2005
    Inventors: Hans-Peter Hohmann, Nigel Mouncey, Uwe Sauer, Nicola Zamboni
  • Publication number: 20050014251
    Abstract: Plasmid vectors for expression in Caenorhabditis elegans harbouring a heat inducible promoter nucleotide sequence, a synthetic intron nucleotide sequence optionally containing a Shine-Dalgarno sequence for efficient shuttling between C. elegans and E. coli, optionally a nucleotide sequence coding for a nuclear localisation signal or secretion signal, a nucleotide sequence coding for a recognisable tag, optionally a nucleotide sequence coding for a fluorescent protein, a nucleotide sequence coding for a protease cleavage site, a multiple cloning site containing a nucleotide sequence coding for an eukaryotic, such as human, protein or a nucleic acid molecule and a nucleotide sequence coding for termination of translation, are described. Methods of particularly large scale production of eukaryotic, such as human, proteins and nucleic acid molecules in nematodes are also described. The methods comprise injection one or several different plasmid vectors into the gonad of C.
    Type: Application
    Filed: November 26, 2002
    Publication date: January 20, 2005
    Inventors: Uwe Sauer, Simon Tuck
  • Patent number: 6080315
    Abstract: In a process for the partial desalination of water, especially of drinking water, with a mixture of weakly acid cation exchangers and strongly basic anion exchangers, whereby the charged ion exchangers are regenerated by CO.sub.2 -containing water, if required, with the addition of CaCO.sub.3, CaCO.sub.3 /MgO, Ca(OH).sub.2 or the like. Simultaneous with the partial desalination, the organic carbon compounds present in the water are reduced, whereby the charged ion exchangers are intermittently regenerated with HCl, NaCl, NaOH, or a mixture of NaCl and NaOH.
    Type: Grant
    Filed: January 14, 1999
    Date of Patent: June 27, 2000
    Assignees: WABAG Wassertechnische Anlagen GmbH, Forschungszentrum Karlsruhe
    Inventors: Klaus Hagen, Uwe Sauer, Hans-Dieter Schmid, Peter Schultheiss, Werner Sauerschell, Wolfgang Holl, Astrid Stepanek
  • Patent number: 5931669
    Abstract: A dental apparatus is provided with a group of standard preparation instruments that are held in deposit devices having sensors allocated to each device to determine the configuration and deposit condition of the preparation instrument in the deposit device, the apparatus has a second group of non-preparation instruments which include image-acquiring instruments for diagnostic purposes. Both instrument groups or types share a personal computer with a keyboard and a monitor in common through one interface data where the instrument-related functions can be read in and read out so that the installed program of the personal computer is activated dependent on the particular instrument being used.
    Type: Grant
    Filed: March 22, 1995
    Date of Patent: August 3, 1999
    Assignee: Sirona Dental Systems GmbH & Co. KG
    Inventors: Peter Fornoff, Josef Pabst, Uwe Sauer, Ulrich Schulze-Ganzlin